Results 201 to 210 of about 199,386 (303)

Managing Dystonia in Partington Syndrome

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Bilateral focal hand dystonia is an almost pathognomonic sign of Partington syndrome, frequently accompanied by intellectual disability and oromotor dyspraxia. However, a few studies have focused on the treatment of this focal dystonia, making patient management uncertain.
Emilie Pichon, Aurea Alioth, Sabina Catalano Chiuvé, André Zacharia, Marta Ruiz‐Lopez, David P. Breen, Florence Zangas‐Gehri, Florent Draye, Aurore Curie, Duncan Wilson, Victor S.C. Fung, Stephen Duma, Joël Fluss, Julien F. Bally   +13 more
wiley   +1 more source

Dopaminergic neuron differentiation with different starting cell types or media.

Kevin R. Yi (15145323), Jac-Leen S.S. Nash (21601140), Mark G. Carter (15145311), Danica M. Walkley (15145317), Jiwon Jang (7435394), Benoit J. Smagghe (45223), Andrew K. Stewart (15145326), Cynthia C. Bamdad (15145308)   +7 more
openalex   +1 more source

Prognostic Value of Parkinson's Disease Subtypes in the LABS‐PD Cohort: Functional Ability, Quality of Life and Mortality

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Research on Parkinson's disease (PD) heterogeneity may inform clinical prognosis. There is currently no fully validated PD subtype classification system. Objectives We aimed at assessing the prognostic relevance of a data‐driven PD subtype classification system.
Deepa Dash, Shirley Eberly, David Oakes, David Grimes, Anthony E. Lang, Caroline Tanner, Tiago A. Mestre, Connie Marras   +7 more
wiley   +1 more source

High Cerebrospinal DOPA Decarboxylase Level Predicts Cognitive Decline in Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Abstract Background DOPA decarboxylase (DDC) in cerebrospinal fluid (CSF) is an emerging Parkinson's disease (PD) biomarker, but its association with nonmotor symptoms is unclear. Objectives We aimed to determine if baseline DDC was associated with future cognitive decline in PD.
Andrea Sturchio, Wojciech Paslawski, Shervin Khosousi, Ioanna Markaki, Michael A. Nalls, Andrew B. Singleton, Hirotaka Iwaki, Per Svenningsson   +7 more
wiley   +1 more source

Polyhalogenated Carbazole Impairs Dopaminergic Neurons through Dysregulation of Liquid-Liquid Phase Separation in Caenorhabditis elegans. [PDF]

Adv Sci (Weinh)
Luo Y, Xu H, Peng P, Lu X, Zhou Q, Gao Z, Tang C, Yin H, Cai Y, Mahai G, Zhu Z, Liu Z, Li H, Xu S.   +13 more
europepmc   +1 more source

Transcriptional regulation of proapoptotic kinase PKCδ expression in dopaminergic neurons: relevance to gene-gene and gene-environment interactions in neurodegeneration

, 2010
Huajun Jin
openalex   +2 more sources

Discrepant Views of Apathy in Patients and Caregivers: the Role of Cognitive Deficits in Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Apathy is a common early symptom of Parkinson's disease (PD), often co‐occurring with cognitive decline and associated with fronto‐striatal and mesocortico‐limbic dysfunctions. Discrepancies between self‐ and caregiver‐reported apathy have been preliminarily associated with cognitive impairments affecting patients’ awareness and ...
Giulia Funghi, Francesca Fabris, Claudia Meli, Chiara Speranza, Giuseppe Rabini, Giorgio Giulio Fumagalli, Francesca Zappini, Selene Schintu, Raffaella Di Giacopo, Stefano Tambalo, Luca Turella, Jorge Jovicich, Costanza Papagno, Alessandra Dodich   +13 more
wiley   +1 more source

Unraveling the mystery: How autophagy deficiency in dopaminergic neurons drives human Parkinson's disease. [PDF]

Mol Brain
Noda S, Hattori N.
europepmc   +1 more source

Basal Forebrain Volume and Concurrent Hallucinations and Mild Cognitive Impairment in Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Visual hallucinations (VH) and mild cognitive impairment (MCI) often co‐occur in Parkinson's Disease (PD). Each symptom in isolation is associated with cholinergic basal forebrain (BF) atrophy. However, it is unclear whether BF integrity relates to one symptom preferentially or to their co‐occurrence, and whether this relationship ...
Sabrina M. Adamo, Vaishali Mutreja, Marta Statucka, Batu Kaya, Taylor W. Schmitz, Anthony C. Ruocco, Melanie Cohn   +6 more
wiley   +1 more source

Optogenetic stimulation of midbrain dopaminergic neurons rescues hippocampal synaptic plasticity deficits in a mouse model of Alzheimer's disease. [PDF]

Transl Psychiatry
Ficchì S, Cauzzi E, La Barbera L, De Paolis ML, Loffredo G, Spoleti E, Ferrari I, Saba L, Biamonte F, Nobili A, Krashia P, D'Amelio M.   +11 more
europepmc   +1 more source