Results 151 to 160 of about 96,904 (327)
Stress Nutrition in Aquatic Animals: From Definition to Practice
Reviews in Aquaculture, Volume 18, Issue 1, January 2026.ABSTRACT Aquaculture faces numerous challenges, with stress being one of the major issues that lead to growth loss, metabolic disorders, weakened immunity, redox imbalance, and organ damage in aquatic animals. Nutritional intervention is one of the effective strategies to address these problems. Traditional research has primarily focused on the impacts
Jian Zhang +8 more
wiley +1 more source
The FASEB Journal, Volume 39, Issue 23, 15 December 2025.Resolvin D2 is a specialized pro‐resolving mediator transducing atheroprotective effects on myeloid cells through the GPR18 receptor. This study provides the first evidence that GPR18: Is critical for maintaining endothelial function in muscular, but not elastic, arteries.
Sofie de Moudt +8 more
wiley +1 more source
Advanced Science, Volume 12, Issue 45, December 4, 2025.The chronic glutamate‐induced excitotoxicity hypothesis has profoundly informed the therapeutic strategies employed in Alzheimer’s disease (AD). This study shows pigment epithelium‐derived factor (PEDF) regulates astrocytic glutamate transporter‐1 (GLT‐1)‐mediated glutamate homeostasis and cognition. Reduced PEDF correlates with lower Mini‐Mental State
Jin‐Hui Shi +15 more
wiley +1 more source
Advanced Science, Volume 12, Issue 46, December 11, 2025.SCAP/ARDS patients show reduced unsaturated fatty acids (UFAs) but higher PARK7 and lactate in plasma. PARK7 correlates positively with lactate and negatively with UFAs. Pulmonary endothelial cell multi‐omics show FADS1/2 downregulation and impaired PUFA metabolism. Lactate boosts PARK7 via H3K14 lactylation, and PARK7 then restores FADS1/2.
Jian Xu +11 more
wiley +1 more source
Advanced Science, Volume 12, Issue 45, December 4, 2025.This study establishes an efficient oleaginous heterotrophic microalga, Schizochytrium, through chassis optimization and metabolic engineering, significantly enhancing fatty acid titers and productivities. It also identifies a regulatory mechanism that coordinates biomass and lipid synthesis, providing a rational target for metabolic pathway rewiring ...
Fangzhong Wang +7 more
wiley +1 more source
The emerging role of group VI calcium-independent phospholipase A2 in releasing docosahexaenoic acid from brain phospholipids [PDF]
, 2008 Joshua T. Green +2 more
openalex +1 more source
Mfsd2a‐Targeted Therapy for Ischemic Stroke: Mechanisms, Evidence, and Future Prospects
CNS Neuroscience &Therapeutics, Volume 31, Issue 12, December 2025.This graphical abstract illustrates the central role of Mfsd2a in maintaining blood–brain barrier (BBB) integrity under physiological conditions and its dysregulation following ischemic stroke. In the normal brain (left), Mfsd2a is highly expressed on brain microvascular endothelial cells (BMECs), where it inhibits caveolae‐mediated transcytosis and ...
Zhidong He, Jing Sun
wiley +1 more source
Clinical and Translational Discovery, Volume 5, Issue 6, December 2025.Abstract Objective We aimed to determine if omega‐3 fatty acid (FA) supplementation significantly reduces cardiovascular (CV) events in patients with established CV disease or at high CV risk. Methods We conducted a comprehensive literature search on PubMed, Embase and Cochrane CENTRAL.
Jishanth Mattumpuram +11 more
wiley +1 more source
Ecology and Evolution, Volume 15, Issue 12, December 2025.Distribution ranges of cephalopods are expanding worldwide and their abundances are increasing due to ocean warming. Recently, the broadtail shortfin squid Illex coindetii (Ommastrephidae) expanded into the North Sea where it established a successful spawning stock beside the resident veined squid Loligo forbesii (Loliginidae). Stomach content analysis
Hanna Rittinghaus +4 more
wiley +1 more source