DNA FISH Diagnostic Assay on Cytological Samples of Thyroid Follicular Neoplasms [PDF]
Although fine-needle aspiration cytology (FNAC) is helpful in determining whether thyroid nodules are benign or malignant, this distinction remains a cytological challenge in follicular neoplasms. Identification of genomic alterations in cytological specimens with direct and routine techniques would therefore have great clinical value.
Philippe Vielh+18 more
openaire +2 more sources
Primary Bartholin Adenocarcinoma: a Rare Case and Radiotherapy as Definitive Treatment [PDF]
Primary vulvar adenocarcinoma is a very rare neoplasm, accounting for only 1% of all gynecologic malignancies. Most of the glandular carcinomas originated from the Bartholin’s gland.
Lokot Donna Lubis+2 more
doaj +3 more sources
Synthesis and Antitumor Activity of a GSH Inert Bisphosphonate Platinum (II) Complex
Osteosarcoma is a highly aggressive neoplasm. Traditional platinum chemotherapeutic agents for osteosarcoma inevitably have acquired drug resistance and serious side effects, which have limited their utility.
Lu Ma+7 more
doaj +1 more source
Frequency and significance of Ras, Tert promoter, and Braf mutations in cytologically indeterminate thyroid nodules: A monocentric case series at a tertiary-level Endocrinology unit [PDF]
PurposeThe management of thyroid nodules of indeterminate cytology is controversial. Our study aimed to establish the frequency and significance of H-,K-,N-RAS, TERT promoter, and BRAF gene mutations in thyroid nodes of indeterminate cytology and to ...
Barollo, Susi+13 more
core +2 more sources
A Comprehensive Microarray-Based DNA Methylation Study of 367 Hematological Neoplasms [PDF]
Alterations in the DNA methylation pattern are a hallmark of leukemias and lymphomas. However, most epigenetic studies in hematologic neoplasms (HNs) have focused either on the analysis of few candidate genes or many genes and few HN entities, and comprehensive studies are required.Here, we report for the first time a microarray-based DNA methylation ...
Martin-Subero, Jose Ignacio+34 more
openaire +9 more sources
TUBA1A-GLI1 fusion in a soft tissue myoepithelial neoplasm
Several types of benign and malignant neoplasms harboring GLI1 gene fusions with various partner genes, including ACTB, MALAT1 and PTCH1, have been described.
Yajuan J. Liu+3 more
doaj
Detection of human papillomavirus DNA in intraosseus ameloblastoma [PDF]
Human Papillomavirus (HPV) infection has been shown as a risk factor in oral carcinogenesis. The association between HPV and benign and malignant neoplasm of oral mucosa, especially surface epithelium-derived tumors, is well established.
Khodayari-Nemin, A.+5 more
core +1 more source
Classification of Colon Cancer Patients Based on the Methylation Patterns of Promoters [PDF]
Diverse somatic mutations have been reported to serve as cancer drivers. Recently, it has also been reported that epigenetic regulation is closely related to cancer development. However, the effect of epigenetic changes on cancer is still elusive.
Wonyoung Choi+5 more
doaj +1 more source
Cancer in Ancient Human Populations: Methods and Practice in Bioarchaeology and Paleopathology [PDF]
Best Undergraduate Writing in Anthropology Award, 2019-2020Despite its prevalence in contemporary public health, research on the paleopathology of cancer is still extremely limited.
Gardner, Elijah
core
Mucosal nasopharyngeal melanoma is a rare head and neck melanoma. Prognosis is poor (5-year overall survival rate of 10–30%) with high rates of metastases and local recurrence. Head and neck mucosal melanoma represents 0.8–3.7% of all melanomas and 0.03%
Calvieri, Stefano+4 more
core +1 more source