Results 21 to 30 of about 2,038,987 (238)

Potent pollen gene regulation by DNA glycosylases in maize [PDF]

Nature Communications
Although DNA methylation primarily represses TEs, it also represses select genes that are methylated in plant body tissues but demethylated by DNA glycosylases (DNGs) in endosperm or pollen.
Yibing Zeng, Julian Somers, Harrison S. Bell, Zuzana Vejlupkova, R. Kelly Dawe, John E. Fowler, Brad Nelms, Jonathan I. Gent   +7 more
doaj   +2 more sources

Neil DNA glycosylases promote substrate turnover by Tdg during DNA demethylation. [PDF]

Nat Struct Mol Biol, 2016
DNA 5-methylcytosine is a dynamic epigenetic mark with important roles in development and disease. In the Tet-Tdg demethylation pathway, methylated cytosine is iteratively oxidized by Tet dioxygenases, and unmodified cytosine is restored via thymine DNA ...
Schomacher L, Han D, Musheev MU, Arab K, Kienhöfer S, von Seggern A, Niehrs C.   +6 more
europepmc   +2 more sources

DNA glycosylases in the base excision repair of DNA. [PDF]

Biochemical Journal, 1997
A wide range of cytotoxic and mutagenic DNA bases are removed by different DNA glycosylases, which initiate the base excision repair pathway. DNA glycosylases cleave the N-glycosylic bond between the target base and deoxyribose, thus releasing a free base and leaving an apurinic/apyrimidinic (AP) site.
H. Krokan, R. Standal, G. Slupphaug
semanticscholar   +3 more sources

Emerging Roles of DNA Glycosylases and the Base Excision Repair Pathway. [PDF]

Trends Biochem Sci, 2019
Mullins EA, Rodriguez AA, Bradley NP, Eichman BF.   +3 more
europepmc   +2 more sources

Differential Ability of Five DNA Glycosylases to Recognize and Repair Damage on Nucleosomal DNA. [PDF]

ACS Chem Biol, 2017
Olmon ED, Delaney S.
europepmc   +2 more sources

Detection of Uracil-Excising DNA Glycosylases in Cancer Cell Samples Using a Three-Dimensional DNAzyme Walker. [PDF]

ACS Meas Sci Au
Tao J, Zhang H, Weinfeld M, Le XC.
europepmc   +3 more sources

Lesion Recognition and Cleavage of Damage-Containing Quadruplexes and Bulged Structures by DNA Glycosylases. [PDF]

Front Cell Dev Biol, 2020
Kuznetsova AA, Fedorova OS, Kuznetsov NA.   +2 more
europepmc   +3 more sources

Novel roles of DNA glycosylases in neurodegenerative diseases and aging [PDF]

Neural Regeneration Research
Vinod Tiwari, Fivos Borbolis, Deborah L. Croteau, Konstantinos Palikaras, Vilhelm A. Bohr   +4 more
doaj   +2 more sources

Displacement of Slow-Turnover DNA Glycosylases by Molecular Traffic on DNA. [PDF]

Genes (Basel), 2020
Yudkina AV, Endutkin AV, Diatlova EA, Moor NA, Vokhtantsev IP, Grin IR, Zharkov DO.   +6 more
europepmc   +3 more sources

Conformational Dynamics of Biopolymers in the Course of Their Interaction: Multifaceted Approaches to the Analysis by the Stopped-Flow Technique with Fluorescence Detection

Photonics, 2023
This review deals with modern approaches to systematic research on molecular-kinetic mechanisms of damage recognition and removal by pro- and eukaryotic enzymes of DNA base excision repair.
Nikita A. Kuznetsov
doaj   +1 more source