Results 61 to 70 of about 479,747 (308)

Cerebellar liponeurocytoma in an elderly patient: DNA methylation profiling as a helpful diagnostic tool

, 2022
Aim: Cerebellar liponeurocytoma is a rare primary cerebellar neoplasm that mostly occurs in adults, however, it is rare in the elderly. Materials and methods: We report, in a 79-year-old female, a recurrent vermian cerebellar mass that was previously ...
Abuelhaija Y., Broggi G., Al-Arman L. Y., Banihani D., Gaggero G., Miele E., Piol N., Alzoubi H., Najadat A. A., Giangaspero F., Gianno F., Fiaschi P., Al-Arman A. Y., Mustafa A., Abualdahab N.   +14 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Osteochondroma in a young cat infected by feline leukemia virus

Ciência Rural
: Osteochondromas are primary bone tumors characterized by cartilage-covered bone projections involving single or multiple masses (osteochondromatosis).
Matheus de Oliveira Reis, Lauren Santos de Mello, Kivia Lunardelli Hesse, Marina Paula Lorenzett, Kauê Danilo Helene Lemos dos Reis, Fabrício Souza Campos, Paulo Michel Roehe, Saulo Petinatti Pavarini   +7 more
doaj   +1 more source

Primary carcinoid tumor of the testis: immunohistochemical, ultrastructural and DNA flow cytometric study of two cases

, 1999
Primary testicular carcinoid tumor, occupying 0.23% of testicular neoplasm, is a rare and indolent neoplasm with the potential for distant metastasis. We present two cases of primary pure carcinoid tumor of the testis.
박영년
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Blastic plasmacytoid dendritic cell neoplasm: From the origin of the cell to targeted therapies; Review

, 2016
International audienceBlastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematological malignancy with an aggressive clinical course. It is grouped with acute myeloid leukemia–related precursor neoplasms in the 2008 World Health Organization ...
Baugier de Materre, Alix, Pierre, Lemaire, Jonathan, Farhi, Kamel, Laribi, Anne, Besançon, Jeremy, Sandrini, Habib, Ghnaya, Catherine, Truong, Nathalie, Denizon   +8 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

The influence of methyl donor status on cervical cancer cell behaviour in vitro [PDF]

, 2013
Epidemiological studies suggest that the availability of methyl-donor nutrients may influence the risk of cervical cancer and of cancer progression. This effect may be mediated by altered DNA instability and aberrant DNA methylation.
Poomipark, Natwadee
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Higher methylation subtype of malignant melanoma and its correlation with thicker progression and worse prognosis

Cancer Medicine, 2020
Malignant melanoma (MM) is the most life‐threatening disease among all skin malignancies, and recent genome‐wide studies reported BRAF, RAS, and NF1 as the most frequently mutated driver genes.
Yosuke Yamamoto, Keisuke Matsusaka, Masaki Fukuyo, Bahityar Rahmutulla, Hiroyuki Matsue, Atsushi Kaneda   +5 more
doaj   +1 more source