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An improved method for the detection of double-stranded RNA suitable for quality control of mRNA vaccines. [PDF]

open access: yesProtein Cell
Liu J   +9 more
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Double stranded RNA sensing drives interferon silencing in early development

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Witteveldt J   +11 more
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Double-stranded RNA

Molecular and Cellular Biochemistry, 1980
High molecular weight, fully double-stranded RNA (dsRNA) has been recognized as the genetic material of many plant, animal, fungal, and bacterial viruses (Diplornaviruses): virusspecific dsRNA is also found in cells infected with single-stranded RNA viruses.
LIBONATI M.   +2 more
openaire   +3 more sources

The Replication of Double-Stranded RNA

1986
A wide variety of fungi harbor virus-like particles (VLPs), approximately 40 nm in diameter, that contain double-stranded RNA (dsRNA) genomes (10). In some ways, these dsRNA genomes are more similar to plasmids than to true viruses. They are noninfectious and are transferred between cells only under conditions of cytoplasmic mixing, such as occurs in ...
A M, Newman, C S, McLaughlin
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The anti‐virus activity of double‐stranded RNA in the presence of antibody to double‐stranded RNA

European Journal of Immunology, 1974
AbstractMice were given double‐stranded RNA from a fungal source either in saline or emulsified in Freund's complete adjuvant. In each case the animals produced antibodies specific for double‐stranded RNA.Mice immunized in this way were as well protected against infection with encephalomyocarditis virus following a subsequent injection of double ...
J D, Naysmith   +2 more
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Cellular response to double‐stranded RNA

Journal of Cellular Biochemistry, 1991
AbstractThe study of double‐stranded RNA (dsRNA) encompasses a variety of fields. Basic research in this area has contributed to a greater mechanistic understanding of gene induction, tumor cell growth arrest, the establishment of antiviral states, and immunomodulation.
D S, Haines   +2 more
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Double-Stranded Viral RNA

1969
Publisher Summary The pace of research on RNA virus replication and the huge amount of related literature that has accumulated in the past 6 years attest to the wide interest in the topic. There has also been some controversy and apparent confusion, probably largely because of pressure for publication priority. In this chapter, methods for detecting,
openaire   +2 more sources

Double-stranded RNA of Ibaraki virus

Virology, 1977
Abstract The Ibaraki virus RNA is double-stranded. The base composition of the RNA is 27.7% A, 27.1% U, 23.0% G, and 22.2% C. Ibaraki virus is classified as belonging to the orbivirus genus of the family Reoviridae.
Y, Suzuki, Y, Saito, S, Nakagawa
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