Results 11 to 20 of about 480,652 (268)
Aggressive NK-cell leukemia: A rare entity with diagnostic and therapeutic challenge
Human Pathology: Case Reports, 2016 Aggressive natural killer cell leukemia (ANKL) is a rare neoplasm of mature natural killer cells, with an extremely poor overall survival, which is almost always EBV related, with majority of cases reported in East Asia.
Alia Nazarullah +4 more
doaj +1 more source
Hematology, Transfusion and Cell Therapy, 2023 Introduction: Myelodysplastic Neoplasm (MDS) is characterized by cytogenetic alterations in 40-60% of cases and 94% have at least one oncogenic mutation.
RTG Oliveira +9 more
doaj +1 more source
Aberrant DNA Methylation Is Associated with a Poor Outcome in Juvenile Myelomonocytic Leukemia. [PDF]
PLoS ONE, 2015 Juvenile myelomonocytic leukemia (JMML), an overlap of myelodysplastic / myeloproliferative neoplasm, is an intractable pediatric myeloid neoplasm. Epigenetic regulation of transcription, particularly by CpG methylation, plays an important role in tumor ...
Hirotoshi Sakaguchi +18 more
doaj +1 more source
Mediterranean Journal of Hematology and Infectious Diseases, 2017 Therapy-related leukemia or therapy-related myeloid neoplasm are widely-used terms to designate leukemia developing in persons who previously received anti-cancer therapy (for example, see references 1, 2), especially if the prior anti-cancer therapy ...
Robert Gale +2 more
doaj +1 more source
BMC Cancer, 2021 Background Mitochondrial fission regulator 2 (MTFR2) was involved in the progression and development of various cancers. However, the relationship between MTFR2 with lung adenocarcinoma (LUAD) had not been reported.
Cheng Chen +8 more
doaj +1 more source
DNA methylation and carcinogenesis in digestive neoplasms
World Journal of Gastroenterology, 1998 . Newly replicated DNA lacks thismethylation in the nascent strand. Shortly after thepassage of the replication fork, a maintenanceDNA-MTase methylates CpG dinucleotides on thenewly synthesized strand, thereby recreating thespectrum of methyl groups that existed prior toreplication.
Javed, Yakoob +3 more
openaire +2 more sources
DNA copy number amplification profiling of human neoplasms [PDF]
Oncogene, 2006 DNA copy number amplifications activate oncogenes and are hallmarks of nearly all advanced tumors. Amplified genes represent attractive targets for therapy, diagnostics and prognostics. To investigate DNA amplifications in different neoplasms, we performed a bibliomics survey using 838 published chromosomal comparative genomic hybridization studies and
S, Myllykangas +5 more
openaire +2 more sources
Synthesis and Antitumor Activity of a GSH Inert Bisphosphonate Platinum (II) Complex
Journal of Chemistry, 2022 Osteosarcoma is a highly aggressive neoplasm. Traditional platinum chemotherapeutic agents for osteosarcoma inevitably have acquired drug resistance and serious side effects, which have limited their utility.
Lu Ma +7 more
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2021 Here we show that surface-enhanced Raman scattering (SERS) analysis captures the relative hypomethylation of DNA from patients with acute leukemia associated with Down syndrome (AL-DS) compared with patients diagnosed with transient leukemia associated ...
Vlad Moisoiu +24 more
doaj +1 more source
Human Pathology Reports, 2022 It is generally accepted that choriocarcinoma is a trophoblastic tumor of gestational origin during the reproductive period, but this neoplasm can rarely occur after menopause or be non-gestational making diagnosis a real challenge.
Alina Magnaeva +4 more
doaj +1 more source