Results 131 to 140 of about 18,832,580 (328)

Structure of the Epidermal Growth Factor Receptor Kinase Domain Alone and in Complex with a 4-Anilinoquinazoline Inhibitor*

open access: yesJournal of Biological Chemistry, 2002
The crystal structure of the kinase domain from the epidermal growth factor receptor (EGFRK) including forty amino acids from the carboxyl-terminal tail has been determined to 2.6-Å resolution, both with and without an EGFRK-specific inhibitor currently ...
J. Stamos, M. Sliwkowski, C. Eigenbrot
semanticscholar   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Low-temperature demagnetization of volcanic rocks containing multi-domain magnetic grains: Implications for the Thellier paleointensity determination [PDF]

open access: yesGeofísica Internacional, 2001
Thirteen samples of volcanic rocks from Caucasus, Iceland and Philippines were subjected to low-temperature treatment in order to remove the part of remanent magnetization carried by multi-domain grains. Ten to 40% of multi-domain partial thermoremanence
Ana-María Soler   +3 more
doaj  

Domain structure of epitaxial Co films with perpendicular anisotropy

open access: yes, 2008
Epitaxial hcp Cobalt films with pronounced c-axis texture have been prepared by pulsed lased deposition (PLD) either directly onto Al2O3 (0001) single crystal substrates or with an intermediate Ruthenium buffer layer.
A. Hubert   +6 more
core   +1 more source

Vortex Domain Structure in Ferroelectric Nanoplatelets and Control of its Transformation by Mechanical Load

open access: yesScientific Reports, 2012
Vortex domain patterns in low-dimensional ferroelectrics and multiferroics have been extensively studied with the aim of developing nanoscale functional devices.
Wenfang Chen, Yue Zheng, Biao Wang
semanticscholar   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor

open access: yesNature, 2020
J. Lan   +10 more
semanticscholar   +1 more source

Mapping the moral domain.

open access: yesJournal of Personality and Social Psychology, 2011
The moral domain is broader than the empathy and justice concerns assessed by existing measures of moral competence, and it is not just a subset of the values assessed by value inventories.
J. Graham   +5 more
semanticscholar   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

DOMAIN CONTRIBUTION TO THE DIELECTRIC PROPERTIES OF THE CRYSTALS OF TRIGLYCINE SULPHATE GROUP AND ROCHELLE SALT

open access: yesКонденсированные среды и межфазные границы, 2017
The dielectric properties of the crystals of nominally pure triglycine sulphate (TGS), deuterated TGS, TGS doped with L,α – alanine, TGS with impurity of phosphorus P5+ ions, TGS subjected to X-ray radiation as well as of Rochelle salt crystal were ...
Golitsyna Olga M.   +3 more
doaj   +1 more source

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