Results 31 to 40 of about 479,747 (308)

Evaluation of clinical value and potential mechanism of MTFR2 in lung adenocarcinoma via bioinformatics

open access: yesBMC Cancer, 2021
Background Mitochondrial fission regulator 2 (MTFR2) was involved in the progression and development of various cancers. However, the relationship between MTFR2 with lung adenocarcinoma (LUAD) had not been reported.
Cheng Chen   +8 more
doaj   +1 more source

DNA methylation and carcinogenesis in digestive neoplasms

open access: yesWorld Journal of Gastroenterology, 1998
. Newly replicated DNA lacks thismethylation in the nascent strand. Shortly after thepassage of the replication fork, a maintenanceDNA-MTase methylates CpG dinucleotides on thenewly synthesized strand, thereby recreating thespectrum of methyl groups that existed prior toreplication.
Javed, Yakoob   +3 more
openaire   +2 more sources

Synthesis and Antitumor Activity of a GSH Inert Bisphosphonate Platinum (II) Complex

open access: yesJournal of Chemistry, 2022
Osteosarcoma is a highly aggressive neoplasm. Traditional platinum chemotherapeutic agents for osteosarcoma inevitably have acquired drug resistance and serious side effects, which have limited their utility.
Lu Ma   +7 more
doaj   +1 more source

SERS-Based Evaluation of the DNA Methylation Pattern Associated With Progression in Clonal Leukemogenesis of Down Syndrome

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Here we show that surface-enhanced Raman scattering (SERS) analysis captures the relative hypomethylation of DNA from patients with acute leukemia associated with Down syndrome (AL-DS) compared with patients diagnosed with transient leukemia associated ...
Vlad Moisoiu   +24 more
doaj   +1 more source

Primary Bartholin Adenocarcinoma: a Rare Case and Radiotherapy as Definitive Treatment [PDF]

open access: yesFolia Medica, 2021
Primary vulvar adenocarcinoma is a very rare neoplasm, accounting for only 1% of all gynecologic malignancies. Most of the glandular carcinomas originated from the Bartholin’s gland.
Lokot Donna Lubis   +2 more
doaj   +3 more sources

Non-gestational choriocarcinoma of ovary: Clinico-morphological features and diagnostic value of DNA polymorphism study

open access: yesHuman Pathology Reports, 2022
It is generally accepted that choriocarcinoma is a trophoblastic tumor of gestational origin during the reproductive period, but this neoplasm can rarely occur after menopause or be non-gestational making diagnosis a real challenge.
Alina Magnaeva   +4 more
doaj   +1 more source

Classification of Colon Cancer Patients Based on the Methylation Patterns of Promoters [PDF]

open access: yesGenomics & Informatics, 2016
Diverse somatic mutations have been reported to serve as cancer drivers. Recently, it has also been reported that epigenetic regulation is closely related to cancer development. However, the effect of epigenetic changes on cancer is still elusive.
Wonyoung Choi   +5 more
doaj   +1 more source

DNA FISH Diagnostic Assay on Cytological Samples of Thyroid Follicular Neoplasms [PDF]

open access: yesCancers, 2020
Although fine-needle aspiration cytology (FNAC) is helpful in determining whether thyroid nodules are benign or malignant, this distinction remains a cytological challenge in follicular neoplasms. Identification of genomic alterations in cytological specimens with direct and routine techniques would therefore have great clinical value.
Philippe Vielh   +18 more
openaire   +2 more sources

miR-18a reactivates the Epstein-Barr virus through defective DNA damage response and promotes genomic instability in EBV-associated lymphomas

open access: yesBMC Cancer, 2018
Background The Epstein-Barr virus (EBV) is closely associated with several types of malignancies. EBV is normally present in the latent state in the peripheral blood B cell compartment.
Pengfei Cao   +11 more
doaj   +1 more source

DNA profile components predict malignant outcomes in select cases of intraductal papillary mucinous neoplasm with negative cytology

open access: yes, 2018
Predicting malignancy in intraductal papillary mucinous neoplasm remains challenging. Integrated molecular pathology combines pancreatic fluid DNA and clinical factors into a malignant potential score. We sought to determine the utility of DNA components
Cockerill, Nathan J.   +8 more
core   +1 more source

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