Results 21 to 30 of about 1,047,229 (199)

Amino Acid Permeases and Virulence in Cryptococcus neoformans. [PDF]

open access: yesPLoS ONE, 2016
Fungal opportunistic pathogens colonize various environments, from plants and wood to human and animal tissue. Regarding human pathogens, one great challenge during contrasting niche occupation is the adaptation to different conditions, such as ...
Kevin Felipe Cruz Martho   +11 more
doaj   +1 more source

Comparative analysis of casein complex and amino acid composition in single-humped and double-humped camel milk: Implications for dairy camel breeding [PDF]

open access: yesCaspian Journal of Environmental Sciences, 2023
The purpose of this work is to study the casein complex of camel milk and their amino acid composition. including the chemical composition and physico-chemical properties of milk of single-humped and double-humped camels, as well as the fractional ...
Kuanysh Syman   +6 more
doaj   +1 more source

Point mutations of the P53 gene, human hepatocellular carcinoma and aflatoxins [PDF]

open access: yes, 1993
The tumor suppressor p53 exerts important protective functions towards DNA-damaging agents. Its inactivation by allelic deletions or point mutations within the P53 gene as well as complex formation of wildtype p53 with cellular or viral proteins is a ...
Alexander L. Gerbes   +40 more
core   +1 more source

Amino acid residues that are important for Hyal2 function as a receptor for jaagsiekte sheep retrovirus

open access: yesRetrovirology, 2005
Background Infection by jaagsiekte sheep retrovirus (JSRV) and by enzootic nasal tumor virus (ENTV) depends on cell-surface expression of the virus entry receptor, hyaluronidase 2 (Hyal2).
Dirks Clarissa   +3 more
doaj   +1 more source

Formation and structure of the ferryl [Fe=O] in-termediate in the non-haem iron halogenase SyrB2: classical and QM/MM modelling agree [PDF]

open access: yes, 2017
To rationalise mechanistically the intriguing regio- and chemoselectivity patterns for different substrates of the non-haem iron/2-oxoglutarate dependent halogenase SyrB2, it is crucial to elucidate the structure of the pivotal [FeIV[double bond, length ...
Rugg, G., Senn, H.M.
core   +1 more source

Amino acid permeases in Cryptococcus neoformans are required for high temperature growth and virulence; and are regulated by Ras signaling.

open access: yesPLoS ONE, 2019
Cryptococcosis is an Invasive Fungal Infection (IFI) caused by Cryptococcus neoformans, mainly in immunocompromised patients. Therapeutic failure due to pathogen drug resistance, treatment inconstancy and few antifungal options is a problem. The study of
Crislaine Lambiase Calvete   +7 more
doaj   +1 more source

Effects of Low Temperature on the Amino Acid Composition of Wheat Grains

open access: yesAgronomy, 2022
Global warming can have detrimental effects on crop production formation, but the effect of low-temperature stress on crop quality should not be ignored.
Xinyi Hu   +9 more
doaj   +1 more source

Evolutionary Covariant Positions within Calmodulin EF-hand Sequences Promote Ligand Binding [PDF]

open access: yes, 2018
Intracellular calcium signaling is an essential regulatory mechanism through calcium-mediated signal transduction pathways involved in many cell processes, such as exocytosis, motility, apoptosis, excitability, transcription, and muscle contraction.
Vaidyanathan, Uma
core   +1 more source

The importance of cache domains in α2δ proteins and the basis for their gabapentinoid selectivity

open access: yesChannels, 2023
In this hybrid review, we have first collected and reviewed available information on the structure and function of the enigmatic cache domains in α2δ proteins.
Karen M Page   +4 more
doaj   +1 more source

Randomized double-blind trial of oral essential amino acids for dialysis-associated hypoalbuminemia [PDF]

open access: yesKidney International, 2000
Hypoalbuminemia is associated with substantial morbidity and mortality in dialysis patients.Subjects with a mean three-month prestudy serum albumin of 3.8 g/dL or less and who demonstrated >/=90% compliance during a two-week run-in period were randomized to 3.6 g of essential amino acids (EAAs) or placebo three times daily with meals for three months ...
Eustace, Joseph A.   +6 more
openaire   +2 more sources

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