Results 211 to 220 of about 1,846,477 (392)

Ubc13/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage

, 2007
Bin Wang, Stephen J. Elledge
openalex   +2 more sources

Targeting the DNA Damage Response in Cancer.

Molecules and Cells, 2015
M. O’Connor
semanticscholar   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

Identifying a role for Ciz1 in the DNA damage response [PDF]

, 2011
Katherine Roper
openalex  

Supplementary Figure S4 from Suppression of <i>CHK1</i> by ETS Family Members Promotes DNA Damage Response Bypass and Tumorigenesis [PDF]

, 2023
Andrea Lunardi, Shohreh Varmeh, Ming Chen, Riccardo Taulli, Jlenia Guarnerio, Ugo Ala, Nina Seitzer, Tomoki Ishikawa, Brett S. Carver, Robin M. Hobbs, Valentina Quarantotti, Christopher Ng, Alice H. Berger, Caterina Nardella, Laura Poliseno, Rodolfo Montironi, Mireia Castillo-Martín, Carlos Cordon‐Cardo, Sabina Signoretti, Pier Paolo Pandolfi   +19 more
openalex   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

DNA damage-induced immune response: Micronuclei provide key platform [PDF]

, 2017
Nelson O. Gekara
openalex   +1 more source

Supplementary Figure 1 from Multicellular complex tumor spheroid response to DNA repair inhibitors in combination with DNA-damaging drugs [PDF]

, 2023
Thomas S. Dexheimer, Nathan P. Coussens, Thomas Silvers, John Wright, Joel Morris, James H. Doroshow, Beverly A. Teicher   +6 more
openalex   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source