Results 31 to 40 of about 2,091,584 (306)

Dependence of DNA-Histograms on The Sampling Techniques in Fine Needle Aspirates of the Breast

Analytical Cellular Pathology, 2002
48 fine needle aspiration biopsy (FNAB) samples from 25 breast cancer cases, originally used for cytodiagnosis were subjected to DNA cytometry. There were air dried smears stained with the MGG method, and samples stained with HE or PAP stain after 50 ...
A. Elzagheid, Y. Collan
doaj   +1 more source

miR-18a reactivates the Epstein-Barr virus through defective DNA damage response and promotes genomic instability in EBV-associated lymphomas

BMC Cancer, 2018
Background The Epstein-Barr virus (EBV) is closely associated with several types of malignancies. EBV is normally present in the latent state in the peripheral blood B cell compartment.
Pengfei Cao, Meili Zhang, Lujuan Wang, Buqing Sai, Jiuqi Tang, Zhaohui Luo, Cijun Shuai, Liyang Zhang, Zheng Li, Yanjin Wang, Guiyuan Li, Juanjuan Xiang   +11 more
doaj   +1 more source

DNA profile components predict malignant outcomes in select cases of intraductal papillary mucinous neoplasm with negative cytology

, 2018
Predicting malignancy in intraductal papillary mucinous neoplasm remains challenging. Integrated molecular pathology combines pancreatic fluid DNA and clinical factors into a malignant potential score. We sought to determine the utility of DNA components
Cockerill, Nathan J., Zyromski, Nicholas J., Simpson, Rachel E., Nakeeb, Attila, Yip-Schneider, Michele T., Schmidt, C. Max, Ceppa, Eugene P., Al-Haddad, Mohammad A., House, Michael G.   +8 more
core   +1 more source

Helicobacter pylori is undetectable in intraductal papillary mucinous neoplasm

, 2016
Background: About half of the world population is infected with Helicobacter pylori (H. pylori), a bacterium associated with gastric cancer and considered to be a risk factor for pancreatic ductal adenocarcinoma.
BAĞCI ÇULÇİ, PELİN, ÇELİKEL, ÇİĞDEM   +1 more
core   +1 more source

Molecular mechanisms and kinetics between DNA and DNA binding ligands [PDF]

, 2005
Sischka A, Tönsing K, Eckel R, et al. Molecular mechanisms and kinetics between DNA and DNA binding ligands. Biophysical Journal. 2005;88(1):404-411.Mechanical properties of single double-stranded DNA (dsDNA) in the presence of different binding ligands ...
Wilking, Sven David, Ros, Robert, Sischka, Andy, Eckel, Rainer, Tönsing, Katja, Sewald, Norbert ; https://orcid.org/, Anselmetti, Dario ; https://orcid.org/   +6 more
core   +1 more source

Copy number variations in urine cell-free DNA from bladder neoplasm patients

Molecular and Cellular Probes
Bladder cancer is a common malignancy, and its diagnosis is based on invasive procedures such as cystoscopy. Genetic aberrations play an important role in the development of many diseases, including bladder cancer.
Cuello Garcia Haider, Qichao Wang, Guangyue Wang, Yinfeng Wang, Yutong Fu, Zhoufan Zhang, Changling Cao, Fengcheng Xue, Haitao Liu, Qian Wang, Jie Zhou, Tingya Jiang, Jingyi Cao, Yang Zhou   +13 more
doaj   +1 more source

Co-occurrence and Mutual Exclusivity Analysis of DNA Methylation Reveals Distinct Subtypes in Multiple Cancers

Frontiers in Cell and Developmental Biology, 2020
Co-occurrence and mutual exclusivity (COME) of DNA methylation refer to two or more genes that tend to be positively or negatively correlated in DNA methylation among different samples.
Wubin Ding, Guoshuang Feng, Yige Hu, Geng Chen, Tieliu Shi, Tieliu Shi, Tieliu Shi   +6 more
doaj   +1 more source

DNA methylation-based classification of hematolymphoid neoplasms

Blood Advances
Abstract Accurate pathologic diagnosis of hematolymphoid neoplasms (HLN) is often challenging because of their complexity and heterogeneity. Genome-wide DNA methylation profiling has emerged as a valuable tool for tumor classification and diagnosis across malignancies, such as central nervous system neoplasms ...
Annapurna Saksena, Christin Siewert, Rust Turakulov, Omkar Singh, Zied Abdullaev, Ting Zhou, Jeremiah Karrs, Joao Victor Alves De Castro, Deanna Riley, Shannon Skarshaug, Valerie Zgonc, Lana Sultanaeva, Ruifeng Teng, Liqiang Xi, Robert J. Kreitman, Andreas von Deimling, Martí Duran-Ferrer, José Ignacio Martín-Subero, Elias Campo, Benjamin Englert, Julia Richter, Wolfram Klapper, Ioannis Anagnostopoulos, Andreas Rosenwald, Marion Wobser, Falko Fend, Leticia Quintanilla-Martinez, Gerardo Ferrer, Manel Esteller, Miguel A. Piris, Michael Hummel, Stefania Pittaluga, Mark Raffeld, Elaine S. Jaffe, David Capper, Kenneth Aldape   +35 more
openaire   +3 more sources

DNA Methylation-Based Classification of Kidney Neoplasms

Modern Pathology
Renal neoplasms are morphologically and molecularly heterogeneous, with their diagnosis often hindered by interobserver variability and overlapping microscopic features. A subset of cases is unclassifiable despite immunohistochemical, mutation, and cytogenetic-based diagnostic workup. Through examination of the genome-wide DNA methylation signatures of
Papanicolau-Sengos, Antonios, Singh, Omkar, Park, Kyung, Snuderl, Matija, Tretiakova, Maria, Merino, Maria, Stohr, Bradley, Simko, Jeff, Deng, Fang-Ming, Chan, Emily, Wu, Jasper, Barreto, Jairo, Gupta, Rohit, Park, Brian, Turakulov, Rust, Abdullaev, Zied, Solomon, David, Aldape, Kenneth   +17 more
openaire   +2 more sources

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source