Results 201 to 210 of about 181,607 (254)

Dopaminergic neurons in the human retina [PDF]

open access: possibleJournal of Comparative Neurology, 1982
AbstractThe utilization of dopamine in the adult human retina was examined by using high‐affinity uptake, localization, synthesis, and release as neurotransmitter‐specific physiological probes. Autoradiographic and histochemical studies have shown that dopamine‐accumulating and dopamine‐containing cells of the human retina belong to a population of ...
Mary E. Rayborn   +4 more
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Dopaminergic neurons

The International Journal of Biochemistry & Cell Biology, 2005
Dopaminergic neurons of the midbrain are the main source of dopamine (DA) in the mammalian central nervous system. Their loss is associated with one of the most prominent human neurological disorders, Parkinson's disease (PD). Dopaminergic neurons are found in a 'harsh' region of the brain, the substantia nigra pars compacta, which is DA-rich and ...
Julie K. Andersen, Shankar J. Chinta
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Dopaminergic neurons for Parkinson's therapy [PDF]

open access: possibleNature Biotechnology, 2012
A differentiation protocol guided by developmental principles produces more-authentic dopaminergic neurons for transplantation in patients.
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Dopaminergic neurons intrinsic to the striatum

Journal of Neurochemistry, 2007
AbstractThe striatum – the largest integrative component of the basal ganglia – harbors a population of neurons that express the enzyme tyrosine hydroxylase (TH), a faithful marker of dopaminergic neurons. The dopaminergic nature of these neurons is further supported by the fact that they express the dopamine (DA) transporter (DAT) and the nuclear ...
André Parent, Philippe Huot
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Toxicity of semaphorin3A for dopaminergic neurons

Neuroscience Letters, 2005
Semaphorin3A (Sema3A) is known to cause neuronal apoptosis and serves as a chemorepellent factor for axonal growth. In our previous report, we found that Sema3A was up-regulated in the 6-OHDA-injected striatum of rats, suggesting that Sema3A was likely involved in dopaminergic (DA) depletion.
Isao Date   +11 more
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A Diet for Dopaminergic Neurons?

2009
Parkinson's disease (PD) is the second most common neurodegenerative disease, which unfortunately is still fatal. Since the discovery of dopamine (DA) neuronal cell loss within the substantia nigra in PD, the past decades have seen the understanding of the pathophysiological mechanisms underlying the degenerative process advance at a very impressive ...
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ELECTROPHYSIOLOGICAL EFFECTS OF AMPHETAMINE ON DOPAMINERGIC NEURONS

Biochemical Pharmacology, 1973
Publisher Summary This chapter elaborates the electrophysiological effects of amphetamine on dopaminergic neurons. Antipsychotic phenothiazines and haloperidol were shown to reverse, and block the depressant effect of d-AMP. In addition, one found that blockade of DA synthesis by the intra-peritoneal administration of 50 mg/kg of the tyrosine ...
George K. Aghajanian, Benjamin S. Bunney
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Noradrenergic Modulation on Dopaminergic Neurons

Neurotoxicity Research, 2018
It is now well accepted that there is a close relationship between noradrenergic and dopaminergic neurons in the brain, especially referring to the modulation of the locus coeruleus-norepinephrine (LC-NE) system on dopamine transmission. The disturbance of this modulation may contribute to neurodegeneration of dopaminergic neurons in Parkinson's ...
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