Results 51 to 60 of about 502,740 (312)

RAB family gene expression in breast cancer cells under influence of paclitaxel [PDF]

, 2011
The aim of this study was to investigate the role of paclitaxel on RAB family of genes in primary breast cancer cell lines. The cancer breast cells obtained from 40 women during mastectomy were used to address this issue. The group included patients with
Andrzej Wilkolaski, Jolanta Rzymowska, Piotr Maj, Tadeusz Malewski   +3 more
core   +1 more source

Prognostic value of routine laboratory variables in prediction of breast cancer recurrence. [PDF]

, 2017
The prognostic value of routine laboratory variables in breast cancer has been largely overlooked. Based on laboratory tests commonly performed in clinical practice, we aimed to develop a new model to predict disease free survival (DFS) after surgical ...
Du, Ye, Fan, Zhimin, Fu, Tong, Li, Ke, Li, Ling, Shi, Aiping, Wang, Chun, Wu, Di, Ye, Zhong, Zhu, Yifan, Zhu, Zhu   +10 more
core   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

DNA Repair Deficiency Associated with Hematological Neoplasms

, 2011
The genome of living organisms is constantly subjected to conditions that induce damage to DNA. A wide variety of DNA lesions are produced either as the result of normal metabolic processes or exogenous sources (ionizing radiation, UV light) (Seviour and Lin 2010).
Economopoulou, Panagiota, Pappa, Vassiliki, Papageorgiou, Sotirios, Dervenoulas, John, Economopoulos, Theofanis   +4 more
openaire   +3 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Osteochondroma in a young cat infected by feline leukemia virus

Ciência Rural
: Osteochondromas are primary bone tumors characterized by cartilage-covered bone projections involving single or multiple masses (osteochondromatosis).
Matheus de Oliveira Reis, Lauren Santos de Mello, Kivia Lunardelli Hesse, Marina Paula Lorenzett, Kauê Danilo Helene Lemos dos Reis, Fabrício Souza Campos, Paulo Michel Roehe, Saulo Petinatti Pavarini   +7 more
doaj   +1 more source

Clonal Composition of Human Adrenocortical Neoplasms [PDF]

, 1994
The mechanisms of tumorigenesis of adrenocortical neoplasms are still not understood. Tumor formation may be the result of spontaneous transformation of adrenocortical cells by somatic mutations.
Abdelhamid, S., Allolio, B., Beuschlein, Felix, Chrousos, G. P., Jaursch-Hancke, C., Karl, M., Reincke, Martin, Travis, W.   +7 more
core  

Adenomatoid tumors of the male and female genital tract are defined by TRAF7 mutations that drive aberrant NF-kB pathway activation. [PDF]

, 2018
Adenomatoid tumors are the most common neoplasm of the epididymis, and histologically similar adenomatoid tumors also commonly arise in the uterus and fallopian tube.
Bastian, Boris C, Garg, Karuna, Goode, Benjamin, Grenert, James P, Joseph, Nancy M, Onodera, Courtney, Phillips, Joanna J, Rabban, Joseph T, Solomon, David A, Stevers, Meredith, Talevich, Eric, Van Ziffle, Jessica, Yeh, Iwei, Zaloudek, Charles   +13 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Pancreatic cysts suspected to be branch duct intraductal papillary mucinous neoplasm without concerning features have low risk for development of pancreatic cancer. [PDF]

, 2015
BackgroundThe risk of developing pancreatic cancer is uncertain in patients with clinically suspected branch duct intraductal papillary mucinous neoplasm (BD-IPMN) based on the "high-risk stigmata" or "worrisome features" criteria proposed in the 2012 ...
Fehmi, Syed A, Giap, Andrew Q, Gonzalez, Ingrid, Hunt, Gordon C, Krinsky, Mary L, Kwong, Wilson T, Lawson, Robert D, Savides, Thomas J, Slezak, Jeff, Tang, Raymond S   +9 more
core   +1 more source