Results 231 to 240 of about 671,892 (268)

Coilin and SUMOylation influence PARP1 dynamics and the DNA damage response.

J Cell Sci
Tucker SK, Seale BC, Brown DT, Hebert MD.   +3 more
europepmc   +1 more source

TRIP12's role in the governance of DNA polymerase β involvement in DNA damage response and repair. [PDF]

Nucleic Acids Res
Inanc B, Fang Q, Roos WP, Andrews JF, Zeng X, Clark J, Li J, Dey NB, Ibrahim M, Sykora P, Yu Z, Pearson CR, Braganza A, Verheij M, Jonkers J, Yates NA, Vens C, Sobol RW.   +17 more
europepmc   +1 more source

Nanoparticles Decorated Nanotubes: Advanced Local Therapies From Anodized Nanoengineered Titanium Implants

Advanced Functional Materials, EarlyView.
This comprehensive review explores therapeutic titanium implants designed to enhance integration and provide superior antibacterial efficacy. It is focused on anodized titanium implants with titania nanotubes (TNTs) loaded with nanoparticles (NPs) for local therapeutic release, enhancing bioactivity and bactericidal functions.
Divya Chopra, Liwen Zhang, Tianqi Guo, Sašo Ivanovski, Ruirui Qiao, Karan Gulati   +5 more
wiley   +1 more source

WTAP participates in the DNA damage response via an m⁶A-FOXM1-dependent manner in hepatocellular carcinoma. [PDF]

Cell Death Discov
Huang N, Bian Z, Xu C, Zhang Y, Liu L, Cui Z, Zhao S, Fan Q, Xue S, Chen Y, Pan Q, Sun F.   +11 more
europepmc   +1 more source

CRISPR/Cas9‐Assisted Microrobots for Fast and Ultrasensitive “On‐The‐Fly” Next‐Generation DNA Detection

Advanced Functional Materials, EarlyView.
This work presents self‐propelled CRISPR/Cas9‐functionalized Au–MRs for rapid, amplification‐free, “on‐the‐fly” DNA detection. By harnessing motion‐assisted signal recovery, the platform achieved the limit of detection in low fM DNA concentrations, enabling detection across a wide dynamic range within only 5 min, which is significantly faster than any ...
Jyoti, Petr Michálek, Zbyněk Heger, Martin Pumera   +3 more
wiley   +1 more source

Nucleolar stress facilitates islet β cell senescence via hijacking the DNA damage response pathways. [PDF]

iScience
Jiao Y, Lu W, Wang X, Sun W, Hu B, Zhao J, Fang J, Lu Y, Wan C.   +8 more
europepmc   +1 more source

Integrated Metallo‐Dielectric 3D Hotspots From High Refractive Index Nanodiamond‐Plasmonic Gold Cryosoret Nano‐Assemblies for Photonic Crystal Enhanced Fluorescence

Advanced Functional Materials, EarlyView.
This work presents a novel sensing platform using metallo‐dielectric cryosoret nano‐assemblies and lossless photonic crystals to overcome limitations of conventional plasmonic biosensors. The hybrid system enhances both electric and magnetic field interactions, enabling amplified fluorescence, ultralow detection limits, and prism‐free, objective‐free ...
Seemesh Bhaskar, Weinan Liu, Skye Shepherd, Devinda Wijewardena, Joseph Tibbs, Brian T. Cunningham   +5 more
wiley   +1 more source

Interplay and Dynamics of Chromatin Architecture and DNA Damage Response: An Overview. [PDF]

Cancers (Basel)
Ambrosio S, Noviello A, Di Fusco G, Gorini F, Piscone A, Amente S, Majello B.   +6 more
europepmc   +1 more source

Reconfigurable Microenvironments Uncover Mechano‐Sensing Timescales and Direct Cell Polarity

Advanced Functional Materials, EarlyView.
A synthetic DNA‐crosslinked cell culture matrix enables control over the mechanical microenvironment surrounding cells. Independent tuning of stiffness and stress relaxation uncovers distinct timescales of mechano‐sensing that regulate cell behavior.
Syuan‐Ku Hsiao, Markus Mukenhirn, Carsten Werner, Alf Honigmann, Elisha Krieg   +4 more
wiley   +1 more source

Association of DNA damage response pathway genes with rheumatoid arthritis risks: a case-control study. [PDF]

Sci Rep
Hussain MZ, Khan MH, Haris MS, Huzaira R, Munawar A, Haq MFU, Shafique R, Mahjabeen I.   +7 more
europepmc   +1 more source