Results 201 to 210 of about 57,780 (287)

Conformations of the three gates in Saccharomyces cerevisiae topoisomerase II and their response to DNA, nucleotide, and etoposide. [PDF]

J Biol Chem
Stelljes JT, Klostermeier D.
europepmc   +1 more source

Structural interactions of BWC0977 with Klebsiella pneumoniae topoisomerase IV and biochemical basis of its broad-spectrum activity. [PDF]

Commun Biol
Nandishaiah R, Murakami S, Hameed P S, Aoki M, Okada U, Yamashita E, Venkatesan S, Bharatham N, Sarma S, Shanbhag AP, Sharma S, Rao R, Ramachandran V, Balasubramanian V, Datta S, Katagihallimath N.   +15 more
europepmc   +1 more source

Type IA DNA topoisomerases: Strictly one step at a time

Proceedings of the National Academy of Sciences of the United States of America, 2002
J. Champoux
semanticscholar   +1 more source

Type II DNA Topoisomerases Cause Spontaneous Double-Strand Breaks in Genomic DNA

Type II DNA Topoisomerases Cause Spontaneous Double-Strand Breaks in Genomic DNA
Type II DNA topoisomerase enzymes (TOP2) catalyze topological changes by strand passage reactions. They involve passing one intact double stranded DNA duplex through a transient enzyme-bridged break in another (gated helix) followed by ligation of the break by TOP2.
openaire  

Topoisomerase inhibitory activity of ethanolic extracts from botanicals <i>Coptis chinensis</i> and <i>Salvia officinalis</i>. [PDF]

J Med Microbiol
Ingersoll W, Trapp S, Turner T, Ruiz G, Langland J.   +4 more
europepmc   +1 more source

Molecular resistance mechanisms to newly approved antibiotics (2017-2025) in WHO priority pathogens. [PDF]

Front Microbiol
Sartori M, Toppo S, Lavezzo E.
europepmc   +1 more source

New Insights into the Geometry and Topology of DNA Replication Intermediates. [PDF]

Biology (Basel)
Martínez V, Ruiz-Díaz E, Cardozo D, Cappo C, Schaerer CE, Cebrián J, Krimer DB, Fernández-Nestosa MJ.   +7 more
europepmc   +1 more source

Substrate binding of human and bacterial type IA topoisomerase: An experimentation with AlphaFold 3.0. [PDF]

Comput Struct Biotechnol J
Mamun Y, Aguado A, Preza A, Kadel A, Mogallur A, Gonzalez B, De La Rosa J, Diaz D, Evdokimova P, Karki U, Tse-Dinh YC, Chapagain P.   +11 more
europepmc   +1 more source

Scaffold Simplification Yields Potent Antibacterial Agents That Target Bacterial Topoisomerases. [PDF]

Molecules
Khudiakova L, Komarova K, Zhuravlev M, Deniskin D, Golovanov A, Nichugovskiy A, Babkin K, Zakharova M, Chudinov M, Rogacheva E, Kraeva L, Shevtsova O, Ipatova D, Skvortsov D, Lukianov D, Kryakvin M, Gureev M, Lukin A.   +17 more
europepmc   +1 more source

DNA TOP1α coordinates anther morphogenesis and fertility through gene regulatory networks in arabidopsis. [PDF]

Sci Rep
Elesawi IE, Zhang N, Hashem AM, Yao L, Abdullah HM, Maher M, Alshaya DS, Al Aboud NM, ALshamrani SM, Shehata WF, Hassanin AA, El-Moneim DA, Chen C.   +12 more
europepmc   +1 more source