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Current Protocols in Human Genetics, 2003 AbstractThis unit details some of the key methods for setting up and testing DNA vaccines in animal models. The basic procedures are discussed, as well as alternative methods that have been developed over the past several years. The gives step‐by‐step instructions for administering the DNA vaccine via intramuscular injection of the quadriceps muscle ...
Jeffrey B, Ulmer, Rino, Rappuoli
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Биопрепараты: Профилактика, диагностика, лечение, 2021 The main triggers of new infectious diseases, including those with pandemic potential, are: spontaneous emergence of infectious strains which are more virulent for humans and contribute to transmission of pathogenic microorganisms, environmental changes,
G. G. Onishchenko +3 more
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Allergy, 1999 Chronic infections with hepatitis B (HBV) and hepatitis C (HCV) virus are worldwide problems often leading to the development of chronic liver disease and hepatocellular carcinoma. Genetic immunizations with DNA encoding for structural and nonstructural proteins of HCV and HBV in experimental mice generate a broad base CD4+ and CD8+ cellular immune ...
H L, Spiegelberg, E, Raz
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Next‐Generation Vaccines: Nanoparticle‐Mediated DNA and mRNA Delivery
Advanced Healthcare Materials, 2021 Nucleic acid vaccines are a method of immunization aiming to elicit immune responses akin to live attenuated vaccines. In this method, DNA or messenger RNA (mRNA) sequences are delivered to the body to generate proteins, which mimic disease antigens to ...
William Ho +5 more
semanticscholar +1 more source
Analysis of Promising Approaches to COVID-19 Vaccine Development
Биопрепараты: Профилактика, диагностика, лечение, 2020 The number of confirmed COVID-19 cases worldwide amounted to 50 million at the beginning of November 2020. This is clearly not enough for the formation of herd immunity, which will prevent repeated outbreaks of the disease.
G. G. Onishchenko +3 more
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Nucleic acid vaccines for human papillomavirus; prevention or treatment [PDF]
Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2019 Introduction: Cervical cancer is the fourth common cancer among women. In almost all cases of this cancer, infection to a high risk human papilloma virus (HPV) especially type 16 and 18 is observed.
Solmaz Moniri Javadhesari +2 more
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New vaccines on the horizon [PDF]
Arhiv za farmaciju, 2019 Vaccines are considered to be one of the greatest public health achievements of the last century. As a result of widespread vaccine use, the smallpox virus has been completely eradicated and the incidence of other diseases such as polio, measles, tetanus
Arsenović-Ranin Nevena
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Immunogenicity studies of nucleic acid-based antirabies vaccines in BALB/c mice: A systematic review
BLDE University Journal of Health Sciences, 2023 Improved vaccine efficacy has a major impact on future rabies prevention and control. In this systematic review, a comparative assessment of different nucleic acid-based antirabies vaccination tools developed using different methods, in different ...
Hasanthi Rathnadiwakara +6 more
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Current Molecular Medicine, 2001 Within the last decade bacterial plasmids encoding foreign antigens have revolutionized vaccine design. Although no DNA vaccine has yet been approved for routine human or veterinary use, the potential of this vaccine modality has been demonstrated in experimental animal models.
Reyes-Sandoval, A, Ertl, H
openaire +4 more sources
DNA vaccines and recombinant allergens with reduced allergenic activity treat allergies
Russian Open Medical Journal, 2021 This review is intended to familiarize readers with major novel directions of developing allergy vaccines, their structure, as well as the mechanisms of forming a new immunological response in the course of the treating immunoglobulin E (IgE)-mediated ...
Stanislava Yu. Petrova +4 more
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