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The Importance Of Docosahexaenoic Acid (DHA) For Child Development
2023Long-chain polyunsaturated fatty acids (LMPIC), such as those of the n-3 family, represented by eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have relevant physiological and biochemical functions in human metabolism and health. DHA, specifically, is a key nutrient for childhood growth and development because of its primary role in the ...
Pedro Rocha Magalhães +5 more
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Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2021
Recent meta-analyses suggest that high eicosapentaenoic acid (EPA, 20:5n-3) supplements may be beneficial in managing the symptoms of major depression. However, brain EPA levels are hundreds-fold lower than docosahexaenoic acid (DHA, 22:6n-3), making the potential mechanisms of action of EPA in the brain less clear.
Adam H, Metherel +3 more
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Recent meta-analyses suggest that high eicosapentaenoic acid (EPA, 20:5n-3) supplements may be beneficial in managing the symptoms of major depression. However, brain EPA levels are hundreds-fold lower than docosahexaenoic acid (DHA, 22:6n-3), making the potential mechanisms of action of EPA in the brain less clear.
Adam H, Metherel +3 more
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Effect of docosahexaenoic acid (DHA) on arachidonic acid metabolism and platelet function
Biochemical and Biophysical Research Communications, 1983Studies from our laboratory have suggested a role for ferrous iron in the metabolism of arachidonic acid and demonstrated that inhibitors of prostaglandin synthesis exert their effect by complexing with the heme group of cyclooxygenase. Docosahexaenoic acid (DHA) is a potent competitive inhibitor of arachidonic acid metabolism by sheep vesicular gland ...
G H, Rao, E, Radha, J G, White
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Docosahexaenoic acid (DHA) and human platelet reactivity
The Journal of Nutritional Biochemistry, 1991This article wil review the evidence to date using human platelets which indicates that docosahexaenoic acid, in addition to the more well-known effects of eicosapentaenoic acid, may contribute to the dampened platelet reactivity observed following fish/fish oil feeding.
Douglas C. Gaudette, Bruce J. Holub
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Docosahexaenoic acid (DHA) and cardiovascular disease risk factors
Prostaglandins, Leukotrienes and Essential Fatty Acids, 2009Numerous epidemiological and controlled interventional trials have supported the health benefits of long-chain omega-3 fatty acids in the form of docosahexaenoic acid (DHA, 22:6n-3) plus eicosapentaenoic acid (EPA, 20:5n-3) from fish and fish oils as well as from algal sources.
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Thraustochytrids as production organisms for docosahexaenoic acid (DHA), squalene, and carotenoids
Applied Microbiology and Biotechnology, 2016Thraustochytrids have been applied for industrial production of the omega-3 fatty acid docosahexaenoic (DHA) since the 1990s. During more than 20 years of research on this group of marine, heterotrophic microorganisms, considerable increases in DHA productivities have been obtained by process and medium optimization.
Inga Marie, Aasen +6 more
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Lipids, docosahexaenoic acid (DHA), and traumatic brain injury
2023Traumatic brain injury (TBI) is one of the leading causes of death or disability in incidents of trauma. It continues to be clinically challenging to find absolute treatments that can manage and control all aspects of secondary injury post-TBI. While some fat diets, like high-fat diet (HFD), are bad, emerging evidence suggests that early treatment with
Darwish, Batoul +4 more
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Docosahexaenoic acid (DHA) production by Thraustochytrium sp. ATCC 20892
World Journal of Microbiology and Biotechnology, 1996Thraustochytrium sp. ATCC 20892 produced high yields of docosahexaenoic acid (DHA), more than four other strains of Thraustochytrium and Schizochytrium tested, but insignificant amounts of other polyunsaturated fatty acids. Glucose and sodium glutamate were the preferred carbon and nitrogen sources, respectively, and the optimum conditions for growth ...
A, Singh, S, Wilson, O P, Ward
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Maternal docosahexaenoic acid (DHA) supplementation and fetal DHA accretion
2001Docosahexaenoic acid (DHA) (C22;6n-3) is a polyunsaturated fatty acid that is an essential constituent of cell membranes, particularly of the nervous system where it is found in relatively high concentrations in the brain and retina. In this study expectant mothers were supplied with preformed DHA, at a dosage comparable with current dietary ...
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Effect of Docosahexaenoic Acid (DHA) on Spinal Cord Injury
2016Spinal cord injury (SCI) has become one of the most leading concerns in the past decade. Preclinical and research studies are now ongoing trying to understand the molecular mechanisms and develop treatment strategies for this neurodegenerative condition.
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