Results 71 to 80 of about 516,365 (307)
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Edukacja demokratyczna a kreatywność
Filozofia Publiczna i Edukacja Demokratyczna, 2013 In democratic education should be used special forms and methods of teaching and learning. One of such method is drama, which stimulates creativity and self-expression.
Danuta A. Michałowska
doaj +1 more source
Should I Say Something? Dating and Sexual Aggression Bystander Intervention Among High School Youth [PDF]
, 2015 Using data from a sample of 218 high school youth from three high schools in New England (one rural, two urban), this brief discusses dating and sexual aggression bystander intervention among high school youth. Authors Katie Edwards, Robert Eckstein, and
Eckstein, Robert P +2 more
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Drama in coalfields and paddyfields [PDF]
, 2008 Following the tsunami in 2004 Derbyshire Secondary School Tibshelf now works closely with schools in Sri Lanka, Ava Hunt works with young people and English Teachers and the power of the use of Drama in Education as an educative tool.Drawing on a range ...
Hunt, Ava
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Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Jiaoshi jiaoyu xuebaoDrama is an art presenting contradictions and conflicts through verbal dialogues and body movements. Remodeling moral education classrooms with drama means placing students in a class of "situations, conflicts, experiences and reflections", allowing ...
LIU Zhenzhen, ZHENG Jiafu
doaj +1 more source
Hyvinvointia ja menestystä elämään draamasta [PDF]
, 2011 Opinnäytetyössäni käsittelen draamakasvatuksen mahdollista käyttöä kouluopetuksessa tehokkaana pedagogisena metodina ja sen tarjoamia opiskelijan elämän laatua parantavia vaikutuksia.
Kivistö-Leikkonen, Katja
core
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Teacher Education through Drama. CLIL Practice in the Spanish Context
Estudios sobre Educación, 2017 The paper is inspired by the increasing educational development of bilingualism and CLIL in Spain and the need to explore new teaching methodologies in initial teacher education in this field.
Agata Muszyńska +2 more
doaj +1 more source