Results 191 to 200 of about 96,904 (327)

Interventions for patients with prostate cancer on active surveillance: a narrative review

open access: yesBJU International, Volume 136, Issue 6, Page 990-1001, December 2025.
Objective To examine contemporary evidence supporting non‐surgical interventions for patients with early prostate cancer (PCa) on active surveillance (AS). Methods A literature search was conducted using the databases PubMed, Medline, and Embase in January 2024 to identify relevant articles published from 2011 onwards.
Simran Gill   +7 more
wiley   +1 more source

Resolution of inflammation in pulmonary arterial hypertension, the influence of sex—An IUPHAR immunopharmacology committee review

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 23, Page 5706-5733, December 2025.
Pulmonary arterial hypertension (PAH) is a progressive and life‐threatening disease with limited treatment options. Sex differences are apparent in PAH, specifically in the pathophysiology, prognoses and pharmacological responses of patients. Inflammation and its resolution, which often differ between sexes, are dysregulated in chronic inflammatory ...
Chloe Landy   +5 more
wiley   +1 more source

Microbial and Metabolic Disorders in Cervical Cancer: Structural Insights, Biomarkers, Mechanisms, and Therapeutic Strategies

open access: yesCancer Science, Volume 116, Issue 12, Page 3228-3238, December 2025.
We unravel synergistic mechanisms by which microbial‐host metabolic networks regulate the tumor immune microenvironment and therapy resistance, bridging gaps between microbiota research and cancer metabolism. Identified biomarkers (e.g., Lactobacillus, C8‐ceramide‐1‐phosphate) and therapeutic approaches (e.g., FMT combined with immune checkpoint ...
Hong Tao   +6 more
wiley   +1 more source

Beyond Neuroprostanes: Total Synthesis and Epilipidomic Studies of a Novel Cyclopentenone Metabolite of Docosahexaenoic Acid. [PDF]

open access: yesChemistry
Pavlíčková T   +8 more
europepmc   +1 more source

Janus Kinase Inhibitors During Pregnancy and Adverse Drug Reactions: A Pharmacovigilance Disproportionality Analysis in VigiBase

open access: yesClinical and Translational Science, Volume 18, Issue 12, December 2025.
ABSTRACT Janus kinase inhibitors (JAKIs) are immunomodulatory drugs used for autoimmune and inflammatory conditions. Their potential impact on pregnancy and fetal development remains a concern due to placental transfer and potential disruption of cytokine and growth factor signaling, with limited human data.
Nazanin Abolhassani   +7 more
wiley   +1 more source

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