Results 21 to 30 of about 2,091,584 (306)
Synthesis and Antitumor Activity of a GSH Inert Bisphosphonate Platinum (II) Complex
Journal of Chemistry, 2022 Osteosarcoma is a highly aggressive neoplasm. Traditional platinum chemotherapeutic agents for osteosarcoma inevitably have acquired drug resistance and serious side effects, which have limited their utility.
Lu Ma +7 more
doaj +1 more source
DNA replication is required for the checkpoint response to damaged DNA in Xenopus egg extracts. [PDF]
, 2002 Alkylating agents, such as methyl methanesulfonate (MMS), damage DNA and activate the DNA damage checkpoint. Although many of the checkpoint proteins that transduce damage signals have been identified and characterized, the mechanism that senses the ...
Lindsay, Howard D. +3 more
core +4 more sources
Frontiers in Bioengineering and Biotechnology, 2021 Here we show that surface-enhanced Raman scattering (SERS) analysis captures the relative hypomethylation of DNA from patients with acute leukemia associated with Down syndrome (AL-DS) compared with patients diagnosed with transient leukemia associated ...
Vlad Moisoiu +24 more
doaj +1 more source
Human Pathology Reports, 2022 It is generally accepted that choriocarcinoma is a trophoblastic tumor of gestational origin during the reproductive period, but this neoplasm can rarely occur after menopause or be non-gestational making diagnosis a real challenge.
Alina Magnaeva +4 more
doaj +1 more source
Primary Bartholin Adenocarcinoma: a Rare Case and Radiotherapy as Definitive Treatment [PDF]
Folia Medica, 2021 Primary vulvar adenocarcinoma is a very rare neoplasm, accounting for only 1% of all gynecologic malignancies. Most of the glandular carcinomas originated from the Bartholin’s gland.
Lokot Donna Lubis +2 more
doaj +3 more sources
Classification of Colon Cancer Patients Based on the Methylation Patterns of Promoters [PDF]
Genomics & Informatics, 2016 Diverse somatic mutations have been reported to serve as cancer drivers. Recently, it has also been reported that epigenetic regulation is closely related to cancer development. However, the effect of epigenetic changes on cancer is still elusive.
Wonyoung Choi +5 more
doaj +1 more source
Association between mitochondrial DNA copy number and high viral load in women with high-risk human papillomavirus [PDF]
, 2023 The infection that most often leads to cervical cancer is human papillomavirus (HPV) infection. A sign that the HPV infection might develop into cancer is mitochondrial dysfunction and DNA damage.
Abbas H.H. AlBosale, Mashkina, E. V.
core
Electronic transport in DNA [PDF]
, 2008 We study the electronic properties of DNA by way of a tight-binding model applied to four particular DNA sequences. The charge transfer properties are presented in terms of localization lengths (crudely speaking, the length over which electrons travel).
Klotsa, Daphne +2 more
core +1 more source
DNA FISH Diagnostic Assay on Cytological Samples of Thyroid Follicular Neoplasms [PDF]
Cancers, 2020 Although fine-needle aspiration cytology (FNAC) is helpful in determining whether thyroid nodules are benign or malignant, this distinction remains a cytological challenge in follicular neoplasms. Identification of genomic alterations in cytological specimens with direct and routine techniques would therefore have great clinical value.
Philippe Vielh +18 more
openaire +2 more sources