Results 161 to 170 of about 15,397 (180)

Drosha and DGCR8 in MicroRNA Biogenesis

2012
Abstract Drosha and DGCR8 (also called Pasha), together known as the Microprocessor complex, are responsible for cleaving canonical microRNA primary transcripts (pri-miRNAs) to produce microRNA precursors (pre-miRNAs) in animals. This specific cleavage serves as the entrance to the microRNA (miRNA) maturation pathway.
openaire   +1 more source

Preparation and Analysis of Drosha

2005
Yoontae, Lee, V Narry, Kim
openaire   +2 more sources

Cryo-EM Structures of Human Drosha and DGCR8 in Complex with Primary MicroRNA

Molecular Cell, 2020
Byung-Cheon Jeong, Emily Herrell, Shanshan Li   +2 more
exaly  

Drosha-independent miR-6778–5p strengthens gastric cancer stem cell stemness via regulation of cytosolic one-carbon folate metabolism

Cancer Letters, 2020
Manran Liu, Yina Qiao, Yixuan Hou
exaly  

Dicer and Drosha in Ovarian Cancer

New England Journal of Medicine, 2009
openaire   +1 more source

Re-evaluation of the roles of DROSHA , Exportin 5 , and DICER in microRNA biogenesis

Proceedings of the National Academy of Sciences of the United States of America, 2016
Young-Kook Kim, Boseon Kim, Kim V Narry   +2 more
exaly  

Drosha

2008
openaire   +1 more source

Down-regulation of the miRNA master regulators Drosha and Dicer is associated with specific subgroups of breast cancer

European Journal of Cancer, 2011
Konstantin Dedes, Rachael Natrajan, Jorge Reis-Filho   +2 more
exaly  

Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha

EMBO Journal, 2005
Rui Yi, Bryan Cullen
exaly  

Lower and upper stem–single-stranded RNA junctions together determine the Drosha cleavage site

Proceedings of the National Academy of Sciences of the United States of America, 2013
Hongming Ma, Haoquan Wu, Yonggan Wu
exaly