Results 21 to 30 of about 39,387 (246)

Positive selection underlies Faster-Z evolution of gene expression in birds. [PDF]

open access: yes, 2015
The elevated rate of evolution for genes on sex chromosomes compared to autosomes (Fast-X or Fast-Z evolution) can result either from positive selection in the heterogametic sex, or from non-adaptive consequences of reduced relative effective population ...
Dean, R   +4 more
core   +1 more source

Conditional knockdown of transformer in sheep blow fly suggests a role in repression of dosage compensation and potential for population suppression.

open access: yesPLoS Genetics, 2021
The transformer (tra) gene is essential for female development in many insect species, including the Australian sheep blow fly, Lucilia cuprina. Sex-specific tra RNA splicing is controlled by Sex lethal (Sxl) in Drosophila melanogaster but is auto ...
Megan E Williamson   +2 more
doaj   +1 more source

THE GENETIC BASIS OF DOSAGE COMPENSATION OF ALCOHOL DEHYDROGENASE-1 IN MAIZE [PDF]

open access: yesGenetics, 1981
ABSTRACT The levels of alcohol dehydrogenase (ADH) do not exhibit a structural gene-dosage effect in a one to four dosage series of the long arm of chromosome one (1L) (BIRCHLER19 79). This phenomenon, termed dosage compensation, has been studied in more detail.
openaire   +2 more sources

Massive gene amplification on a recently formed Drosophila Y chromosome. [PDF]

open access: yes, 2019
Widespread loss of genes on the Y is considered a hallmark of sex chromosome differentiation. Here we show that the initial stages of Y evolution are driven by massive amplification of distinct classes of genes. The neo-Y chromosome of Drosophila miranda
Bachtrog, Doris   +2 more
core   +1 more source

Single-molecule long-read sequencing reveals the potential impact of posttranscriptional regulation on gene dosage effects on the avian Z chromosome

open access: yesBMC Genomics, 2022
Background Mammalian sex chromosomes provide dosage compensation, but avian lack a global mechanism of dose compensation. Herein, we employed nanopore sequencing to investigate the genetic basis of gene expression and gene dosage effects in avian Z ...
Jianmei Wang   +9 more
doaj   +1 more source

X-chromosome target specificity diverged between dosage compensation mechanisms of two closely related Caenorhabditis species

open access: yeseLife, 2023
An evolutionary perspective enhances our understanding of biological mechanisms. Comparison of sex determination and X-chromosome dosage compensation mechanisms between the closely related nematode species Caenorhabditis briggsae (Cbr) and Caenorhabditis
Qiming Yang   +6 more
doaj   +1 more source

Genetic Analysis of X-Chromosome Dosage Compensation in Caenorhabditis elegans

open access: yesGenetics, 1987
ABSTRACT We have shown that the phenotypes resulting from hypomorphic mutations (causing reduction but not complete loss of function) in two X-linked genes can be used as a genetic assay for X-chromosome dosage compensation in Caenorhabditis elegans between males (XO) and hermaphrodites (XX).
Meneely, Philip M., Wood, W. B.
openaire   +2 more sources

Resistance risk assessment of the novel complex II inhibitor pyflubumide in the polyphagous pest Tetranychus urticae [PDF]

open access: yes, 2020
Pyflubumide is a novel selective carboxanilide acaricide that inhibits mitochondrial complex II of spider mite species such as Tetranychus urticae. We explored the baseline toxicity and potential cross-resistance risk of pyflubumide in a reference panel ...
Fotoukkiaii, Seyedeh Masoumeh   +3 more
core   +1 more source

General lack of global dosage compensation in ZZ/ZW systems? Broadening the perspective with RNA-seq

open access: yesBMC Genomics, 2011
Background Species with heteromorphic sex chromosomes face the challenge of large-scale imbalance in gene dose. Microarray-based studies in several independent male heterogametic XX/XY systems suggest that dosage compensation mechanisms are in place to ...
Wolf Jochen BW, Bryk Jarosław
doaj   +1 more source

Mutations in the transcription elongation factor SPT5 disrupt a reporter for dosage compensation in Drosophila.

open access: yesPLoS Genetics, 2012
In Drosophila, the MSL (Male Specific Lethal) complex up regulates transcription of active genes on the single male X-chromosome to equalize gene expression between sexes.
Mahalakshmi Prabhakaran   +1 more
doaj   +1 more source

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