Results 21 to 30 of about 480,652 (268)

Primary Bartholin Adenocarcinoma: a Rare Case and Radiotherapy as Definitive Treatment [PDF]

open access: yesFolia Medica, 2021
Primary vulvar adenocarcinoma is a very rare neoplasm, accounting for only 1% of all gynecologic malignancies. Most of the glandular carcinomas originated from the Bartholin’s gland.
Lokot Donna Lubis   +2 more
doaj   +3 more sources

Classification of Colon Cancer Patients Based on the Methylation Patterns of Promoters [PDF]

open access: yesGenomics & Informatics, 2016
Diverse somatic mutations have been reported to serve as cancer drivers. Recently, it has also been reported that epigenetic regulation is closely related to cancer development. However, the effect of epigenetic changes on cancer is still elusive.
Wonyoung Choi   +5 more
doaj   +1 more source

DNA FISH Diagnostic Assay on Cytological Samples of Thyroid Follicular Neoplasms [PDF]

open access: yesCancers, 2020
Although fine-needle aspiration cytology (FNAC) is helpful in determining whether thyroid nodules are benign or malignant, this distinction remains a cytological challenge in follicular neoplasms. Identification of genomic alterations in cytological specimens with direct and routine techniques would therefore have great clinical value.
Philippe Vielh   +18 more
openaire   +2 more sources

Dependence of DNA-Histograms on The Sampling Techniques in Fine Needle Aspirates of the Breast

open access: yesAnalytical Cellular Pathology, 2002
48 fine needle aspiration biopsy (FNAB) samples from 25 breast cancer cases, originally used for cytodiagnosis were subjected to DNA cytometry. There were air dried smears stained with the MGG method, and samples stained with HE or PAP stain after 50 ...
A. Elzagheid, Y. Collan
doaj   +1 more source

miR-18a reactivates the Epstein-Barr virus through defective DNA damage response and promotes genomic instability in EBV-associated lymphomas

open access: yesBMC Cancer, 2018
Background The Epstein-Barr virus (EBV) is closely associated with several types of malignancies. EBV is normally present in the latent state in the peripheral blood B cell compartment.
Pengfei Cao   +11 more
doaj   +1 more source

Atypical fibroxanthoma: An unusual skin neoplasm in xeroderma pigmentosum

open access: yesIndian Journal of Dermatology, 2012
Xeroderma pigmentosum (XP) is a rare autosomal recessive disorder related to defective deoxyribonucleic acid (DNA) repair. Various cutaneous manifestations related to ultraviolet (UV) damage characterize the clinical course.
Ranjana Bandyopadhyay   +3 more
doaj   +1 more source

Copy number variations in urine cell-free DNA from bladder neoplasm patients

open access: yesMolecular and Cellular Probes
Bladder cancer is a common malignancy, and its diagnosis is based on invasive procedures such as cystoscopy. Genetic aberrations play an important role in the development of many diseases, including bladder cancer.
Cuello Garcia Haider   +13 more
doaj   +1 more source

Co-occurrence and Mutual Exclusivity Analysis of DNA Methylation Reveals Distinct Subtypes in Multiple Cancers

open access: yesFrontiers in Cell and Developmental Biology, 2020
Co-occurrence and mutual exclusivity (COME) of DNA methylation refer to two or more genes that tend to be positively or negatively correlated in DNA methylation among different samples.
Wubin Ding   +6 more
doaj   +1 more source

DNA Methylation-Based Classification of Kidney Neoplasms

open access: yesModern Pathology
Renal neoplasms are morphologically and molecularly heterogeneous, with their diagnosis often hindered by interobserver variability and overlapping microscopic features. A subset of cases is unclassifiable despite immunohistochemical, mutation, and cytogenetic-based diagnostic workup. Through examination of the genome-wide DNA methylation signatures of
Papanicolau-Sengos, Antonios   +17 more
openaire   +2 more sources

Genomic Diversity and Clinical Variability in Pediatric Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Series

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger   +7 more
wiley   +1 more source

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