{BiQ} Analyzer {HiMod}: An Interactive Software Tool for High-throughput Locus-specific Analysis of 5-Methylcytosine and its Oxidized Derivatives [PDF]
Recent data suggest important biological roles for oxidative modifications of methylated cytosines, specifically hydroxymethylation, formylation and carboxylation. Several assays are now available for profiling these DNA modifications genome-wide as well
Becker, D. +5 more
core +2 more sources
Structural analysis of DNA binding by C.Csp231I, a member of a novel class of R-M controller proteins regulating gene expression [PDF]
In a wide variety of bacterial restriction–modification systems, a regulatory `controller' protein (or C-protein) is required for effective transcription of its own gene and for transcription of the endonuclease gene found on the same operon.
Kneale, G. G. +5 more
core +2 more sources
DNA sequence analysis of SLC26A5, encoding prestin, in a patient-control cohort: identification of fourteen novel DNA sequence variations. [PDF]
Prestin, encoded by the gene SLC26A5, is a transmembrane protein of the cochlear outer hair cell (OHC). Prestin is required for the somatic electromotile activity of OHCs, which is absent in OHCs and causes severe hearing impairment in mice lacking ...
Jacob S Minor +3 more
doaj +1 more source
Wenzi Bi, Licheng Xu, Laibin Zong, Zhiqiang Zhu, Xiaoping Xia The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, Zhejiang, People’s Republic of ChinaCorrespondence: Xiaoping Xia, Tel +86579-89979999, Email xiaopingxia@zju.edu ...
Bi W, Xu L, Zong L, Zhu Z, Xia X
doaj
Molecular characterization and subtyping of Blastocystis in urticarial patients in Turkey
Objective: To investigate Blastocystis’ etiologic role and association with gastrointestinal symptomatology in acute and chronic urticaria patients and to identify Blastocystis subtypes responsible for urticaria.
Merve Aydin +8 more
doaj +1 more source
Copper Ions Induce DNA Sequence Variation in Zygotic Embryo Culture-Derived Barley Regenerants
In vitro tissue culture could be exploited to study cellular mechanisms that induce sequence variation. Altering the metal ion composition of tissue culture medium affects biochemical pathways involved in tissue culture-induced variation. Copper ions are
Renata Orłowska +2 more
doaj +1 more source
Enhanced Multi-Criteria DNA Sequence Analysis Using Neutrosophic Logic and Deep Learning: An Integrated Approach for Comparison and Classification [PDF]
This paper presents a comprehensive approach for analyzing DNA sequences and attempts to find a practical solution to the problems of comparing and classifying genomic data, which have become increasingly complex and noisy.
Romany M. Farag +6 more
doaj +1 more source
A Deep Learning Model for Predicting DNA N6-Methyladenine (6mA) Sites in Eukaryotes
DNA N6-methyladenine (6mA) is an epigenetic modification, which is involved in many biological regulation processes like DNA replication, DNA repair, transcription, and gene expression regulation.
Lokuthota Hewage Roland +1 more
doaj +1 more source
Completely mitochondrial genome of Neolissochilus heterostomus
In this study, we determined the complete mitochondrial genome of Neolissochilus heterostomus. The genome is 16,585 bp in length, including 2 ribosomal RNA genes, 13 proteins-coding genes, 22 transfer RNA genes, and two non-coding control regions ...
Jinghong He +5 more
doaj +1 more source
High-Throughput DNA Analysis Platform Based on an Optofluidic Ring Resonator Laser
We demonstrate an optofluidic laser using DNA microdroplets, an intercalating dye, and a glass capillary ring resonator. Only the target DNA emits the laser signal, while the non-target DNA, including those with single-base mismatches, exhibits zero ...
Chan Seok Jun, Wonsuk Lee
doaj +1 more source

