Results 241 to 250 of about 2,686,549 (398)

Single‐Cell Analysis Reveals that Vitamin C Inhibits Bone Metastasis of Renal Cancer via Cell Cycle Arrest and Microenvironment Remodeling

open access: yesAdvanced Science, EarlyView.
3D‐cultured renal cancer cells exhibit stem‐like phenotypes and are more efficient in generating bone metastases. Vitamin C treatment can suppress the development of bone metastasis. Single‐cell transcriptomic analysis reveals that vitamin C inhibits metastasis by inducing tumor cell cycle arrest, suppressing osteoclast differentiation, and reducing ...
Jianye Zhang   +17 more
wiley   +1 more source

LARS2 DNA methylation predicts the prognosis in colon cancer. [PDF]

open access: yesSci Rep
Fu Y, Xie W, Ren Q, Wu J, Long Y, Liu Y.
europepmc   +1 more source

Effects of 5-azacytidine on methylation and expression of specific DNA sequences in C3H 10T1/2 cells.

open access: green, 1984
W.L. Wendy Hsiao   +3 more
openalex   +1 more source

DNA-methylation

open access: yesRadiopaedia.org, 2022
Frank Gaillard
semanticscholar   +1 more source

Targeting GPX4 to Induce Ferroptosis Overcomes Chemoresistance Mediated by the PAX8‐AS1/GPX4 Axis in Intrahepatic Cholangiocarcinoma

open access: yesAdvanced Science, EarlyView.
PAX8‐AS1 drives chemoresistance in intrahepatic cholangiocarcinoma by activating NRF2‐mediated GPX4 transcription and stabilizing GPX4 mRNA via IGF2BP3. Targeting the PAX8‐AS1/GPX4 axis with a GPX4 inhibitor enhances the efficacy of gemcitabine and cisplatin in preclinical models, offering a promising strategy to overcome chemotherapy resistance in ...
Zhi‐Wen Chen   +13 more
wiley   +1 more source

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