Results 211 to 220 of about 2,380,289 (248)

Direct Cloning of Double-Stranded RNAs

2015
Most annotated genomes show a large number of sense-antisense transcripts that can generate double-stranded RNAs. We describe a method to clone these dsRNAs from total RNA preparations.
Manli, Shen, Marina, Falaleeva, Natalia, Korotkova, Stefan, Stamm   +3 more
openaire   +2 more sources

Herpes-virus and double-stranded RNA

Experientia, 1973
On a cherche a determiner la presence d'un ARN bi-cat\'enaire lors de la r\'eplication du virus herp\'etique. La pr\'ecipitation de LiCl 2M, la filtration sur gel Sephadex, la chromatographie sur cellulose, la s\'edimentation en gradient de densit\'e et l'induction d'interf\'eron in vivo et in vitro semblent d\'emontrer qu'une telle structure n'est pas
R, Perez-Bercoff, G, Carrara, A, Dolei, G, Rita   +3 more
openaire   +2 more sources

Assembly of Double‐Stranded RNA Bacteriophages

2005
Publisher Summary This chapter focuses on bacteriophage O6. Most of the current knowledge about the structure, assembly, and molecular biology of double stranded (ds) RNA bacteriophages is derived from model systems. It is found that the assembly of enveloped dsRNA bacteriophages can be dissected into four distinct steps: assembly of empty precursor ...
Minna M, Poranen, Roman, Tuma, Dennis H, Bamford   +2 more
openaire   +2 more sources

Double-Stranded RNAs as Gene Activators

1994
In 1963 Gomatos and Tamm discovered the first natural dsRNA, namely the genomic RNA of reoviruses. A few years later, Lampson et al. (1967) established that dsRNA is the active agent in an extract of a Penicillium funiculosum preparation which, following injection into rabbits, induces interferon (IFN) in serum. They also showed that various natural (i.
S, Landolfo, M, Gariglio, G, Gribaudo, G, Garotta   +3 more
openaire   +2 more sources

Gene silencing by double-stranded RNA

Current Opinion in Cell Biology, 2001
Eukaryotes silence gene expression in the presence of double-stranded RNA homologous to the silenced gene. Silencing occurs by the targeted degradation of mRNA. Biochemical reactions that recapitulate this phenomenon generate RNA fragments of 21--23 nucleotides from the double-stranded RNA.
openaire   +2 more sources

Infectious double-stranded poliovirus RNA

Virology, 1964
Abstract Evidence is presented for the existence of an infectious double-stranded poliovirus RNA in HeLa cells which is relatively resistant to RNase digestion, has a buoyant density of 1.58 g cm −3 in Cs 2 SO 4 , a sedimentation coefficient of 16–20 S in sucrose gradients, and elutes from methylated albumin columns at 0.84 M NaCl.
openaire   +2 more sources

Interferon stimulated by Double Stranded RNA

Nature, 1970
Interferon represents an interesting approach to the control of viral disease in man and his domestic animals, as this review shows, for it is a part of the animal's own recovery processes during naturally occurring infection and active against most viruses that cause acute infection.
openaire   +2 more sources

Duplex Structure of Double-Stranded RNA Provides Stability against Hydrolysis Relative to Single-Stranded RNA

Environmental Science & Technology, 2021
Ke Zhang, Tae Seok Moon, Kimberly M Parker   +2 more
exaly  

A nuclease specific for double-stranded RNA

Virology, 1967
H D, Robertson, R E, Webster, N D, Zinder   +2 more
openaire   +2 more sources

Transcriptional silencing and promoter methylation triggered by double-stranded RNA

EMBO Journal, 2000
A J M Matzke, M A Matzke, M F Mette
exaly