Results 81 to 90 of about 1,564,144 (179)

The RNA moiety of chick embryo 5-methylcytosine- DNA glycosylase targets DNA demethylation [PDF]

, 2017
We have previously shown that DNA demethylation by chick embryo 5-methylcytosine (5-MeC)-DNA glycosylase needs both protein and RNA. RNA from enzyme purified by SDS-PAGE was isolated and cloned.
Siegmann, Michel, Hofsteenge, Jan, Frémont, Marc, Jost, Jean-Pierre   +3 more
core  

A C-HCR assembly of branched DNA nanostructures for amplified uracil-DNA glycosylase assays

, 2017
The amplified and selective detection of uracil-DNA glycosylase was enabled by a two-layered cascaded hybridization chain reaction machinery.
Min Pan, Jie Wei, Xiaoqing Liu, Fuan Wang, Jing Wang   +4 more
core   +1 more source

Genome‐wide association study of morphometric and metabolic characteristics in European populations of the sugar kelp Saccharina latissima

Journal of Phycology, EarlyView.
Abstract The sugar kelp Saccharina latissima is a promising candidate for sustainable aquaculture in the North Atlantic and Northeast Pacific, but genetic improvement has been hindered by a limited understanding of the genetic basis of economically important traits.
Stéphane Mauger, Komlan Avia, Lucie Jaugeon, Paolo Ruggeri, Zofia Nehr, Ousseini Issaka Salia, Jérôme Coudret, Emilie Gouhier, Aurélien Baud, Stéphane Loisel, Antoine Fort, Ronan Sulpice, Christophe Destombe, Philippe Potin, J. Mark Cock, Myriam Valero   +15 more
wiley   +1 more source

Lesion Recognition and Cleavage of Damage-Containing Quadruplexes and Bulged Structures by DNA Glycosylases

Frontiers in Cell and Developmental Biology, 2020
Human telomeres as well as more than 40% of human genes near the promoter regions have been found to contain the sequence that may form a G-quadruplex structure.
Alexandra A. Kuznetsova, Olga S. Fedorova, Olga S. Fedorova, Nikita A. Kuznetsov, Nikita A. Kuznetsov   +4 more
doaj   +1 more source

Three-Dimensional Structure of a DNA Repair Enzyme, 3-Methyladenine DNA Glycosylase II, from Escherichia coli

, 1996
The three-dimensional structure of Escherichia coli 3-methyladenine DNA glycosylase II, which removes numerous alkylated bases from DNA, was solved at 2.3 Å resolution.
Tomita, Ken-ichi, Ihara, Kenji, Fujii, Yoshimitsu, Odawara, Kyoko, Yamagata, Yuriko, Nakabeppu, Yusaku, Yasumura, Kohei, Sekiguchi, Mutsuo, Kato, Masato, Fujii, Satoshi, Nakashima, Yoko, Tokuno, Yoshiteru, Matsushima, Nobuko   +12 more
core   +1 more source

The Cytosolic Iron–Sulfur Cluster Assembly Targeting Complex Is Hijacked by Magnaporthe Effector AvrPi9 to Suppress Rice Resistance

Plant Biotechnology Journal, EarlyView.
ABSTRACT The cytosolic iron–sulfur (Fe‐S) cluster assembly (CIA) targeting complex mediates the maturation of cytosolic and nuclear Fe‐S proteins and governs core eukaryotic cellular processes. However, whether this complex contributes to plant disease resistance remains unclear.
Huanbin Shi, Zhiquan Liu, Ying Zhang, Runjing Li, Zhizhen Fu, Ya Chen, Hui Wen, Liang Cai, Zhengting Chen, Jiehua Qiu, Yanjun Kou   +10 more
wiley   +1 more source

Label-free and sensitive detection of uracil-DNA glycosylase using exponential real-time rolling circle amplification

, 2018
Schematic representation of an exponential rolling circle amplification-based uracil-DNA glycosylase activity-sensing platform.
Qiu-Ge Zhao, De-Ming Kong, Yun-Xi Cui, An-Na Tang, Yuan Xu   +4 more
core   +1 more source

The E3 Ubiquitin Ligase NEDD4L Targets OGG1 for Ubiquitylation and Modulates the Cellular DNA Damage Response

Frontiers in Cell and Developmental Biology, 2020
8-Oxoguanine DNA glycosylase (OGG1) is the major cellular enzyme required for the excision of 8-oxoguanine DNA base lesions in DNA through the base excision repair (BER) pathway, and therefore plays a major role in suppressing mutagenesis and in ...
Jonathan R. Hughes, Jason L. Parsons, Jason L. Parsons   +2 more
doaj   +1 more source

Molecular Links Between Heat Stress and DNA Damage Response in Plants

Plant, Cell &Environment, EarlyView.
ABSTRACT Climate change poses a major threat to agricultural productivity and, consequently, to global food security. Among the consequences of climate change, heat stress (HS) has emerged as a critical factor limiting crop performance. This has stimulated extensive research over the past decade to elucidate the molecular and physiological mechanisms ...
Adrian Calves‐Ubach, Miriam Szurman‐Zubrzycka   +1 more
wiley   +1 more source

Competitive Inhibition of Uracil DNA Glycosylase by a Modified Nucleotide Whose Triphosphate is a Substrate for DNA Polymerase

, 2016
Competitive Inhibition of Uracil DNA Glycosylase by a Modified Nucleotide Whose Triphosphate is a Substrate for DNA ...
Marc M. Greenberg (8794), James T. Stivers (13506), Haidong Huang (500230)   +2 more
core   +1 more source