Results 231 to 240 of about 405,469 (354)

CRISPR/Cas9‐Assisted Microrobots for Fast and Ultrasensitive “On‐The‐Fly” Next‐Generation DNA Detection

Advanced Functional Materials, EarlyView.
This work presents self‐propelled CRISPR/Cas9‐functionalized Au–MRs for rapid, amplification‐free, “on‐the‐fly” DNA detection. By harnessing motion‐assisted signal recovery, the platform achieved the limit of detection in low fM DNA concentrations, enabling detection across a wide dynamic range within only 5 min, which is significantly faster than any ...
Jyoti, Petr Michálek, Zbyněk Heger, Martin Pumera   +3 more
wiley   +1 more source

Plasmid2MC: efficient cell-free generation of high-purity minicircle DNA for genome editing in mammalian cells. [PDF]

Commun Biol
Oliynyk RT, Mahas A, Karpinski E, Church GM.   +3 more
europepmc   +1 more source

Structure and restriction enzyme maps of the circularly permuted DNA of staphylococcal bacteriophage phi 11 [PDF]

, 1981
Sven Löfdahl, Jan Zabielski, Lennart Philipson   +2 more
openalex   +1 more source

Biomimetic Iridescent Skin: Robust Prototissues Spontaneously Assembled from Photonic Protocells

Advanced Functional Materials, EarlyView.
Uniform nanoparticles are induced to form arrays (photonic crystals) in the cores of biopolymer capsules, endowing these ‘protocells’ with structural color. These protocells are then assembled into large self‐standing objects, i.e., prototissues, with robust mechanical properties as well as iridescent optical properties.
Medha Rath, Briahnah Streeter, Satyam Srivastava, Jemma Wood, William E. Bentley, Taylor J. Woehl, Srinivasa R. Raghavan   +6 more
wiley   +1 more source

Epigenome analysis of an algae-infecting giant virus reveals a unique methylation motif catalogue. [PDF]

PLoS One
Truchon AR, Zinser ER, Wilhelm SW.
europepmc   +1 more source

Microporous Microgel Assemblies Facilitating the Recruitment and Osteogenic Differentiation of Progenitor Cells for Bone Regeneration

Advanced Functional Materials, EarlyView.
There is a significant need for biomaterials with well‐defined stability and bioactivity to support tissue regeneration. In this study, we developed a tunable microgel platform that enables the decoupling of stiffness from porosity, thereby promoting bone regeneration.
Silvia Pravato, Haishuo Guan, Bianca M. Carrara, Mira Jacobs, Matteo Monticelli, Lukas Moser, Thomas Moragues, Andrew J. deMello, Tomaso Zambelli, Martin Ehrbar   +9 more
wiley   +1 more source

Adenylate kinase gene polymerase chain reaction-restriction fragment length polymorphism to differentiate Escherichia coli, Escherichia fergusonii, and Citrobacter freundii: a molecular diagnostic study. [PDF]

J Yeungnam Med Sci
Dahal RH, Choi YJ, Kim B, Rana MS, Shin JH, Kim J, Kim S.   +6 more
europepmc   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Modification of Deoxyribonucleic Acid with Indole-Linked Nucleotides Induces BZ- and Z‑Conformation and Alters Its Sensitivity to Enzymatic Cleavage. [PDF]

ACS Omega
Lingala S, Fisiuk A, Stephen M, Mohanrao R, Klingsberg J, Vecchioni S, Volvovitz ES, Rozhkov S, Mallikaratchy P.   +8 more
europepmc   +1 more source

A 3D Biofabricated Disease Model Mimicking the Brain Extracellular Matrix Suitable to Characterize Intrinsic Neuronal Network Alterations in the Presence of a Breast Tumor Disseminated to the Brain

Advanced Functional Materials, EarlyView.
A 3D disease model is developed using customized hyaluronic‐acid‐based hydrogels supplemented with extracellular matrix (ECM) proteins resembling brain ECM properties. Neurons, astrocytes, and tumor cells are used to mimic the native brain surrounding.
Esra Türker, Mateo S. Andrade Mier, Jessica Faber, Mike Friedrich, Zan Lamberger, Jeannette Weigelt, Christian Stigloher, Nicoletta Murenu, Natascha Schaefer, Jörg Tessmar, Gregor Lang, Silvia Budday, Katrin G. Heinze, Antje Appelt‐Menzel, Pamela L. Strissel, Reiner Strick, Carmen Villmann   +16 more
wiley   +1 more source