Ancient and novel small RNA pathways compensate for the loss of piRNAs in multiple independent nematode lineages. [PDF]
PLoS Biology, 2015 Small RNA pathways act at the front line of defence against transposable elements across the Eukaryota. In animals, Piwi interacting small RNAs (piRNAs) are a crucial arm of this defence.
Peter Sarkies +14 more
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Frontiers in Plant Science, 2021 Mediator is a conserved multiprotein complex important for transcription by RNA polymerase II (Pol II). Arabidopsis Mediator subunit MED18 regulates flowering, hormone signaling and plant immunity.
Yan Zhang +6 more
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AGO6 functions in RNA-mediated transcriptional gene silencing in shoot and root meristems in Arabidopsis thaliana. [PDF]
PLoS ONE, 2011 RNA-directed DNA methylation (RdDM) is a small interfering RNA (siRNA)-mediated epigenetic modification that contributes to transposon silencing in plants. RdDM requires a complex transcriptional machinery that includes specialized RNA polymerases, named
Changho Eun +8 more
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A Bayesian approach to analyse genetic variation within RNA viral populations. [PDF]
PLoS Computational Biology, 2011 The development of modern and affordable sequencing technologies has allowed the study of viral populations to an unprecedented depth. This is of particular interest for the study of within-host RNA viral populations, where variation due to error-prone ...
Trevelyan J McKinley +4 more
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Essential Oils Prime Epigenetic and Metabolomic Changes in Tomato Defense Against Fusarium oxysporum
Frontiers in Plant Science, 2022 In this work, we studied the direct and indirect plant protection effects of an Artemisia absinthium essential oil (AEO) on tomato seedlings against Fusarium oxysporum sp. oxysporum radicis lycopersici (Fol). AEO exhibited a toxic effect in vitro against
Serine Soudani +5 more
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Novel endoribonucleases as central players in various pathways of eukaryotic RNA metabolism [PDF]
, 2010 For a long time it has been assumed that the decay of RNA in eukaryotes is mainly carried out by exoribonucleases, which is in contrast to bacteria, where endoribonucleases are well documented to initiate RNA degradation.
Tomecki, Rafał, Dziembowski, Andrzej
core +3 more sources
RNA-specific ribonucleotidyl transferases [PDF]
, 2007 RNA-specific nucleotidyl transferases (rNTrs) are a diverse family of template-independent polymerases that add ribonucleotides to the 3'-ends of RNA molecules.
Keller, W. +3 more
core +1 more source
Functional Consequences of Subunit Diversity in RNA Polymerases II and V
Cell Reports, 2012 Multisubunit RNA polymerases IV and V (Pol IV and Pol V) evolved as specialized forms of Pol II that mediate RNA-directed DNA methylation (RdDM) and transcriptional silencing of transposons, viruses, and endogenous repeats in plants.
Ek Han Tan +3 more
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Use of Site-Specifically Tethered Chemical Nucleases to Study Macromolecular Reactions
Biological Procedures Online, 2003 During a complex macromolecular reaction multiple changes in molecular conformation and interactions with ligands may occur. X-ray crystallography may provide only a limited set of snapshots of these changes.
Mukherjee Srabani, Sousa Rui
doaj +1 more source
RNase-like domain in DNA-directed RNA polymerase II. [PDF]
Proceedings of the National Academy of Sciences, 1991 DNA-directed RNA polymerase is responsible for gene expression. Despite its importance, many details of its function and higher-order structure still remain unknown. We report here a local sequence similarity between the second largest subunit of RNA polymerase II and bacterial RNases Ba (barnase), Bi, and St. The most remarkable similarity is that the
T, Shirai, M, Go
openaire +2 more sources