Results 61 to 70 of about 2,011,431 (260)
Advanced Science, EarlyView.In this work, a detection method is presented for the activity of plasma DNA methyltransferase 1 (DNMT1), namely DNMT1 Identification by Variable Activity (DIVA). DIVA can detect plasma DNMT1 at levels as low as 10−7 U mL−1, also it successfully evaluated tumor burden and predicted the neoadjuvant therapy responses of breast cancer patients.
Yingran Wang +10 more
wiley +1 more source
Specificity and Catalytic Mechanism in Family 5 Uracil DNA Glycosylase*
Journal of Biological Chemistry, 2014 Background: Uracil DNA glycosylases are DNA repair enzymes involved in the removal of base damage. Results: Family 5 UDGb is a uracil, hypoxanthine, and xanthine DNA glycosylase.
B. Xia +5 more
semanticscholar +1 more source
Scientific Reports, 2017 Both a DNA lesion and an intermediate for antibody maturation, uracil is primarily processed by base excision repair (BER), either initiated by uracil-DNA glycosylase (UNG) or by single-strand selective monofunctional uracil DNA glycosylase (SMUG1).
Lene Alsøe +15 more
doaj +1 more source
Capacity of DNA Data Embedding Under Substitution Mutations [PDF]
, 2011 A number of methods have been proposed over the last decade for encoding information using deoxyribonucleic acid (DNA), giving rise to the emerging area of DNA data embedding. Since a DNA sequence is conceptually equivalent to a sequence of quaternary symbols (bases), DNA data embedding (diversely called DNA watermarking or DNA steganography) can be ...
arxiv +1 more source
Thymine DNA Glycosylase Can Rapidly Excise 5-Formylcytosine and 5-Carboxylcytosine
Journal of Biological Chemistry, 2011 Background: Thymine DNA glycosylase is essential for active DNA demethylation and embryonic development. Results: TDG rapidly excises 5-formylcytosine (fC) and 5-carboxylcytosine (caC), products of Tet-mediated oxidation of 5-methylcytosine.
A. Maiti, A. Drohat
semanticscholar +1 more source
BioTechniques, 2022 This study sought to develop a short DNA detection method using a deoxyuridine probe and polymerase chain reaction. The probe was hybridized to the target short DNA, which was then extended by DNA polymerase.
Naoki Harikai +4 more
doaj +1 more source
In Vitro Genotoxicity Assessment of Functional Ingredients: Betaine, Choline, and Taurine
Foods, 2021 This article focuses on a complete in vitro genotoxicity assessment of three nutrients widely used as functional ingredients in the European market: betaine, choline, and taurine.
Julen Sanz-Serrano +4 more
doaj +1 more source
An Update: Enzymatic Synthesis for Industrial Applications
Angewandte Chemie International Edition, EarlyView.Biocatalysis has become a sustainable and cost‐competitive alternative to established chemical synthesis, enabling the enzyme‐based production of not only commodity chemicals but (non‐natural) amino acids, (rare) sugars, as well as synthetic nucleotides.
Thomas Bayer +4 more
wiley +1 more source
Stable transgenerational epigenetic inheritance requires a DNA methylation-sensing circuit
Nature Communications, 2017 DNA methylation patterns are inherited over many generations in plants. Here, Williams and Gehring show that the 5-methylcytosine DNA glycosylase ROS1 functions as part of a methylation-sensitive circuit that ensures long-term epigenetic fidelity in ...
Ben P. Williams, Mary Gehring
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2020 Human telomeres as well as more than 40% of human genes near the promoter regions have been found to contain the sequence that may form a G-quadruplex structure.
Alexandra A. Kuznetsova +4 more
doaj +1 more source