DNA polymerase V activity is autoregulated by a novel intrinsic DNA-dependent ATPase [PDF]
arXiv, 2014 Escherichia coli DNA polymerase V (pol V), a heterotrimeric complex composed of UmuD'2C, is marginally active. ATP and RecA play essential roles in the activation of pol V for DNA synthesis including translesion synthesis (TLS). We have established three features of the roles of ATP and RecA.
arxiv
Transcription‐coupled repair: tangled up in convoluted repair
The FEBS Journal, EarlyView.In this review, we discuss recent findings derived from diverse genomic, biochemical and structural, imaging, and functional studies (B–E) that culminated in deep mechanistic insight (A) into the vital cellular process of transcription‐coupled nucleotide excision repair (TC‐NER).
Diana A. Llerena Schiffmacher +3 more
wiley +1 more source
Mechanism of DNA strand nicking at apurinic/apyrimidinic sites by Escherichia coli [formamidopyrimidine]DNA glycosylase [PDF]
, 1989 V Bailly +3 more
openalex +1 more source
Cell Death and Disease, 2012 Uracil DNA glycosylase (UDG) specifically removes uracil bases from DNA, and its repair activity determines the sensitivity of the cell to anticancer agents that are capable of introducing uracil into DNA.
A. Bulgar +9 more
semanticscholar +1 more source
A Possible Mechanism of DNA to DNA Transcription in Eukaryotic Cells : Endonuclease Dependent Transcript Cutout [PDF]
arXiv, 2016 We previously proposed the existence of DNA to DNA transcription in eukaryotic cells, but the mechanism by which single-stranded DNA (ssDNA) transcript is produced and released from the genome remains unknown. We once speculated that the mechanism of DNA to DNA transcription might be similar to that of DNA to RNA transcription, but now we propose that ...
arxiv
Medical and Veterinary Entomology, EarlyView.We identified Culex pipiens bloodmeals at the species level in natural, agricultural and peri‐urban habitats and calculated host preferences based on forage ratios. This analysis showed Passeriformes, and in particular Columba livia, Passer montanus and Turdus sp., to be the preferred Cx. pipiens hosts.
Víctor Rodríguez‐Valencia +9 more
wiley +1 more source
DNA Sequence Context Effects on the Glycosylase Activity of Human 8-Oxoguanine DNA Glycosylase*
Journal of Biological Chemistry, 2012 Background: Human 8-oxoguanine DNA glycosylase (OGG1) removes the mutagenic DNA lesion 7,8-dihydro-8-oxoguanine. Results: OGG1 activity is significantly decreased by an adjacent DNA mismatch.
A. Sassa +3 more
semanticscholar +1 more source
GCN5‐related histone acetyltransferase HOOKLESS2 regulates fungal resistance and growth in tomato
New Phytologist, Volume 246, Issue 3, Page 1217-1235, May 2025.Summary The functions of histone acetyltransferases (HATs) in the genetic control of crop traits and the underlying mechanisms are poorly understood. We studied the function of tomato HOOKLESS2 (SlHLS2), a member of the GCN5 family of HATs, through genetic, molecular and genomic approaches. Tomato hls2 mutants generated through CRISPR‐cas9 gene editing
Namrata Jaiswal +3 more
wiley +1 more source
Identification of the coding sequence for herpes simplex virus uracil-DNA glycosylase [PDF]
, 1988 Diane M. Worrad, Salvatore J. Caradonna
openalex +1 more source
Engineering an optimized hypercompact CRISPR/Cas12j‐8 system for efficient genome editing in plants
Plant Biotechnology Journal, Volume 23, Issue 4, Page 1153-1164, April 2025.Summary The Cas12j‐8 nuclease, derived from the type V CRISPR system, is approximately half the size of Cas9 and recognizes a 5′‐TTN‐3′ protospacer adjacent motif sequence, thus potentially having broad application in genome editing for crop improvement. However, its editing efficiency remains low in plants. In this study, we rationally engineered both
Shasha Bai +5 more
wiley +1 more source