Results 211 to 220 of about 835,318 (379)
Myoclonic Dystonia: A Common Phenomenology in the Pleomorphic Movements of Angelman Syndrome
Abstract Background Angelman syndrome (AS) is a neurodevelopmental disorder characterized by developmental delay, intellectual disability, a sociable demeanor, and abnormal movements. People with AS often exhibit multiple types of abnormal movements, including nonepileptic myoclonus, tremor, and dystonia, which hamper attempts to identify phenomenology
Robert P. Carson+8 more
wiley +1 more source
The effect of cannabinoid type Ⅱ receptor on the excitability of substantia nigra dopaminergic neurons. [PDF]
Zhao S, Liu S, Gong Y, Ma Z.
europepmc +1 more source
Evidence of Involvement of the Calcitonin Gene‐Related Peptide in Restless Legs Syndrome
Abstract Background Restless legs syndrome (RLS) is a common sensory‐motor disorder characterized by an urge to move the legs, often with unpleasant sensations, particularly during rest. Current treatments include iron supplementation, dopamine agonists, and opioids, but new therapeutic approaches are needed.
Maria P. Mogavero+8 more
wiley +1 more source
Spatiotemporal proteomic and transcriptomic landscape of DAT+ dopaminergic neurons development and function. [PDF]
Zhao H+5 more
europepmc +1 more source
Optic Disc Pallor in Parkinson's Disease: A UK Biobank Study
Abstract Background Recent studies have suggested that retinal changes measured with optical coherence tomography are detectable in early Parkinson's disease (PD), highlighting the potential of ophthalmic biomarkers for diagnosis and monitoring. Objective We set out to investigate the relationship between optic disc pallor measured in fundoscopy images
Samuel Gibbon+3 more
wiley +1 more source
Highlights Metformin activates GDF15 expression, which reduces appetite with induction of weight loss in both diabetic and non‐diabetic patients. GDF15 level is linked and correlated with the progression of diabetic complications including thrombosis, diabetic nephropathy, diabetic neuropathy, and diabetic retinopathy. Abstract Type 2 diabetes mellitus
Hayder M. Al‐kuraishy+8 more
wiley +1 more source
Abstract Background Temporal interference stimulation (TIS) is a novel noninvasive electrical stimulation technique to focally modulate deep brain regions; a minimum of two high‐frequency signals (f1 and f2 > 1 kHz) interfere to create an envelope‐modulated signal at a deep brain target with the frequency of modulation equal to the difference frequency:
Martin Lamoš+16 more
wiley +1 more source
Nanodiamond-mediated delivery of microRNA-7 for the neuroprotection of dopaminergic neurons. [PDF]
Han Y, Yao Y, Wen X, Wang H, Li S, Su B.
europepmc +1 more source