Results 241 to 250 of about 37,201 (270)

Heterochiral DNA Strand-Displacement Circuits

Journal of the American Chemical Society, 2017
The absence of a straightforward strategy to interface native d-DNA with its enantiomer l-DNA-oligonucleotides of opposite chirality are incapable of forming contiguous Watson-Crick base pairs with each other-has enforced a "homochiral" paradigm over the field of dynamic DNA nanotechnology.
Adam M. Kabza, Brian E. Young, Jonathan T. Sczepanski   +2 more
openaire   +2 more sources

Performing DNA Strand Displacement with DNA Polymerase

2020
Significant improvements to the dynamic DNA nano science have emerged in recent years, primarily due to the elaborate design of toehold-mediated DNA strand displacement (TMSD). However, it remains an ongoing challenge to design huge-scaled TMSD based sophisticated dynamic DNA structures without base-pair mismatching or unwanted secondary structures ...
Zhiyu Wang, Yingxin Hu, Zhekun Chen, Sulin Liao, Yabing Huang   +4 more
openaire   +1 more source

Analog Computation by DNA Strand Displacement Circuits

ACS Synthetic Biology, 2016
DNA circuits have been widely used to develop biological computing devices because of their high programmability and versatility. Here, we propose an architecture for the systematic construction of DNA circuits for analog computation based on DNA strand displacement.
Tianqi, Song, Sudhanshu, Garg, Reem, Mokhtar, Hieu, Bui, John, Reif   +4 more
openaire   +2 more sources

Circular DNA Logic Gates with Strand Displacement

Langmuir, 2009
Circular DNA logic gates were constructed on the basis of DNA three-way branch migration. In this logic system, circular DNA was used as a basic work unit and linear single-strand DNA was used as input and output signals. Making use of the circular structure, most of the DNA-specific recognition regions were designed in a single DNA ring.
Cheng, Zhang, Jing, Yang, Jin, Xu
openaire   +2 more sources

Connecting localized DNA strand displacement reactions

Nanoscale, 2015
Design and characterization of a DNA-based localized amplification circuit which, upon tethering on a DNA origami platform, greatly accelerates the catalytic response.
Ismael Mullor, Ruiz, Jean-Michel, Arbona, Amitkumar, Lad, Oscar, Mendoza, Jean-Pierre, Aimé, Juan, Elezgaray   +5 more
openaire   +2 more sources

Autonomous Resolution Based on DNA Strand Displacement

2011
We present a computing model based on the technique of DNA strand displacement which performs a chain of logical resolutions with logical formulae in conjunctive normal form. The model is enzymefree and autonomous. Each clause of a formula is encoded in a separate DNA molecule: propositions are encoded assigning a strand to each proposition p, and its ...
Alfonso Rodríguez-Patón, Iñaki Sainz de Murieta, Petr Sosík   +2 more
openaire   +1 more source

Mechanism of DNA multimerization caused by strand-displacement DNA polymerases

Analytical Biochemistry
It has been recently shown that for Bst DNA polymerase, the side isothermal amplification reaction named multimerization (MM) proceeds under certain conditions. MM hinders interpretation of amplification results and reduces the accuracy and reliability of DNA/RNA diagnostics.
Assol R. Sakhabutdinova, Ravil R. Garafutdinov   +1 more
openaire   +2 more sources

DNA strand displacement system running logic programs

Biosystems, 2014
The paper presents a DNA-based computing model which is enzyme-free and autonomous, not requiring a human intervention during the computation. The model is able to perform iterated resolution steps with logical formulae in conjunctive normal form. The implementation is based on the technique of DNA strand displacement, with each clause encoded in a ...
Alfonso Rodríguez-Patón, Iñaki Sainz de Murieta, Petr Sosík   +2 more
openaire   +2 more sources

Dynamic DNA nanotechnology using strand-displacement reactions

Nature Chemistry, 2011
The specificity and predictability of Watson-Crick base pairing make DNA a powerful and versatile material for engineering at the nanoscale. This has enabled the construction of a diverse and rapidly growing set of DNA nanostructures and nanodevices through the programmed hybridization of complementary strands.
David Yu, Zhang, Georg, Seelig
openaire   +2 more sources

Base Conversion Model Based on DNA Strand Displacement

2020
DNA computing has the advantages of high parallelism and large storage. In this paper, DNA strand displacement techniques are applied to binary to decimal system. In the field of DNA calculation, binary numerical calculation is relatively mature, but it is difficult to implement decimal calculation.
Zhao Chen, Zhixiang Yin, Jianzhong Cui, Zhen Tang, Qiang Zhang 0008   +4 more
openaire   +1 more source