Results 21 to 30 of about 3,718,372 (390)
Investigations into the molecular effects of single nucleotide polymorphism [PDF]
Objectives: DNA sequences are very rich in short repeats and their pattern can be altered by point mutations. We wanted to investigate the effect of single nucleotide polymorphism (SNP) on the pattern of short DNA repeats and its biological consequences.
Lohrer, Horst D., Tangen, Uwe
core +1 more source
{BiQ} Analyzer {HiMod}: An Interactive Software Tool for High-throughput Locus-specific Analysis of 5-Methylcytosine and its Oxidized Derivatives [PDF]
Recent data suggest important biological roles for oxidative modifications of methylated cytosines, specifically hydroxymethylation, formylation and carboxylation. Several assays are now available for profiling these DNA modifications genome-wide as well
Becker, D.+5 more
core +2 more sources
BEAST: Bayesian evolutionary analysis by sampling trees [PDF]
Background The evolutionary analysis of molecular sequence variation is a statistical enterprise. This is reflected in the increased use of probabilistic models for phylogenetic inference, multiple sequence alignment, and molecular population genetics ...
Drummond, Alexei J., Rambaut, Andrew
core +3 more sources
As the distribution of Candida species and their susceptibility to antifungal agents have changed, a new means of accurately and rapidly identifying these species is necessary for the successful early resolution of infection and the subsequent reduction ...
Constanza Giselle Taverna+6 more
doaj +1 more source
Analysis of DNA sequence variation within marine species using Beta-coalescents [PDF]
We apply recently developed inference methods based on general coalescent processes to DNA sequence data obtained from various marine species. Several of these species are believed to exhibit so-called shallow gene genealogies, potentially due to extreme
Birkner, Matthias+2 more
core +3 more sources
Sequencing and Analysis of Neanderthal Genomic DNA [PDF]
Our knowledge of Neanderthals is based on a limited number of remains and artifacts from which we must make inferences about their biology, behavior, and relationship to ourselves. Here, we describe the characterization of these extinct hominids from a new perspective, based on the development of a Neanderthal metagenomic library and its ...
Jonathan K. Pritchard+12 more
openaire +5 more sources
Comparative Viral Metagenomics of Environmental Samples from Korea [PDF]
The introduction of metagenomics into the field of virology has facilitated the exploration of viral communities in various natural habitats. Understanding the viral ecology of a variety of sample types throughout the biosphere is important per se, but ...
Min-Soo Kim, Tae Woong Whon, Jin-Woo Bae
doaj +1 more source
Molecular characterization and subtyping of Blastocystis in urticarial patients in Turkey
Objective: To investigate Blastocystis’ etiologic role and association with gastrointestinal symptomatology in acute and chronic urticaria patients and to identify Blastocystis subtypes responsible for urticaria.
Merve Aydin+8 more
doaj +1 more source
Wenzi Bi, Licheng Xu, Laibin Zong, Zhiqiang Zhu, Xiaoping Xia The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, Zhejiang, People’s Republic of ChinaCorrespondence: Xiaoping Xia, Tel +86579-89979999, Email xiaopingxia@zju.edu ...
Bi W, Xu L, Zong L, Zhu Z, Xia X
doaj
From Nonspecific DNA–Protein Encounter Complexes to the Prediction of DNA–Protein Interactions [PDF]
©2009 Gao, Skolnick. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
A Sarai+49 more
core +4 more sources