Supervariate Gel Transforms into Various Biominerals in Salt Solutions
Advanced Functional Materials, EarlyView.It is revealed that common calcium‐based biominerals can form from a stable, non‐toxic ‘supervariate’ gel. This tunable gel selectively yields calcite or hydroxyapatite in carbonate/phosphate solutions, while CaCl₂ facilitates the formation of dihydrate calcium pyrophosphate, which converts to hydroxyapatite upon drying. These findings provide insights
Xinxue Tang +12 more
wiley +1 more source
Development of a CRISPR-based cytosine base editor for restriction-modification system inactivation to enhance transformation efficiency in Vibrio Sp. dhg. [PDF]
J Biol EngShon YJ +5 more
europepmc +1 more source
Advanced Functional Materials, EarlyView.Zr‐Fe MOF@Ribociclib@Herceptin (ZFRH) efficiently targets/kills Human Epidermal Growth Factor Receptor 2/Estrogen Receptor‐positive (HER2/ER+) breast cancer cells. It combats tumors by: 1) Elevating ROS, altering redox balance; 2) Inhibiting transcription; 3) Inducing pyroptosis.
Hongkun Miao +8 more
wiley +1 more source
DNA cleavage and methylation specificity of the single polypeptide restriction–modification enzyme LlaGI [PDF]
, 2009 Rachel M. Smith +4 more
openalex +1 more source
Advanced Healthcare Materials, EarlyView.Deinococcus radiodurans‐derived extracellular vesicles (R1‐EVs) provide radioprotection against total‐body irradiation‐induced acute radiation syndrome in mice. R1‐EVs mitigate oxidative damage by scavenging free radicals, promoting intestinal repair, enhancing hematopoietic function, and modulating immune responses. This study highlights the potential
Jeong Moo Han +7 more
wiley +1 more source
Assembly of ascovirus HvAV-3h long DNA fragment using the Transformation-Associated Recombination (TAR) approach in yeast cells. [PDF]
BMC BiotechnolZaghloul HAH, Xiao Z, Hu H, Huang GH.
europepmc +1 more source
Lipid Nanoparticle‐Mediated CRISPR‐Cas13a Delivery for the Control of Bacterial Infection
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.New formulations of lipid nanoparticles (LNPs) that can deliver nucleic acids to Gram‐negative bacteria are proposed to combat bacterial infection. The delivery of nucleic acids by LNPs is aided by LNP‐helpers which weaken the bacterial outer membrane. LNPs encapsulating the Cas13a/gRNA expression vector achieve an antibacterial effect in both in vivo ...
Bookun Kim +9 more
wiley +1 more source
Caloric Restriction and Sirtuins as New Players to Reshape Male Fertility. [PDF]
MetabolitesAndré DCA +3 more
europepmc +1 more source
Crystallization and preliminary crystallographic analysis of the type IIL restriction enzymeMmeI in complex with DNA [PDF]
, 2011 Scott J. Callahan +6 more
openalex +1 more source