Results 51 to 60 of about 5,212,695 (327)
Hydrophobic Ligand Binding by Zn-α_2-glycoprotein, a Soluble Fat-depleting Factor Related to Major Histocompatibility Complex Proteins [PDF]
, 2001 Zn-alpha2-glycoprotein (ZAG) is a member of the major histocompatibility complex (MHC) class I family of proteins and is identical in amino acid sequence to a tumor-derived lipid-mobilizing factor associated with cachexia in cancer patients.
Bjorkman, Pamela J. +4 more
core +1 more source
Docosahexaenoic acid–mediated, targeted and sustained brain delivery of curcumin microemulsion
Drug Delivery, 2017 We disclose microemulsions (ME) of curcumin (CUR) with docosahexaenoic acid (DHA)-rich oil (CUR DHA ME) for targeted delivery to the brain. MEs of CUR (5 mg/mL) with and without DHA-rich oil (CUR Capmul ME) suitable for intravenous and intranasal ...
Rajshree L. Shinde, P. Devarajan
semanticscholar +1 more source
Docosahexaenoic acid promotes photoreceptor differentiation without altering Crx expression [PDF]
, 2006 PURPOSE: The precise molecular cues required for photoreceptor development are still unknown. Pax6 and Crx are essential during early retinal development and for photoreceptor differentiation, respectively.
Garelli, Andres +2 more
core +2 more sources
Lipids in Health and Disease, 2017 Docosahexaenoic acid (DHA) is present in high concentrations in salmon, herring, and trout. Epidemiologic studies have shown that high dietary consumption of these and other oily fish is associated with reduced rates of myocardial infarction ...
K. Yamagata
semanticscholar +1 more source
Frontiers in Pharmacology, 2019 Cystic fibrosis (CF) is an autosomal recessive disorder, caused by genetic mutations in CF transmembrane conductance regulator protein. Several reports have indicated the presence of specific fatty acid alterations in CF patients, most notably decreased ...
Elisabetta Teopompi +13 more
doaj +1 more source
Animals, 2022 The effect of the g.4290 C>G substitution in the FADS2 gene and g.285 C>T in the FABP4 gene on carcass quality, meat quality, and fatty acid profile of the pectoralis superficialis muscle of 238 male broiler chickens reared up to 45 days of age was ...
Urszula Kaczor +6 more
doaj +1 more source
HEALTH BENEFITS OF DOCOSAHEXAENOIC ACID (DHA) [PDF]
Pharmacological Research, 1999 Docosahexaenoic acid (DHA) is essential for the growth and functional development of the brain in infants. DHA is also required for maintenance of normal brain function in adults. The inclusion of plentiful DHA in the diet improves learning ability, whereas deficiencies of DHA are associated with deficits in learning.
L A, Horrocks, Y K, Yeo
openaire +2 more sources
Autooxidation of docosahexaenoic acid: analysis of ten isomers of hydroxydocosahexaenoate.
Journal of Lipid Research, 1984 Docosahexaenoic acid, an n-3 essential fatty acid, was recently shown to be enzymically converted by platelets, basophils, and liver microsomes into metabolites containing conjugated dienes with allylic hydroxyl groups. To help identify these metabolites,
M VanRollins, R C Murphy
doaj +1 more source
Docosahexaenoic Acid and the Aging Brain [PDF]
The Journal of Nutrition, 2008 The dietary essential PUFA docosahexaenoic acid [DHA; 22:6(n-3)] is a critical contributor to cell structure and function in the nervous system, and deficits in DHA abundance are associated with cognitive decline during aging and in neurodegenerative disease.
Walter J, Lukiw, Nicolas G, Bazan
openaire +2 more sources
Probing the Electrostatic and Steric Requirements for Substrate Binding in Human Platelet-Type 12-Lipoxygenase. [PDF]
, 2019 Human platelet ALOX12 (hALOX12 or h12-LOX) has been implicated in a variety of human diseases. The present study investigates the active site of hALOX12 to more thoroughly understand how it positions the substrate and achieves nearly perfect regio- and ...
Aleem, Ansari Mukhtar +7 more
core +2 more sources