Results 11 to 20 of about 2,701,337 (214)

Dietary docosahexaenoic acid (DHA) downregulates liver DHA synthesis by inhibiting eicosapentaenoic acid elongation

Journal of Lipid Research
DHA is abundant in the brain where it regulates cell survival, neurogenesis, and neuroinflammation. DHA can be obtained from the diet or synthesized from alpha-linolenic acid (ALA; 18:3n-3) via a series of desaturation and elongation reactions occurring ...
Adam H. Metherel, Rodrigo Valenzuela, Brinley J. Klievik, Giulia Cisbani, Ruxandra D. Rotarescu, Melissa Gonzalez-Soto, Céline Cruciani-Guglielmacci, Sophie Layé, Christophe Magnan, David M. Mutch, Richard P. Bazinet   +10 more
doaj   +5 more sources

Docosahexaenoic acid: membrane modification and neurotrophic mechanisms

Oléagineux, Corps gras, Lipides, 2011
Docosahexaenoic acid (DHA, 22:6n-3) is highly enriched in the brain mainly in membrane phospholipids. Maintenance of a high DHA concentration in brain is essential for proper neuronal function, suggesting a unique requirement of this fatty acid for an ...
Kim Hee-Yong
doaj   +2 more sources

Human Milk: Fast Determination of Docosahexaenoic Acid (DHA)

Analytica, 2023
Human milk provides all the nutrients required by babies during the first six months of their life. Human milk lipids represent the main source of energy, contributing almost 50% of the total energy content.
Mahyara Markievicz Mancio Kus-Yamashita, Cristiane Bonaldi Cano, Vânia Claudia Barros Monteiro, Regina Maria Catarino   +3 more
doaj   +2 more sources

Combined application of eicosapentaenoic acid and docosahexaenoic acid on depression in women: a meta-analysis of double-blind randomized controlled trials

Neuropsychiatric Disease and Treatment, 2015
Jia-run Yang, Dong Han, Zheng-xue Qiao, Xue Tian, Dong Qi, Xiao-hui QiuDepartment of Medical Psychology, Public Health Institute of Harbin Medical University, Harbin, Heilongjiang Province, People’s Republic of ChinaObjectives: Previous randomized ...
Yang JR, Han D, Qiao ZX, Tian X, Qi D, Qiu XH   +5 more
doaj   +1 more source

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

Hepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario, David Sebastián, Mireia Casulleras, Marta Duran‐Güell, Roger Flores‐Costa, Ferran Aguilar, Juan José Lozano, Ingrid W. Zhang, Esther Titos, Jing X. Kang, Antonio Zorzano, Makoto Arita, Joan Clària   +12 more
wiley   +1 more source

Docosahexaenoic acid (DHA) and hepatic gene transcription [PDF]

Chemistry and Physics of Lipids, 2008
The type and quantity of dietary fat ingested contributes to the onset and progression of chronic diseases, like diabetes and atherosclerosis. The liver plays a central role in whole body lipid metabolism and responds rapidly to changes in dietary fat composition.
Jump, D.B., Botolin, D., Wang, Y., Xu, J., Demeure, Olivier, O., Christian, B.   +5 more
openaire   +3 more sources

Engineering docosapentaenoic acid (DPA) and docosahexaenoic acid (DHA) in Brassica juncea [PDF]

Plant Biotechnology Journal, 2021
Omega-3 long chain polyunsaturated fatty acids (ω3 LC-PUFAs) such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are important for human health. Sub-optimal levels of ω3 LC-PUFAs are associated with increased risk of several diseases (Ghasemi Fard et al., 2019).
Srinivas Belide, Pushkar Shrestha, Yoko Kennedy, Antonio Leonforte, Malcolm D. Devine, James R. Petrie, Surinder P. Singh, Xue‐Rong Zhou   +7 more
openaire   +2 more sources

Oxidation of an oil rich in docosahexaenoic acid compared to linoleic acid in lactating women [PDF]

, 1999
Background: We studied the oxidation of an oil rich in docosahexaenoic acid (DHA; DHASCO(R)) in lactating mothers receiving a dietary DHA supplement or a placebo. The results were compared with the oxidation of linoleic acid.
Pohl, A., Sauerwald, T., Koletzko, Berthold, Fidler, N., Demmelmair, Hans   +4 more
core   +1 more source

Breastfeeding, the use of docosahexaenoic acid-fortified formulas in infancy and neuropsychological function in childhood [PDF]

, 2010
Objective: To investigate the relation between breastfeeding, use of docosahexaenoic acid (DHA)-fortified formula and neuropsychological function in children. Design Prospective cohort study. Setting Southampton, UK.
West, Carolyn, Limond, Jennifer, Gale, Catharine R., Gale, Catherine R., Cooper, Cyrus, Robinson, Sian M., Marriott, Lynne D., Godfrey, Keith M., Law, Catherine M, Inskip, Hazel M, Martyn, Christopher N., Martyn, Christopher N, Marriott, Lynne D, Inskip, Hazel M., Godfrey, Keith M, ?, ?, Robinson, Siân M, West, C, J. Limond, C. Cooper, Gale, CR, S. M Robinson, C. R Gale, Martyn, CN, Limond, J, Marriott, LD, Inskip, HM, L. D Marriott, H. M Inskip, Law, CM, Godfrey, KM, C. West, K. M Godfrey, Robinson, SM, C. M Law, null null, C. N Martyn   +36 more
core   +1 more source

Breast milk docosahexaenoic acid (DHA) correlates with DHA status of malnourished infants [PDF]

Archives of Disease in Childhood, 2000
To investigate whether low docosahexaenoic acid (22:6omega3; DHA) status of malnourished, mostly breast fed infants is a result of low omega3 fatty acid intake via breast milk.Fatty acid composition of breast milk of eight Pakistani mothers, and of the erythrocytes of their malnourished children was analysed.The milk of the Pakistani mothers contained ...
Smit, EN, Oelen, EA, Seerat, E, Muskiet, FAJ, Boersma, ER   +4 more
openaire   +2 more sources