Results 101 to 110 of about 46,100 (245)
Abstract BACKGROUND Obesity and its metabolic complications, such as insulin resistance and cognitive decline, remain a global health challenge. Green tea (Camelia sinensis) and ω‐3 polyunsaturated fatty acids (PUFAs) are recognized for their antioxidant, anti‐inflammatory, and neuroprotective properties.
Paola Finetti‐Casanova +5 more
wiley +1 more source
Levothyroxine Treatment During Pregnancy: A Metabolomics Study
ABSTRACT Levothyroxine is one of the most prescribed drugs during pregnancy. Our aim was to determine levothyroxine treatment‐associated changes in the metabolite profiles and link these to the health of the newborn. Metabolite profiles of 118 levothyroxine‐treated and 118 healthy control pregnancies were determined with nuclear magnetic resonance ...
Olli Kärkkäinen +3 more
wiley +1 more source
Amyloid‐β aggregates induce vasculopathy via ferroptosis in brain endothelial cells
Blood–brain barrier (BBB) disruption is evident in brains with amyloidopathy. In this study, we demonstrate that amyloid β (Aβ) drives abnormal lipid metabolism and lipid droplet formation in brain endothelial cells, leading to lipid peroxidation and ferroptosis.
Suhyeon Son +7 more
wiley +1 more source
Updates on Mediterranean diet and health status: active ingredients and pharmacological mechanisms
The Mediterranean diet (MedDiet) is among the most extensively studied dietary patterns and has been consistently associated with reduced risk of all‐cause mortality, cardiovascular disease, metabolic disorders, cognitive decline and several types of cancers.
Lukas Schwingshackl +3 more
wiley +1 more source
This review reconsiders the amyloid cascade by placing lipid dynamics at its core. It shows that free lipids, governed by critical micellar concentration, act as pathological chaperones that redirect amyloid aggregation toward membrane‐damaging species.
Sofia Serravalle +6 more
wiley +1 more source
Graphical overview of the effects of the high‐fat, high‐sucrose (HFHS) diet regime and 2‐week cannabigerol (CBG) treatment on the intramuscular long‐chain fatty acids (LCFAs) trafficking and lipid metabolism, with subsequent implications for mitochondrial cardiolipin (CL) composition in the red gastrocnemius muscle.
Patrycja Bielawiec +3 more
wiley +1 more source
The Emerging Parkinson's Disease Oxylipin‐Ome
ABSTRACT Parkinson Disease (PD) is increasingly considered a proteinopathy and lipidopathy. This proteinopathy+lipidopathy paradigm has been further refined to a fatty acid (FA)‐opathy, centering dysregulated FA metabolism as fundamental in PD lipid dysfunction.
Julia C. Kelliher, Saranna Fanning
wiley +1 more source
ABSTRACT The aim of this study was to provide an initial description of the embryology and larval development of Balistes capriscus species obtained from natural spawning in captivity. The study also aimed to assess the stocking density and the impact of offering four types of live food as the initial feed during the larviculture phase. Observations of
Henrique David Lavander +9 more
wiley +1 more source
ABSTRACT Lipids are important for metabolic processes, mainly cytokine regulation in the skeletal muscle and liver. Considering the soybean oil concentration, a weighted gene co‐expression network analysis (WGCNA) was used to perform an integrative analysis in skeletal muscle and liver tissues.
Fernanda Nery Ciconello +9 more
wiley +1 more source
Abstract Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder driven by intersecting pathological processes. Persistent attrition in AD drug‐development pipelines highlights the limited clinical impact of single‐target therapies and has increased interest in multi‐target approaches acting on shared biological hubs.
Humberto Martínez‐Orozco +4 more
wiley +1 more source

