Results 181 to 190 of about 14,206 (239)

Minimal mutational requirements for conversion of a telomere resolvase into a Cre-like site-specific recombinase. [PDF]

PLoS One
Huang SH, Kobryn K.
europepmc   +1 more source

Cladosporium cladosporioides, endophyte of Strelitzia nicolai, as a new producer of Alternariol monomethyl ether with a potential cytotoxic activity. [PDF]

Sci Rep
Farag NM, El-Sayed ASA, Fikry E, Tawfeek N, El-Shafae AM, El-Domiaty MM.   +5 more
europepmc   +1 more source

Kinetoplast-Directed Therapies: A Selective Mitochondrial Approach to Combat Leishmaniasis. [PDF]

Pharmaceuticals (Basel)
Botero-Buitrago JA, Cardozo-Muñoz JC, Cisneros D, Santamaría-Aguirre J, Torres K, Espuelas S, Carrión J, Dardonville C.   +7 more
europepmc   +1 more source

TOP1 and TOP2 complementarily maintain DNA replication fork progression in vertebrates. [PDF]

J Biol Chem
Umemura K, Ooka M, Sojo M, Seki M, Xia M, Hirota K, Abe T.   +6 more
europepmc   +1 more source

Origin and evolution of DNA topoisomerases

Biochimie, 2007
The DNA topoisomerases are essential for DNA replication, transcription, recombination, as well as for chromosome compaction and segregation. They may have appeared early during the formation of the modern DNA world. Several families and subfamilies of the two types of DNA topoisomerases (I and II) have been described in the three cellular domains of ...
Simonetta Gribaldo, Daniele Gadelle, Marie-Claude Serre   +2 more
exaly   +6 more sources

Type I DNA Topoisomerases

Journal of Medicinal Chemistry, 2017
DNA topoisomerases constitute a large family of enzymes that are essential for all domains of life. Although they share general reaction chemistry and the capacity to govern DNA topology and resolve strand entanglements during fundamental molecular processes, they are characterized by differences in their structural organization, modes of enzymatic ...
CAPRANICO, GIOVANNI, MARINELLO, JESSICA, CHILLEMI, GIOVANNI   +2 more
openaire   +6 more sources

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DNA Topoisomerases

EcoSal Plus, 2009
DNA topoisomerases are enzymes that control the topological state of DNA in all cells; they have central roles in DNA replication and transcription. They are classified into two types, I and II, depending on whether they catalyze reactions involving the breakage of one or both strands of DNA.
Katherine, Evans-Roberts, Anthony, Maxwell   +1 more
openaire   +3 more sources

Alignment and phylogenetic analysis of type II DNA topoisomerases [PDF]

Journal of Biosciences, 1996
DNA topoisomerases have been evolved to solve the topological problems of DNA during replication, transcription, recombination and segregation. Discovery of several new enzymes and their characterization has necessitated this compilation.
Valakunja Nagaraja, Nagaraja V
exaly   +3 more sources