Results 81 to 90 of about 5,089,703 (351)

Safety and Effectiveness of Struvite from Black Water and Urine as a Phosphorus Fertilizer [PDF]

, 2011
To ensure food supply, phosphorus must be recycled, for which an appealing method is using struvite fertilizer from human excreta. One struvite from black water and another from urine were assessed for safety under Dutch regulations, and for ...
Gell, K., Graaff, M., de, Kuntke, P., Ruijter, F.J., de, Smit, A.L.   +4 more
core   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Effect of surface dissolution by oxalic acid on flotation behavior of minerals

Journal of Materials Research and Technology, 2019
The surface dissolution pretreatment using oxalic acid as an organic agent was applied for modifying the surface properties of minerals and improving the selectivity of ilmenite flotation from its usual accompanied gangue minerals such as olivine ...
Omid Salmani Nuri, Mehdi Irannajad, Akbar Mehdilo   +2 more
doaj   +1 more source

A zero dimensional model of lithium-sulfur batteries during charge and discharge [PDF]

, 2015
Lithium-sulfur cells present an attractive alternative to Li-ion batteries due to their large energy density, safety, and possible low cost. Their successful commercialisation is dependent on improving their performance, but also on acquiring sufficient ...
Marinescu, M, Offer, G, Zhang, T
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Collagen-hyaluronic acid scaffolds for adipose tissue engineering. [PDF]

, 2010
Three-dimensional (3-D) in vitro models of the mammary gland require a scaffold matrix that supports the development of adipose stroma within a robust freely permeable matrix. 3-D porous collagen-hyaluronic acid (HA: 7.5% and 15%) scaffolds were produced
Cameron, RE, Campbell, JJ, Davidenko, N, Thian, ES, Watson, CJ   +4 more
core   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Solubility and Dissolution Rate Enhancement of Bilastine by Solid Dispersion Technique

Iraqi Journal of Pharmaceutical Sciences
Bilastine (BLS) is non-sedating new-brand H1 antihistamine that has selective peripheral effects, the drug has a problem of an insufficient aqueous solubility and accordingly low dissolution rate, and low bioavailability. Solid dispersion (SD) is one of
Mariam Hamid Ali, Kawther Khalid Ahmed
doaj   +1 more source

Equilibrium solubility versus intrinsic dissolution: characterization of lamivudine, stavudine and zidovudine for BCS classification

Brazilian Journal of Pharmaceutical Sciences, 2013
Solubility and dissolution rate of drugs are of major importance in pre-formulation studies of pharmaceutical dosage forms. The solubility improvement allows the drugs to be potential biowaiver candidates and may be a good way to develop more dose ...
André Bersani Dezani, Thaisa Marinho Pereira, Arthur Massabki Caffaro, Juliana Mazza Reis, Cristina Helena dos Reis Serra   +4 more
doaj   +1 more source

Effect of hydrophilic polymers on the solubility and dissolution enhancement of rivaroxaban/beta-cyclodextrin inclusion complexes

Heliyon, 2023
BCS class II drugs exhibit low aqueous solubility and high permeability. Such drugs often have an incomplete or erratic absorption profile. This study aimed to predict the effects of β-cyclodextrin (βCD) and different hydrophilic polymers (poloxamer 188 (
Waqas Haider Khan, Sajid Asghar, Ikram Ullah Khan, Muhammad Irfan, Abdulrahman Alshammari, Muhammad Shahid Riaz Rajoka, Rabia Munir, Pervaiz A. Shah, Ikrima Khalid, Fizza Abdul Razzaq, Syed Haroon Khalid   +10 more
doaj   +1 more source