Results 11 to 20 of about 502,740 (312)

DNA Copy Number Losses in Human Neoplasms [PDF]

The American Journal of Pathology, 1999
This review summarizes reports of recurrent DNA sequence copy number losses in human neoplasms detected by comparative genomic hybridization. Recurrent losses that affect each of the chromosome arms in 73 tumor types are tabulated from 169 reports. The tables are available online at http://www.amjpathol.org and http://www.
S, Knuutila, Y, Aalto, K, Autio, A M, Björkqvist, W, El-Rifai, S, Hemmer, T, Huhta, E, Kettunen, S, Kiuru-Kuhlefelt, M L, Larramendy, T, Lushnikova, O, Monni, H, Pere, J, Tapper, M, Tarkkanen, A, Varis, V M, Wasenius, M, Wolf, Y, Zhu   +18 more
openaire   +2 more sources

DNA copy number amplification profiling of human neoplasms [PDF]

Oncogene, 2006
DNA copy number amplifications activate oncogenes and are hallmarks of nearly all advanced tumors. Amplified genes represent attractive targets for therapy, diagnostics and prognostics. To investigate DNA amplifications in different neoplasms, we performed a bibliomics survey using 838 published chromosomal comparative genomic hybridization studies and
S, Myllykangas, J, Himberg, T, Böhling, B, Nagy, J, Hollmén, S, Knuutila   +5 more
openaire   +2 more sources

Blastic plasmacytoid dendritic cell neoplasm: Genomics mark epigenetic dysregulation as a primary therapeutic target [PDF]

, 2019
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive hematologic malignancy for which there is still no effective B therapy.
Abate F., Agostinelli C., Amente S., Berti E., Bertolini F., Brundu F., Cerroni L., Dellino G. I., Etebari M., Facchetti F., Falini B., Fuligni F., Indio V., Laginestra M. A., Melle F., Motta G., Orecchioni S., Paulli M., Piccioni R., Pileri A., Pileri S. A., Pimpinelli N., Rabadan R., Rossi M., Sabattini E., Sapienza M. R., Tabanelli V., Talarico G., Tarantino G., Tripodo C., Truni M.   +30 more
core   +2 more sources

A metastatic secretory gastric plasmacytoma with aberrant CD3 expression in a dog [PDF]

, 2017
A 10-year-old crossbred dog was presented with a 6-week history of hematemesis, melena, anorexia, and lethargy. Clinical evaluation revealed a gastric mass with a regional lymphadenomegaly as well as a monoclonal gammopathy manifesting as ...
Atherton, Matthew J., Morris, Joanna S., Sharpe, Sam, Vazquez-Sanmartin, Samantha, Waugh, Elspeth M.   +4 more
core   +1 more source

Aberrant DNA Methylation Is Associated with a Poor Outcome in Juvenile Myelomonocytic Leukemia. [PDF]

PLoS ONE, 2015
Juvenile myelomonocytic leukemia (JMML), an overlap of myelodysplastic / myeloproliferative neoplasm, is an intractable pediatric myeloid neoplasm. Epigenetic regulation of transcription, particularly by CpG methylation, plays an important role in tumor ...
Hirotoshi Sakaguchi, Hideki Muramatsu, Yusuke Okuno, Hideki Makishima, Yinyan Xu, Yoko Furukawa-Hibi, Xinan Wang, Atsushi Narita, Kenichi Yoshida, Yuichi Shiraishi, Sayoko Doisaki, Nao Yoshida, Asahito Hama, Yoshiyuki Takahashi, Kiyofumi Yamada, Satoru Miyano, Seishi Ogawa, Jaroslaw P Maciejewski, Seiji Kojima   +18 more
doaj   +1 more source

Medical treatment of early stage and rare histological variants of epithelial ovarian cancer [PDF]

, 2015
Epithelial ovarian cancer is often considered a single pathological entity, but increasing evidence suggests that it is rather a group of different neoplasms, each with unique pathological characteristics, molecular features, and clinical behaviours ...
Biglia, Nicoletta, CODACCI PISANELLI, Giovanni, Colombo, Nicoletta, Cont, Nicoletta Tomasi, D'Alonzo, Marta, Ferrero, Annamaria, Peccatori, Fedro Alessandro   +6 more
core   +3 more sources

WHO HAS THERAPY-RELATED AML?

Mediterranean Journal of Hematology and Infectious Diseases, 2017
Therapy-related leukemia or therapy-related myeloid neoplasm are widely-used terms to designate leukemia developing in persons who previously received anti-cancer therapy (for example, see references 1, 2), especially if the prior anti-cancer therapy ...
Robert Gale, John M. Bennett, F. Owen Hoffman   +2 more
doaj   +1 more source

Evaluation of clinical value and potential mechanism of MTFR2 in lung adenocarcinoma via bioinformatics

BMC Cancer, 2021
Background Mitochondrial fission regulator 2 (MTFR2) was involved in the progression and development of various cancers. However, the relationship between MTFR2 with lung adenocarcinoma (LUAD) had not been reported.
Cheng Chen, Yang Tang, Wen-Dong Qu, Xu Han, Jie-Bin Zuo, Qing-Yong Cai, Gang Xu, Yong-Xiang Song, Xi-Xian Ke   +8 more
doaj   +1 more source

SINONASAL VERRUCOUS CARCINOMA Case series and review of literature [PDF]

, 2012
Verrucous carcinoma is a low grade malignancy and is a variant of squamous cell carcinoma. It is a rare tumour of the Sino nasal tract. The neoplasm occurs in older people usually in the seventh or eighth decade of life.
Iqbal, Irfan, K, SHEETAL, Mirza, Aneesa A, QAZI, SAJAD   +3 more
core   +3 more sources

DNA methylation and carcinogenesis in digestive neoplasms

World Journal of Gastroenterology, 1998
. Newly replicated DNA lacks thismethylation in the nascent strand. Shortly after thepassage of the replication fork, a maintenanceDNA-MTase methylates CpG dinucleotides on thenewly synthesized strand, thereby recreating thespectrum of methyl groups that existed prior toreplication.
Javed, Yakoob, Xue-Gong, Fan, Guo-Ling, Hu, Zheng, Zhang   +3 more
openaire   +2 more sources