Results 21 to 30 of about 2,773,935 (245)

Targeted DNA Sequencing Reveals Patterns of Local Progression in the Pancreatic Remnant Following Resection of Intraductal Papillary Mucinous Neoplasm (IPMN) of the Pancreas

open access: yesAnnals of Surgery, 2017
Objective: The aim of this study was to characterize patterns of local progression following resection for pancreatic intraductal papillary mucinous neoplasms (IPMN) using targeted next-generation sequencing (NGS).
A. Pea   +19 more
semanticscholar   +1 more source

Circulating Tumor DNA Analyses as Markers of Recurrence Risk and Benefit of Adjuvant Therapy for Stage III Colon Cancer.

open access: yesJAMA Oncology, 2019
Importance Adjuvant chemotherapy in patients with stage III colon cancer prevents recurrence by eradicating minimal residual disease. However, which patients remain at high risk of recurrence after completing standard adjuvant treatment cannot currently ...
J. Tie   +23 more
semanticscholar   +1 more source

Synthesis and Antitumor Activity of a GSH Inert Bisphosphonate Platinum (II) Complex

open access: yesJournal of Chemistry, 2022
Osteosarcoma is a highly aggressive neoplasm. Traditional platinum chemotherapeutic agents for osteosarcoma inevitably have acquired drug resistance and serious side effects, which have limited their utility.
Lu Ma   +7 more
doaj   +1 more source

SERS-Based Evaluation of the DNA Methylation Pattern Associated With Progression in Clonal Leukemogenesis of Down Syndrome

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Here we show that surface-enhanced Raman scattering (SERS) analysis captures the relative hypomethylation of DNA from patients with acute leukemia associated with Down syndrome (AL-DS) compared with patients diagnosed with transient leukemia associated ...
Vlad Moisoiu   +24 more
doaj   +1 more source

Non-gestational choriocarcinoma of ovary: Clinico-morphological features and diagnostic value of DNA polymorphism study

open access: yesHuman Pathology Reports, 2022
It is generally accepted that choriocarcinoma is a trophoblastic tumor of gestational origin during the reproductive period, but this neoplasm can rarely occur after menopause or be non-gestational making diagnosis a real challenge.
Alina Magnaeva   +4 more
doaj   +1 more source

Primary Bartholin Adenocarcinoma: a Rare Case and Radiotherapy as Definitive Treatment [PDF]

open access: yesFolia Medica, 2021
Primary vulvar adenocarcinoma is a very rare neoplasm, accounting for only 1% of all gynecologic malignancies. Most of the glandular carcinomas originated from the Bartholin’s gland.
Lokot Donna Lubis   +2 more
doaj   +3 more sources

Classification of Colon Cancer Patients Based on the Methylation Patterns of Promoters [PDF]

open access: yesGenomics & Informatics, 2016
Diverse somatic mutations have been reported to serve as cancer drivers. Recently, it has also been reported that epigenetic regulation is closely related to cancer development. However, the effect of epigenetic changes on cancer is still elusive.
Wonyoung Choi   +5 more
doaj   +1 more source

Dependence of DNA-Histograms on The Sampling Techniques in Fine Needle Aspirates of the Breast

open access: yesAnalytical Cellular Pathology, 2002
48 fine needle aspiration biopsy (FNAB) samples from 25 breast cancer cases, originally used for cytodiagnosis were subjected to DNA cytometry. There were air dried smears stained with the MGG method, and samples stained with HE or PAP stain after 50 ...
A. Elzagheid, Y. Collan
doaj   +1 more source

miR-18a reactivates the Epstein-Barr virus through defective DNA damage response and promotes genomic instability in EBV-associated lymphomas

open access: yesBMC Cancer, 2018
Background The Epstein-Barr virus (EBV) is closely associated with several types of malignancies. EBV is normally present in the latent state in the peripheral blood B cell compartment.
Pengfei Cao   +11 more
doaj   +1 more source

Atypical fibroxanthoma: An unusual skin neoplasm in xeroderma pigmentosum

open access: yesIndian Journal of Dermatology, 2012
Xeroderma pigmentosum (XP) is a rare autosomal recessive disorder related to defective deoxyribonucleic acid (DNA) repair. Various cutaneous manifestations related to ultraviolet (UV) damage characterize the clinical course.
Ranjana Bandyopadhyay   +3 more
doaj   +1 more source

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