Results 171 to 180 of about 28,674 (272)

Regulation of R‐Loop Dynamics by Proteins and Long Noncoding RNAs: An Emerging Paradigm for Cancer Treatment

Cancer Science, Volume 117, Issue 2, Page 297-307, February 2026.
R‐loops are three‐stranded nucleic acid structures whose dysregulation leads to genomic instability and cancer progression. This review summarizes the protein and lncRNA machineries that regulate R‐loop dynamics and discusses the therapeutic potential of targeting these pathways in cancer.
Miho M. Suzuki, Keiko Shinjo, Tatsunori Nishimura, Yutaka Kondo   +3 more
wiley   +1 more source

Cellular DNA Topoisomerases Are Required for the Synthesis of Hepatitis B Virus Covalently Closed Circular DNA. [PDF]

J Virol, 2019
Sheraz M, Cheng J, Tang L, Chang J, Guo JT.   +4 more
europepmc   +1 more source

Recombination mediated by vaccinia virus DNA topoisomerase I in Escherichia coli is sequence specific.

, 1991
Stewart Shuman
openalex   +2 more sources

Eukaryotic topoisomerases recognize nucleic acid topology by preferentially interacting with DNA crossovers. [PDF]

, 1990
Lynn Zechiedrich, Neil Osheroff
openalex   +1 more source

Topoisomerase IV tracks behind the replication fork and the SeqA complex during DNA replication in Escherichia coli [PDF]

, 2021
Emily Helgesen, Frank Sætre, Kirsten Skarstad   +2 more
openalex   +1 more source

Global diversification of coastal Cafius rove beetles (Coleoptera: Staphylinidae) driven by ocean currents since the early Miocene

Cladistics, Volume 42, Issue 1, Page 79-94, February 2026.
Abstract As our understanding of abiotic factors continues to grow, along with insights into the biological traits of organisms, so too does the sophistication of studies exploring global diversification and spatio‐temporal distribution patterns. The global distribution of coastal Cafius rove beetles, combined with the endemic distribution patterns ...
Kee‐Jeong Ahn, Jeong‐Hun Song
wiley   +1 more source

Figure S3 from A Novel Dual ATM/DNA-PK Inhibitor, XRD-0394, Potently Radiosensitizes and Potentiates PARP and Topoisomerase I Inhibitors [PDF]

Tona M. Gilmer, Chun-Hsiang Lai, Kexiao Guo, Katherine Deland, Kathleen A. Ashcraft, Amy E. Stewart, Yaode Wang, Jianmin Fu, Kris C. Wood, David G. Kirsch, Michael B. Kastan   +10 more
openalex   +1 more source

Clinical Characteristics, Molecular Diagnosis, and Drug Resistance Profiles of Nontuberculous Mycobacteria Infections: A Retrospective Analysis Using PCR Melting Curve Technology

Clinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT Nontuberculous mycobacteria (NTM) are emerging global pathogens. This study aimed to analyze the clinical features, species distribution, and drug resistance profiles of NTM infections in a northern Chinese hospital. A retrospective cohort study included 1769 patients with suspected mycobacterial infection from August 2023 to July 2025.
Kedi Wang, Dongjiang Xu, Yan Gao, Wen Zhao, Kaihui Ma   +4 more
wiley   +1 more source

A consensus sequence for cleavage by vertebrate DNA topoisomerase II

, 1988
Jeffrey R. Spitzner, Mark T. Muller
openalex   +2 more sources

An interbacterial cysteine protease toxin inhibits cell growth by targeting type II DNA topoisomerases GyrB and ParE. [PDF]

PLoS Biol
Song PY, Tsai CE, Chen YC, Huang YW, Chen PP, Wang TH, Hu CY, Chen PY, Ku C, Hsia KC, Ting SY.   +10 more
europepmc   +1 more source