Results 141 to 150 of about 16,723 (215)

Upregulation of microRNA processing enzymes Drosha and Dicer in gestational diabetes mellitus [PDF]

Background& Objective: MicroRNAs (miRNAs) have been shown to play important roles in diverse cellular processes and linked to variety of disorders. Dicer and Drosha are two major enzymes in the miRNA biogenesis process.
رحیمی, گیتی, خدابخش, مهنوش, پیری دوگاهه, هادی   +2 more
core  

PymiRa: A rapid and accurate classification tool for small non-coding RNAs, including microRNAs. [PDF]

PLoS Comput Biol
Scurlock ZGL, Scarpini CG, Coleman N, Murray MJ, Enright AJ.   +4 more
europepmc   +1 more source

Disrupted miRNA Biogenesis Machinery Reveals Common Molecular Pathways and Diagnostic Potential in MDS and AML. [PDF]

Biomedicines
Çevik K, Ay ME, Tombak A, Ay Öİ, Karakaş Ü, Erdal ME.   +5 more
europepmc   +1 more source

Landscape of microRNA and target expression variation and covariation in single mouse embryonic stem cells. [PDF]

Genome Res
Tarbier M, Mackowiak SD, Sekar V, Bonath F, Yapar E, Fromm B, Faridani OR, Biryukova I, Friedländer MR.   +8 more
europepmc   +1 more source

SARS-CoV-2 Infection of Lung Epithelia Leads to an Increase in the Cleavage and Translocation of RNase-III Drosha; Loss of Drosha Is Associated with a Decrease in Viral Replication. [PDF]

Genes (Basel)
Winters MT, Westemeier-Rice ES, Rawson TW, Patel KJ, Sankey GM, Dixon-Gross M, McHugh OR, Hashemipour N, Carroll ML, Wilkerson IR, Martinez I.   +10 more
europepmc   +1 more source

Non-Canonical Compartmentalization of DROSHA Protein at the Golgi Apparatus: miRNA Biogenesis-Independent Functionality in Human Cancer Cells of Diverse Tissue Origin. [PDF]

Int J Mol Sci
Theotoki EI, Kakoulidis P, Papavassiliou KA, Nikolakopoulos KS, Vlachou EN, Basdra EK, Papavassiliou AG, Tsitsilonis OE, Voutsinas GE, Velentzas AD, Anastasiadou E, Stravopodis DJ.   +11 more
europepmc   +1 more source

A non-canonical role for HIF-1α: redirecting DGCR8 to the RNA exosome for snoRNA degradation and translational modulation. [PDF]

Nucleic Acids Res
Li JN, Wang MY, Lo C, Yen L, Yu CH, Lyu YJ, Chen PS.   +6 more
europepmc   +1 more source

A microRNA generated via lysosomal processing of ribosomal RNA suppresses proinflammatory responses. [PDF]

Life Sci Alliance
Michael D, Feldmesser E, Rajan KS, Lubelsky Y, Bashan A, Damalas A, Ben Zvi S, Friedberg A, Eitan N, Erez S, Yonath A, Ulitsky I, Oren M.   +12 more
europepmc   +1 more source

Recurrent genetic alterations in epigenetically defined pineoblastoma subtypes. [PDF]

Acta Neuropathol Commun
Goschzik T, Yuan M, Pfaff E, Müller MEB, Mynarek M, Dörner E, Jones DTW, Pfister SM, Rutkowski S, Pietsch T.   +9 more
europepmc   +1 more source

An intrinsically disordered region of Drosha selectively promotes miRNA biogenesis independent of tissue-specific Microprocessor condensates. [PDF]

Genes Dev
Yang B, Galletta BJ, Sakhawala RM, Rusan NM, McJunkin K.   +4 more
europepmc   +1 more source