Results 111 to 120 of about 37,774 (258)

Limited donepezil inhibition of acetylcholinesterase measured with positron emission tomography in living Alzheimer cerebral cortex [PDF]

, 2000
David E. Kuhl, Satoshi Minoshima, Kirk A. Frey, Norman L. Foster, Michael R. Kilbourn, Robert A. Koeppe   +5 more
openalex   +1 more source

Therapeutic Effect of Donepezil on Neuroinflammation and Cognitive Impairment after Moderate Traumatic Brain Injury

Life
Background: Despite the important clinical issue of cognitive impairment after moderate traumatic brain injury (TBI), there is currently no suitable treatment.
Dong Hyuk Youn, Younghyurk Lee, Sung Woo Han, Jong-Tae Kim, Harry Jung, Gui Seung Han, Jung In Yoon, Jae Jun Lee, Jin Pyeong Jeon   +8 more
doaj   +1 more source

Continuation rates of newly prescribed donepezil among patients with Alzheimer’s disease in Japan: Life study [PDF]

, 2023
Haruhisa Fukuda, Megumi Maeda, Fumiko Murata   +2 more
openalex   +1 more source

Comparison of In Silico AChE Inhibitory Potentials of Some Donepezil Analogues

Pharmata
Cholinesterases are important in ensuring hemostasis in our body. Excessive increase in cholinesterase function causes various cholinergic dysfunctions. Alzheimer's is a disease characterized by loss of cholinergic activity, which is especially common in
Mehmet Koca
doaj  

Effect of concomitant use of yokukansan on steady‐state blood concentrations of donepezil and risperidone in real‐world clinical practice

Neuropsychopharmacology Reports
Aim Yokukansan is one of the most frequently used herbal medicines that can improve the behavioral and psychological symptoms of dementia. In this exploratory study, we investigated whether yokukansan affects the steady‐state blood concentrations of ...
Junji Saruwatari, Tetsuya Kaneko, Tsukasa Murata, Haruka Narise, Sawa Kugimoto, Eri Nishimura, Natsuki Tetsuka, Misaki Ando, Momo Oi, Masako Ota, Nayumi Hamada, Keiichiro Kaneda, Shiro Furusho, Masakatsu Sakamoto, Ayami Kajiwara‐Morita, Kazutaka Oda, Kentaro Oniki, Keishi Ueda, Hirofumi Jono, Norio Yasui‐Furukori   +19 more
doaj   +1 more source

Single dose pharmacokinetics of the novel transdermal donepezil patch in healthy volunteers

Drug Design, Development and Therapy, 2015
Yo Han Kim,1 Hee Youn Choi,1 Hyeong-Seok Lim,1 Shi Hyang Lee,1 Hae Sun Jeon,1 Donghyun Hong,2 Seong Su Kim,2 Young Kweon Choi,2 Kyun-Seop Bae1 1Department of Clinical Pharmacology and Therapeutics, College of Medicine, University of Ulsan, Asan Medical ...
Kim YH, Choi HY, Lim HS, Lee SH, Jeon HS, Hong D, Kim SS, Choi YK, Bae KS   +8 more
doaj  

Revisiting the Metabolism of Donepezil in Rats Using Non-Targeted Metabolomics and Molecular Networking

Pharmaceutics
Background/Objectives: Although donepezil, a reversible acetylcholinesterase inhibitor, has been in use since 1996, its metabolic characteristics remain poorly characterized.
Eun-Ji Park, Eui-Hyeon Kim, Ki-Young Kim, Ji-Hyeon Jeon, Im-Sook Song, So-Young Park, Kwang-Hyeon Liu   +6 more
doaj   +1 more source

Perifériás markerek jelentősége Alzheimer-kór diagnózisában és terápiájában = Peripheral markers in the diagnosis and the therapy of Alzheimer`s disease [PDF]

, 2006
A legjelentősebb neurokémiai abnormalitás az Alzheimer-kórban (AK) a központi idegrendszer kolinerg rendszerének csökkent működése, de feltehetőleg a perifériás szövetek is érintettek lehetnek.
Kálmán, János, Rakonczay, Zoltán
core  

Preventing the Unnecessary Losses of Alzheimer\u27s Disease [PDF]

, 1998
Educational Objectives 1. To state the importance of early detection and diagnosis of Alzheimer\u27s disease. 2. To describe common concerns of people in the early stages of Alzheimer\u27s disease. 3.
Noyes, Lin E.
core   +1 more source

Donepezil Beyond Alzheimer's Disease? A Narrative Review of Therapeutic Potentials of Donepezil in Different Diseases [PDF]

, 2022
Parham Pooladgar, Mehdi Sakhabakhsh, Arsia Taghva, Saeed Soleiman-Meigooni   +3 more
openalex   +1 more source