Abstract Background Transcranial temporal interference stimulation (TIs) targeting the subthalamic nucleus (STN) is a novel noninvasive neuromodulation approach with potential to improve motor symptoms in Parkinson's disease (PD). However, its underlying neuroimaging mechanisms remain unclear.
Yongxin Xu +19 more
wiley +1 more source
Assessment of striatal and extrastriatal [<sup>18</sup>F]fluoroDOPA uptake by a Silicon Photomultiplier PET camera in Parkinson's disease. [PDF]
Darcourt J +4 more
europepmc +1 more source
Distinct Brain Drivers and Shared Cerebello–Cortical Input in ADCY5 and SGCE Hyperkinetic Movements
Resting‐state fMRI and effective connectivity revealed distinct cerebellar–basal ganglia–cortical interactions in ADCY5 (MxMD‐ADCY5) and SGCE (MYC/DYT‐SGCE) related movement disorders. The cerebellum modulated cortex directly in MYC/DYT‐SGCE, but indirectly via basal ganglia‐cerebellar projections in MxMD‐ADCY5, which also showed reduced subthalamic ...
Clément Tarrano +33 more
wiley +1 more source
Drug-Induced Parkinsonism: A Structured, Mechanism-Informed Approach to Identification and Management. [PDF]
De Faria Sousa B, Espinosa JB.
europepmc +1 more source
Volunteer studies replacing animal experiments in brain research - Report and recommendations of a Volunteers in Research and Testing workshop [PDF]
Harding, G +8 more
core
Mechanistic Insights of Zonisamide in Parkinson's Disease: A Systematic Review
ABSTRACT Zonisamide is an antiepileptic agent used as adjunctive therapy for Parkinson's Disease in Japan and studied more selectively elsewhere. Preclinical and early translational studies suggest that zonisamide may modulate several pathways relevant to Parkinson's Disease pathobiology, including dopaminergic neurotransmission, oxidative stress ...
Justin Kim +3 more
wiley +1 more source
Mutational effects of the asparagine198 and glutamate223 residues on the human norepinephrine transporter on basal and HIV-1 Tat protein-induced inhibition of dopamine transport. [PDF]
Porter KD +8 more
europepmc +1 more source
Breakdown of C3 complement and IgG in peritonitis exudate-pathophysiological aspects and therapeutic approach [PDF]
Billing, A. +5 more
core
Review of nutrition management of pediatric intestinal pseudo‐obstruction
Abstract Chronic intestinal pseudo‐obstruction (CIPO) is a rare, heterogeneous, and debilitating disorder characterized by profound intestinal dysmotility and severe nutrition challenges. Its presentation resembles that of mechanical bowel obstruction, but CIPO occurs in the absence of luminal obstruction.
Senthilkumar Sankararaman +5 more
wiley +1 more source
Biomimetic nanovesicles decorated with chemotactic and target membrane proteins for lupus nephritis treatment. [PDF]
Gan J, Huang D, Liu R, Zhao Y, Sun L.
europepmc +1 more source

