Results 141 to 150 of about 15,397 (180)

Knowing is not enough; we must apply: the case for rigorous microRNA annotation standards. [PDF]

Nucleic Acids Res
Hackenberg M, Kalogeropoulos P, Peterson KJ, Friedländer MR, Fromm B.   +4 more
europepmc   +1 more source

Mapping of in vivo cleavage sites uncovers a major role for yeast RNase III in regulating protein-coding genes. [PDF]

Elife
Notice-Sarpaning LA, Catala M, Stuart C, Elela SA, van Hoof A.   +4 more
europepmc   +1 more source

The Life of MicroRNAs: Biogenesis, Function and Decay in Cancer. [PDF]

Biomolecules
Ding S, Wang P.
europepmc   +1 more source

Infectious bronchitis-virus-like QX strain transmission, pathogenesis, replication, and host miRNA biogenesis pathway hijacking mechanism. [PDF]

Front Cell Infect Microbiol
Khan A, Khan IA, Huang C, Luo Q, Qadeer A, Jia L, Aboul-Soud MAM, Alkubaisi NA, Chen Z.   +8 more
europepmc   +1 more source

An imbalance between proliferation and differentiation underlies the development of microRNA-defective pineoblastoma. [PDF]

Genes Dev
Fraire CR, Desai K, Jagadeeswaran I, Obalapuram UA, Mendyka LK, Rajaram V, Sebastian T, Wang Y, Onel K, Lee J, Skapek SX, Chen KS.   +11 more
europepmc   +1 more source

Germline Pathogenic DROSHA Variants Are Linked to Pineoblastoma and Wilms Tumor Predisposition. [PDF]

Clin Cancer Res
Fiorica PN, Golmard L, Kim J, Bao R, Lin FY, Roy A, Pribnow A, Perrino MR, Masliah-Planchon J, Michalak-Provost S, Wong J, Filser M, Stoppa-Lyonnet D, Bourdeaut F, Brahimi A, Ingster O, Saulnier Sholler G, Jackson SA, Sasaki MM, Fowler T, Ng A, Corbett RJ, Kaufman RS, Haley JS, Carey DJ, Huang KL, Diskin SJ, Rokita JL, Al-Kateb H, McGee RB, Schiffman JD, Chen KS, Stewart DR, Williams Parsons D, Plon SE, Schultz KAP, Onel K.   +36 more
europepmc   +1 more source

Structural Basis for pri-miRNA Recognition by Drosha [PDF]

Molecular Cell, 2020
A commencing and critical step in miRNA biogenesis involves processing of pri-miRNAs in the nucleus by Microprocessor. An important, but not completely understood, question is how Drosha, the catalytic subunit of Microprocessor, binds pri-miRNAs and correctly specifies cleavage sites.
Hongwei Wang, Chao-Pei Liu, Jia Wang
exaly   +3 more sources

Dysregulated Expression of Dicer and Drosha in Breast Cancer

Pathology and Oncology Research, 2011
Large-scale profiling approaches have revealed global down-regulation of microRNAs (miRNAs) in several human cancer types including breast cancer. Altered expression of Dicer and Drosha, two key enzymes in the miRNA maturation, is believed to be one of the most important mechanisms.
Yi Wan, Qing-Xia Fan
exaly   +3 more sources

Some of the next articles are maybe not open access.

Related searches:

Characterization of shrimp Drosha in virus infection

Fish and Shellfish Immunology, 2012
RNA interference (RNAi) mediated by microRNA (miRNA) is an evolutionarily conserved mechanism of posttranscriptional gene regulation in all eukaryotes, involving in natural antiviral immunity. The RNAase III Drosha is a key component for miRNA maturation. To date, however, the roles of Drosha in virus infection remain to be addressed.
Xiaobo Zhang
exaly   +3 more sources