Targeting Epigenetic Processes in Glioblastoma Mulitforme [PDF]
, 2007 Among tumors of the central nervous system, gliomas are the most prevalent and are associated with the poorest prognosis. Overall survival rates are low, and combined radioand chemo-therapy provides only marginal benefit; thus it is essential to ...
Earl, Christian
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A type IV modification-dependent restriction enzyme SauUSI from Staphylococcus aureus subsp. aureus USA300 [PDF]
, 2017 A gene encoding a putative DNA helicase from Staphylococcus aureus USA300 was cloned and expressed in Escherichia coli. The protein was purified to over 90% purity by chromatography.
Chan, Siu-Hong +4 more
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Histone methylation marks play important roles in predicting the methylation status of CpG islands [PDF]
, 2008 The methylation status of CpG islands is highly correlated with gene expression. Current methods for computational prediction of DNA methylation only utilize DNA sequence features.
Fan, S., Zhang, M. Q., Zhang, X.
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The Journal of biological chemistry, 1989 Based on the previous findings that the FokI methylase (MFokI) consists of 647 amino acid residues and contains two copies of the segment specific for adenine methylase, Asp-Pro-Pro-Tyr, at amino acid positions 218-221 and 548-551, the role of these copies in the methylation reaction was investigated by introduction of a mutation into each segment. The
H, Sugisaki, K, Kita, M, Takanami
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Balancing noise and plasticity in eukaryotic gene expression [PDF]
, 2012 Coupling the control of expression stochasticity (noise) to the ability of expression change (plasticity) can alter gene function and influence adaptation.
Bajić, Djordje, Poyatos, Juan F.
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Balancing noise and plasticity in gene expression [PDF]
, 2011 Coupling the control of expression stochasticity (noise) with the capacity to expression change (plasticity) can constrain gene function and limit adaptation. Which factors contribute then to modulate this coupling?
Djordje Bajic, Juan F. Poyatos
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Restriction and modification in Bacillus subtilis: gene coding for a BsuR-specific modification methyltransferase in the temperate bacteriophage Φ3T [PDF]
, 1981 The resistance of Phi3T DNA to degradation by the restriction enzyme BsuR or its isoschizomer HaeIII is due to obligatory modification of such DNA. Biochemical and genetical experiments indicate that Phi3T codes for a methyltransferase, which methylates ...
Noyer-Weidner, M. +4 more
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Use and Misuse of Antimicrobial Drugs in Poultry and Livestock: Mechanisms of Antimicrobial Resistance [PDF]
, 2013 Food safety begins on the farm with management practices that contribute to an abundant, safe, and affordable food supply. To attain this goal antimicrobials have been used in all stages of food animal production in the United States and elsewhere around
Toni Poole* and Cynthia Sheffield
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DNA Synthesis, Methylation and Degradation During Conjugation in \u3cem\u3eTetrahymena thermophila\u3c/em\u3e [PDF]
, 1985 We have investigated the timing of DNA synthesis, methylation and degradation during macronuclear development in the ciliate, Tetrahymena thermophila. DNA synthesis was first detected in the anlagen early in macronuclear development, but the majority of ...
Harrison, Gail Singer +1 more
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Mining for Restriction Endonucleases in Nicaragua [PDF]
, 2012 The Molecular Biology Center at the University of Central America in Nicaragua (CBM-UCA) was founded in 1999 to strengthen biotechnology research capacity and education in Nicaragua and the Central American region.
Espinoza-Miranda, Suyén S. +2 more
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