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Aphid Resistance in Pulse Crops: Sources, Mechanisms, Genetics and Breeding
Legume Science, Volume 8, Issue 4, December 2026.ABSTRACT Aphids are major pests of pulse crops, causing damage through phloem sap feeding and virus transmission. In this context, resistant varieties are central components of sustainable aphid management. This review synthesizes current knowledge on resistance sources, phenotyping strategies, resistance mechanisms, genetic control and breeding ...
Francisco A. Mendes +3 more
wiley +1 more source
, 1995 We have previously shown that in developing chicken embryos and differentiating mouse myoblasts, the demethylation of 5-metCpGs occurs through the replacement of 5-methylcytosine by cytosine (Jost, J. P. (1993) Proc. Natl. Acad. Sci. U.S.A. 90, 4685-4688;
Jost JP, Sun L, Leung R, Siegmann M
core +1 more source
The role of human alkyladenine glycosylase in cellular resistance to the chloroethylnitrosoureas
, 2008 To investigate the possible role of glycosylase action in causing tumor resistance, a full-length, histidine-tagged human alkyladenine glycosylase has been purified from the cloned human gene contained in a pTrc99A vector propagated in a tag alkA mutant ...
Matijasevic, Zdenka +5 more
core +1 more source
Research progress on the role of the NEIL family in cancer
Frontiers in Cell and Developmental BiologyCancer is the primary cause of death worldwide. Cancer occurrence and progression are closely associated with DNA damage repair. DNA glycosylase were the first enzymes to initiate base excision repair, and the Nei-like DNA glycosylase (NEIL) family has ...
Yinghan Chen +4 more
doaj +1 more source
Human cDNA expressing a functional DNA glycosylase excising 3-methyladenine and 7-methylguanine
, 1991 A cDNA expression library from a human cell line was introduced into an E. coli strain deficient in the repair of 3-meAde bases in DNA. E. coli strains deficient in the repair of 3-meAde are unusually sensitive to DNA methylating agents.
O'Connor, Timothy R, Laval, Jacques
core +1 more source
Türk Biyokimya DergisiHuman 8-hydroxy guanine DNA glycosylase (hOGG1) is a DNA repair enzyme associated with hepatocellular carcinoma (HCC). This study aimed to investigate the pooled relationship between hOGG1 rs1052133 polymorphism and HCC susceptibility.
Xu Haomiao +4 more
doaj +1 more source
A common SNP in the UNG gene decreases ovarian cancer risk in BRCA2 mutation carriers
Molecular Oncology, 2019 Single nucleotide polymorphisms (SNPs) in DNA glycosylase genes involved in the base excision repair (BER) pathway can modify breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers.
Juan Miguel Baquero +8 more
doaj +1 more source
Inefficient excision of uracil from loop regions of DNA oligomers by E.coli uracil DNA glycosylase
, 1994 Kinetic parameters for uracil DNA glycosylase (E.coli)-catalysed excision of uracil from DNA oligomers containing dUMP in different structural contexts were determined.
N. Vinay Kumar +5 more
core +1 more source
Berzosertib (VE-822) inhibits gastric cancer cell proliferation via base excision repair system
Cancer Management and Research, 2019 Fubiao Ni,1,* Hengjie Tang,1,* Cheng Wang,1,* Zixiang Wang,2 Fangyi Yu,2 Bicheng Chen,1 Linxiao Sun1 1Key Laboratory of Diagnosis and Treatment of Severe Hepato-Pancreatic Diseases of Zhejiang Province, Zhejiang Provincial Top Key Discipline in Surgery ...
Ni F +6 more
doaj
DNA binding and lesion recognition by the bacterial interstrand DNA crosslink glycosylase AlkX
EMBO ReportsInterstrand DNA crosslinks (ICLs) are a highly toxic form of DNA damage. ICL repair in both eukaryotes and bacteria involves unhooking of the two strands by specialized DNA glycosylases.
Yujuan Cai +5 more
doaj +1 more source