Results 231 to 240 of about 2,102,008 (248)
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Telomere protein arrays stall DNA loop extrusion by condensin

2023
Abstract DNA loop extrusion by SMC proteins is a key process underlying chromosomal organization. It is unknown how loop extruders interact with telomeres where chromosome ends are covered with a dense array of tens of neighboring DNA-binding proteins.
Brian T. Analikwu   +16 more
openaire   +1 more source

Replisomes restrict SMC-mediated DNA-loop extrusion in vivo

Abstract Structural maintenance of chromosomes (SMC) complexes organize genomes by extruding DNA loops, while replisomes duplicate entire chromosomes. These essential molecular machines must collide frequently in every cell cycle, yet how such collisions are resolved in vivo remains
Qin Liao   +3 more
openaire   +2 more sources

Weaving the loops of life: DNA loading by loop-extrusion machines in plasmid defense and genome organization

Molecular Cell
Structural maintenance of chromosome (SMC) complexes organize and segregate DNA via loop extrusion, but the mechanism of the initial DNA loading was unclear. In this issue of Molecular Cell, Roisné-Hamelin et al.1 reported the structures of Wadjet, a specialized plasmid defense system, revealing the ATP-driven conformational cycles enabling DNA capture.
openaire   +2 more sources

Genome folding through loop extrusion by SMC complexes

Nature Reviews Molecular Cell Biology, 2021
Jan-Michaél Peters, Iain Davidson
exaly  

Cohesin mediates DNA loop extrusion and sister chromatid cohesion by distinct mechanisms

Molecular Cell, 2023
Kota Nagasaka   +2 more
exaly  

Faculty Opinions recommendation of DNA loop extrusion by human cohesin.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2020
Giacomo Cavalli, Ivana Jerkovic
  +4 more sources

How DNA loop extrusion mediated by cohesin enables V(D)J recombination

Current Opinion in Cell Biology, 2021
Jan-Michaél Peters
exaly  

High-speed AFM imaging reveals DNA capture and loop extrusion dynamics by cohesin-NIPBL

Journal of Biological Chemistry, 2023
Hongtao Yu, Ilya J Finkelstein, Xu Qi
exaly  

Condensin-driven loop extrusion on supercoiled DNA

Nature Structural and Molecular Biology, 2022
Cees Dekker   +2 more
exaly  

BPS2025 - The effect of trinucleotide extrusions on DNA looping

Biophysical Journal
Jackson Anderson   +2 more
openaire   +1 more source

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