Results 41 to 50 of about 479,747 (308)

UV-induced fragmentation of Cajal bodies [PDF]

, 2006
The morphology and composition of subnuclear organelles, such as Cajal bodies (CBs), nucleoli, and other nuclear bodies, is dynamic and can change in response to a variety of cell stimuli, including stress.
Angus I. Lamond, Boulon, Severine, Séverine Boulon, Matera, A. Gregory, Cioce, Mario, Mario Cioce, A. Gregory Matera, Lamond, Angus I.; id_orcid   +7 more
core   +1 more source

Helicobacter pylori is undetectable in intraductal papillary mucinous neoplasm

, 2016
Background: About half of the world population is infected with Helicobacter pylori (H. pylori), a bacterium associated with gastric cancer and considered to be a risk factor for pancreatic ductal adenocarcinoma.
BAĞCI ÇULÇİ, PELİN, ÇELİKEL, ÇİĞDEM   +1 more
core   +1 more source

Chromosomal in situ suppression hybridization of immunologically classified mitotic cells in hematologic malignancies [PDF]

, 1992
Chromosomal in situ suppression (CISS) hybridization was performed with library DNA from sorted human chromosomes 8, 9, 15, 17, 21, and 22 on immunologically stained bone marrow cells of four patients with a hematologic neoplasm, including two patients ...
Knuutila, Sakari, Jotterand Bellomo, Martine, Marianne Tiainen, Tiainen, Marianne, Sakari Knuutila, Tapani Ruutu, Emmerich, Patricia, Cremer, Thomas, Susanne Popp, Martine Jotterand Bellomo, Ruutu, Tapani, Parlier, Valerie, Patricia Emmerich, Popp, Susanne, Thomas Cremer, Valerie Parlier   +15 more
core   +1 more source

Copy number variations in urine cell-free DNA from bladder neoplasm patients

Molecular and Cellular Probes
Bladder cancer is a common malignancy, and its diagnosis is based on invasive procedures such as cystoscopy. Genetic aberrations play an important role in the development of many diseases, including bladder cancer.
Cuello Garcia Haider, Qichao Wang, Guangyue Wang, Yinfeng Wang, Yutong Fu, Zhoufan Zhang, Changling Cao, Fengcheng Xue, Haitao Liu, Qian Wang, Jie Zhou, Tingya Jiang, Jingyi Cao, Yang Zhou   +13 more
doaj   +1 more source

Co-occurrence and Mutual Exclusivity Analysis of DNA Methylation Reveals Distinct Subtypes in Multiple Cancers

Frontiers in Cell and Developmental Biology, 2020
Co-occurrence and mutual exclusivity (COME) of DNA methylation refer to two or more genes that tend to be positively or negatively correlated in DNA methylation among different samples.
Wubin Ding, Guoshuang Feng, Yige Hu, Geng Chen, Tieliu Shi, Tieliu Shi, Tieliu Shi   +6 more
doaj   +1 more source

Association between mitochondrial DNA copy number and high viral load in women with high-risk human papillomavirus [PDF]

, 2023
The infection that most often leads to cervical cancer is human papillomavirus (HPV) infection. A sign that the HPV infection might develop into cancer is mitochondrial dysfunction and DNA damage.
Abbas H.H. AlBosale, Mashkina, E. V.
core  

Integrated Clinical Genotype-Phenotype Characteristics of Blastic Plasmacytoid Dendritic Cell Neoplasm

, 2021
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare, aggressive neoplasm derived from plasmacytoid dendritic cells. While advances in understanding the pathophysiology of the disease have been made, integrated systematic analyses of the ...
M. James You, Omar Alswailmi, C. Cameron Yin, Naveen Pemmaraju, Muzaffar H. Qazilbash, Zhenya Tang, Shaoying Li, Kapil N. Bhalla, Jie Xu, Wei Wang, Joseph D. Khoury, Marina Konopleva   +11 more
core   +1 more source

DNA Methylation-Based Classification of Kidney Neoplasms

Modern Pathology
Renal neoplasms are morphologically and molecularly heterogeneous, with their diagnosis often hindered by interobserver variability and overlapping microscopic features. A subset of cases is unclassifiable despite immunohistochemical, mutation, and cytogenetic-based diagnostic workup. Through examination of the genome-wide DNA methylation signatures of
Papanicolau-Sengos, Antonios, Singh, Omkar, Park, Kyung, Snuderl, Matija, Tretiakova, Maria, Merino, Maria, Stohr, Bradley, Simko, Jeff, Deng, Fang-Ming, Chan, Emily, Wu, Jasper, Barreto, Jairo, Gupta, Rohit, Park, Brian, Turakulov, Rust, Abdullaev, Zied, Solomon, David, Aldape, Kenneth   +17 more
openaire   +2 more sources

Spontaneous and Radiation-Induced Chromosome Aberrations in Primary Fibroblasts of Patients With Pediatric First and Second Neoplasms

Frontiers in Oncology, 2020
The purpose of the present study was to investigate whether former childhood cancer patients who developed a subsequent secondary primary neoplasm (SPN) are characterized by elevated spontaneous chromosomal instability or cellular and chromosomal ...
Sebastian Zahnreich, Alicia Poplawski, Carola Hartel, Lukas Stefan Eckhard, Danuta Galetzka, Thomas Hankeln, Markus Löbrich, Manuela Marron, Johanna Mirsch, Sylvia Ritter, Peter Scholz-Kreisel, Claudia Spix, Heinz Schmidberger   +12 more
doaj   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source