Results 11 to 20 of about 2,856,528 (208)

Manganese-based nanoadjuvants for enhancement of immune effect of DNA vaccines [PDF]

Frontiers in Bioengineering and Biotechnology, 2022
As a highly pathogenic avian influenza virus, influenza A (H5N1) has been reported to infect humans, posing a major threat to both poultry industry and public health. It is an urgent need to develop a kind of effective vaccine to prevent death and reduce
Qiang Ma, Qiang Ma, Yongxu Mu, Lidong Gong, Chuanda Zhu, Shiming Di, Ming Cheng, Jinming Gao, Jihai Shi, Liang Zhang   +9 more
doaj   +2 more sources

The next-generation DNA vaccine platforms and delivery systems: advances, challenges and prospects

Frontiers in Immunology
Vaccines have proven effective in the treatment and prevention of numerous diseases. However, traditional attenuated and inactivated vaccines suffer from certain drawbacks such as complex preparation, limited efficacy, potential risks and others.
Bowen Lu, Bowen Lu, Bowen Lu, Jing Ming Lim, Boyue Yu, Siyuan Song, Praveen Neeli, Navid Sobhani, Pavithra K, Srinivasa Reddy Bonam, Rajendra Kurapati, Junnian Zheng, Junnian Zheng, Dafei Chai, Dafei Chai, Dafei Chai   +15 more
doaj   +2 more sources

Accounting Problems Under the Excess Profits Tax [PDF]

, 1943
DNA vaccines based on subunits from pathogens have several advantages over other vaccine strategies. DNA vaccines can easily be modified, they show good safety profiles, are stable and inexpensive to produce, and the immune response can be focused to the
A Biragyn, A Biragyn, A Biragyn, A Iwasaki, A Smed-Sorensen, A Viola, AB Fredriksen, AB Fredriksen, Agnete B. Fredriksen, AJ McMichael, AK Roos, B Ferraro, B Peng, Bjarne Bogen, BS Davis, C Cheong, C Coban, C Trumpfheller, D D’Ambrosio, DH Barouch, DP Snider, EB Compeer, EM Borroni, G Carayanniotis, G Grodeland, G Grodeland, G Nchinda, H Kawamura, H Qin, H Takahashi, HC Spang, I Oynebraten, Inger Øynebråten, J Aliberti, JD Altman, JJ Kim, Jorma Hinkula, K Ozato, KA Garver, KE Stephenson, KW Schjetne, L Cohn, L Norderhaug, L Qin, LJ Cruz, M Altfeld, M Charmoy, M Froyland, M Kreutz, M Mack, M Malissen, M Maurer, MA Liu, Mauricio M. Rodrigues, MS Neuberger, NY Sardesai, O Kew, OP Joffre, P Menten, PA Broliden, PA Ruffini, PF McKay, PJ Bergman, PJ Tacken, R Schiavo, R Song, RM Steinman, S Flingai, S Santra, T Schiffner, W Liu, WJ Karpus, WR Heath, Z Xiang   +73 more
core   +24 more sources

DNA Vaccines [PDF]

Critical Reviews™ in Immunology, 1998
DNA vaccination against infectious diseases has created a new field of applied molecular immunology. cDNAs for 'protective' protein epitopes can be inserted into vectors containing strong mammalian promoters for high expression. Here we discuss the mechanisms of DNA vaccination and the successful and sometimes unsuccessful applications of DNA ...
W C, Lai, M, Bennett
  +7 more sources

DNA Vaccines Encoding Antigen Targeted to MHC Class II Induce Influenza-Specific CD8+ T Cell Responses, Enabling Faster Resolution of Influenza Disease [PDF]

, 2016
Current influenza vaccines are effective but imperfect, failing to cover against emerging strains of virus and requiring seasonal administration to protect against new strains. A key step to improving influenza vaccines is to improve our understanding of
Bogen, B, Brunsvik Frediksen, A, Grodeland, G, Kinnear, E, Lambert, L, Lindberg, MM, Mcdonald, JU, Stubsrud, E, Tregoning, JS   +8 more
core   +12 more sources

Brucella abortus RB51 lipopolysaccharide influence as an adjuvant on the therapeutic efficacy of HPV16 L1 and HPV16 E7 DNA vaccines [PDF]

Iranian Journal of Basic Medical Sciences, 2021
Objective(s): Human papillomavirus (HPV) is a primary contributing agent of cervical cancer. Eradication of HPV-related infections requires therapeutic strategies.
Masoumeh Shirmohammadi, Hoorieh Soleimanjahi, Zahra Kianmehr, Hesam Karimi, Sussan Kabudanian Ardestani   +4 more
doaj   +1 more source

A brief review on DNA vaccines in the era of COVID-19

Future Virology, 2021
This article provides a brief overview of DNA vaccines. First, the basic DNA vaccine design strategies are described, then specific issues related to the industrial production of DNA vaccines are discussed, including the production and purification of ...
Maryam Shafaati, M. Saidijam, M. Soleimani, F. Hazrati, Rasoul Mirzaei, Bagher Amirheidari, Hamid Tanzadehpanah, Sajad Karampoor, Sima Kazemi, B. Yavari, Hanie Mahaki, Mohsen Safaei, F. Rahbarizadeh, Pouria Samadi, Yaghoub Ahmadyousefi   +14 more
semanticscholar   +1 more source

DNA vaccines for SARS-CoV-2: toward third-generation vaccination era

Expert Review of Vaccines, 2021
Introduction: Coronavirus outbreak 2019 (COVID-19) has affected all the corners of the globe and created chaos to human life. In order to put some control on the pandemic, vaccines are urgently required that are safe, cost effective, easy to produce, and
Vivek P. Chavda, R. Pandya, V. Apostolopoulos   +2 more
semanticscholar   +1 more source

Human endogenous retrovirus-enveloped baculoviral DNA vaccines against MERS-CoV and SARS-CoV2

npj Vaccines, 2021
Here we report a recombinant baculoviral vector-based DNA vaccine system against Middle East respiratory syndrome coronavirus (MERS-CoV) and the severe acute respiratory syndrome coronavirus-2 (SARS-CoV2).
Hansam Cho, Y. Jang, Kihoon Park, Hanul Choi, A. Nowakowska, H. Lee, Minjee Kim, M. Kang, Jin-Hoi Kim, H. Shin, Y. Oh, Y. Kim   +11 more
semanticscholar   +1 more source

DNA Vaccines

Japanese Journal of Pharmacology, 2000
DNA vaccination or genetic immunization is a rapidly developing technology that offers new approaches for the prevention and therapy of disease. Regarding the inoculation method of DNA vaccine, we recommend the gene gun delivery system, which is a highly reliable method compared to intramuscular inoculation. DNA vaccines could have potential advantages
Y, Koide, T, Nagata, A, Yoshida, M, Uchijima   +3 more
  +8 more sources