Results 1 to 10 of about 372,099 (211)

Drosophila RecQ4 Is Directly Involved in Both DNA Replication and the Response to UV Damage in S2 Cells. [PDF]

, 2012
The RecQ4 protein shows homology to both the S.cerevisiae DNA replication protein Sld2 and the DNA repair related RecQ helicases. Experimental data also suggest replication and repair functions for RecQ4, but the precise details of its involvement remain
Cotterill, S, Crevel, G, Crevel, I, Hamid, S, Hoa, L, Miyata, S, Vo, N   +6 more
core   +13 more sources

Site-Specific Profiling of N-Glycans in Drosophila melanogaster

Frontiers in Bioscience-Landmark, 2023
Background: Drosophila melanogaster is a well-studied and highly tractable genetic model system for deciphering the molecular mechanisms underlying various biological processes.
Fei Zhao, Chenyu Jia, Fangyu He, Meiting Hu, Xingyu Guo, Jiaxin Zhang, Xuesong Feng   +6 more
doaj   +1 more source

The S-palmitoylome and DHHC-PAT interactome of Drosophila melanogaster S2R+ cells indicate a high degree of conservation to mammalian palmitoylomes.

PLoS ONE, 2022
Protein S-palmitoylation, the addition of a long-chain fatty acid to target proteins, is among the most frequent reversible protein modifications in Metazoa, affecting subcellular protein localization, trafficking and protein-protein interactions.
Elena Porcellato, Juan Carlos González-Sánchez, Constantin Ahlmann-Eltze, Mahmoud Ali Elsakka, Itamar Shapira, Jürgen Fritsch, Juan Antonio Navarro, Simon Anders, Robert B Russell, Felix T Wieland, Christoph Metzendorf   +10 more
doaj   +1 more source

Drosophila Rbp6 is an orthologue of vertebrate Msi-1 and Msi-2, but does not function redundantly with dMsi to regulate germline stem cell behaviour. [PDF]

PLoS ONE, 2012
The vertebrate RNA-binding proteins, Musashi-1 (Msi-1) and Musashi-2 (Msi-2) are expressed in multiple stem cell populations. A role for Musashi proteins in preventing stem cell differentiation has been suggested from genetic analysis of the Drosophila ...
Nicole A Siddall, Marina Kalcina, Timothy M Johanson, Adrian C Monk, Franca Casagranda, Reeva P Been, Eileen A McLaughlin, Gary R Hime   +7 more
doaj   +1 more source

Construction of an alpaca immune antibody library for the selection of nanobodies against Drosophila melanogaster proteins

Frontiers in Bioengineering and Biotechnology, 2023
Introduction:Drosophila melanogaster is a model organism for studying developmental biology and human neural disorders. Nanobodies are the variable domains of the heavy chains of camelid heavy-chain antibodies (VHHs) with high affinity to their antigens ...
Jianxiang Qiu, Jie Li, Zhen Zhang, Shirui Dong, Xiaomei Ling, Zhixin Fang, Quanshou Ling, Zhixin Huang   +7 more
doaj   +1 more source

HP1B is a euchromatic Drosophila HP1 homolog with links to metabolism. [PDF]

PLoS ONE, 2018
Heterochromatin Protein 1 (HP1) proteins are an important family of chromosomal proteins conserved among all major eukaryotic lineages. While HP1 proteins are best known for their role in heterochromatin, many HP1 proteins function in euchromatin as well.
Benjamin B Mills, Andrew D Thomas, Nicole C Riddle   +2 more
doaj   +1 more source

Effect of the gene doublesex of anastrepha on the somatic sexual development of Drosophila.

PLoS ONE, 2009
BackgroundThe gene doublesex (dsx) is at the bottom of the sex determination genetic cascade and is transcribed in both sexes, but gives rise to two different proteins, DsxF and DsxM, which impose female and male sexual development respectively via the ...
Mercedes Alvarez, María Fernanda Ruiz, Lucas Sánchez   +2 more
doaj   +1 more source

Construction and analysis of the protein-protein interaction network of visual system in Drosophila [PDF]

Network Biology, 2023
Insects are one of the most widely distributed animals on earth, and their visual systems have strong adaptability, deeply affecting their survival, reproduction, diet, and environmental adaptation.
JiaNing Sun, WenJun Zhang
doaj  

Distribution of DNA replication proteins in Drosophila cells

BMC Cell Biology, 2007
Background DNA replication in higher eukaryotic cells is organized in discrete subnuclear sites called replication foci (RF). During the S phase, most replication proteins assemble at the RF by interacting with PCNA via a PCNA binding domain (PBD).
Leonhardt Heinrich, Easwaran Hariharan P, Cardoso M Cristina   +2 more
doaj   +1 more source

A widespread family of heat-resistant obscure (Hero) proteins protect against protein instability and aggregation.

PLoS Biology, 2020
Proteins are typically denatured and aggregated by heating at near-boiling temperature. Exceptions to this principle include highly disordered and heat-resistant proteins found in extremophiles, which help these organisms tolerate extreme conditions such
Kotaro Tsuboyama, Tatsuya Osaki, Eriko Matsuura-Suzuki, Hiroko Kozuka-Hata, Yuki Okada, Masaaki Oyama, Yoshiho Ikeuchi, Shintaro Iwasaki, Yukihide Tomari   +8 more
doaj   +1 more source