Results 41 to 50 of about 5,175,931 (319)

Dietary N-3 polyunsaturated fatty acids decrease biliary cholesterol saturation in gallstone disease [PDF]

open access: yes, 1992
Because fatty acid composition of biliary phospholipids influences cholesterol secretion into bile, we investigated whether replacement of n-1 monounsaturated or n-6 polyunsaturated fatty acids with n-3 polyunsaturated fatty acids in biliary ...
Abell   +59 more
core   +1 more source

Ophthalmic Diagnosis and Novel Management of Infantile Refsum Disease with Combination Docosahexaenoic Acid and Cholic Acid

open access: yesCase Reports in Ophthalmological Medicine, 2021
Infantile Refsum disease is a rare peroxisomal biogenesis disorder characterized by impaired alpha-oxidation and accumulation of phytanic acid in the tissues. Patients often present with fundus changes resembling retinitis pigmentosa, developmental delay,
Omar Elghawy   +4 more
doaj   +1 more source

Omega-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid and their mechanisms of action on apolipoprotein B-containing lipoproteins in humans: a review

open access: yesLipids in Health and Disease, 2017
Epidemiological and genetic studies suggest that elevated triglyceride (TG)-rich lipoprotein levels in the circulation increase the risk of cardiovascular disease.
J. Oscarsson, E. Hurt-Camejo
semanticscholar   +1 more source

Evaluation of the impact of genetic polymorphisms in glutathione-related genes on the association between methylmercury or n-3 polyunsaturated long chain fatty acids and risk of myocardial infarction: a case-control study

open access: yesEnvironmental Health, 2011
Background The n-3 polyunsaturated fatty acids eicosapentaenoic acid and docosahexaenoic acid, which are present in fish, are protective against myocardial infarction.
Norberg Margareta   +11 more
doaj   +1 more source

Metabolism and functions of docosahexaenoic acid‐containing membrane glycerophospholipids

open access: yesFEBS Letters, 2017
Omega‐3 (ω‐3) fatty acids (FAs) such as docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) are known to have important roles in human health and disease.
D. Hishikawa   +4 more
semanticscholar   +1 more source

Docosahexaenoic acid: one molecule diverse functions

open access: yesCritical Reviews in Biotechnology, 2017
Docosahexaenoic acid (DHA, C22:6, ω-3) is a highly polyunsaturated omega-3 fatty acid. It is concentrated in neuronal brain membranes, for which reason it is also referred to as a “brain food”. DHA is essential for brain development and function.
M. Hashimoto   +4 more
semanticscholar   +1 more source

Arachidonic Acid and Docosahexaenoic Acid Metabolites in the Airways of Adults With Cystic Fibrosis: Effect of Docosahexaenoic Acid Supplementation

open access: yesFrontiers in Pharmacology, 2019
Cystic fibrosis (CF) is an autosomal recessive disorder, caused by genetic mutations in CF transmembrane conductance regulator protein. Several reports have indicated the presence of specific fatty acid alterations in CF patients, most notably decreased ...
Elisabetta Teopompi   +13 more
doaj   +1 more source

Docosahexaenoic acid promotes photoreceptor differentiation without altering Crx expression [PDF]

open access: yes, 2006
PURPOSE: The precise molecular cues required for photoreceptor development are still unknown. Pax6 and Crx are essential during early retinal development and for photoreceptor differentiation, respectively.
Garelli, Andres   +2 more
core   +2 more sources

Autooxidation of docosahexaenoic acid: analysis of ten isomers of hydroxydocosahexaenoate.

open access: yesJournal of Lipid Research, 1984
Docosahexaenoic acid, an n-3 essential fatty acid, was recently shown to be enzymically converted by platelets, basophils, and liver microsomes into metabolites containing conjugated dienes with allylic hydroxyl groups. To help identify these metabolites,
M VanRollins, R C Murphy
doaj   +1 more source

Lipids at the crossroad of α-synuclein function and dysfunction: Biological and pathological implications [PDF]

open access: yes, 2019
Since its discovery, the study of the biological role ofα-synuclein and its pathologicalimplications has been the subject of increasing interest. The propensity to adoptdifferent conformational states governing its aggregation and fibrillation makes ...
Alza, Natalia Paola   +4 more
core   +1 more source

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