Results 41 to 50 of about 2,368,060 (250)
Genome editing to the rescue: sustainably feeding 10 billion global human population [PDF]
, 2016 Modern animal breeding strategies based on population genetics, molecular tools,artificial insemination,embryo transfer and related technologies have contributed to significant increases in the performance of domestic animals, and are the basis for a ...
Whitelaw, C. B. A. +11 more
core +1 more source
, 2023 The advancement of precision engineering for crop trait improvement is important in the face of rapid population growth, climate change, and disease. To this end, targeted double-stranded break technology using RNA-guided Cas9 has been adopted widely for
Myeong-Je Cho (4031018) +8 more
core +1 more source
Herpesviral lytic gene functions render the viral genome susceptible to novel editing by CRISPR/Cas9
eLife, 2019 Herpes simplex virus (HSV) establishes lifelong latent infection and can cause serious human disease, but current antiviral therapies target lytic but not latent infection.
Hyung Suk Oh +6 more
doaj +1 more source
Molecular Therapy: Nucleic Acids, 2022 Precise genome editing of human pluripotent stem cells (hPSCs) is crucial not only for basic science but also for biomedical applications such as ex vivo stem cell therapy and genetic disease modeling.
Ju-Chan Park +7 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Post-editing machine translated text in a commercial setting: Observation and statistical analysis [PDF]
, 2010 Machine translation systems, when they are used in a commercial context for publishing purposes, are usually used in combination with human post-editing.
Tatsumi, Midori
core +2 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
, 2023 The advancement of precision engineering for crop trait improvement is important in the face of rapid population growth, climate change, and disease. To this end, targeted double-stranded break technology using RNA-guided Cas9 has been adopted widely for
Myeong-Je Cho (4031018) +8 more
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
, 2023 The advancement of precision engineering for crop trait improvement is important in the face of rapid population growth, climate change, and disease. To this end, targeted double-stranded break technology using RNA-guided Cas9 has been adopted widely for
Myeong-Je Cho (4031018) +8 more
core +1 more source