Results 41 to 50 of about 6,612,897 (317)

MOESM2 of Potential drugâ drug interactions among elderly patients admitted to medical ward of Ayder Referral Hospital, Northern Ethiopia: a cross sectional study

, 2016
Additional file 2. STROBE Statementâ checklist of items that should be included in reports of observational studies.
Fantaye Teka, Gebrehiwot Teklay, Eskindeir Ayalew, Terefe Teshome   +3 more
openaire   +1 more source

A Review of CYP-Mediated Drug Interactions: Mechanisms and In Vitro Drug-Drug Interaction Assessment

Biomolecules
Drug metabolism is a major determinant of drug concentrations in the body. Drug-drug interactions (DDIs) caused by the co-administration of multiple drugs can lead to alteration in the exposure of the victim drug, raising safety or effectiveness concerns.
Jonghwa Lee, Jessica L. Beers, Raeanne M. Geffert, Klarissa D Jackson   +3 more
semanticscholar   +1 more source

Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use

Journal of Clinical Medicine, 2019
Cannabidiol (CBD) is ubiquitous in state-based medical cannabis programs and consumer products for complementary health or recreational use. CBD has intrinsic pharmacologic effects and associated adverse drug events (ADEs) along with the potential for ...
Joshua D. Brown, A. Winterstein
semanticscholar   +1 more source

Additional file 1: of Research on the mechanism of drugâ drug interaction between salvianolate injection and aspirin based on the metabolic enzyme and PK-PD model: study protocol for a PK-PD trial

, 2018
SPIRIT 2013 checklist. (DOC 108 kb)
Zhang, Wantong, Zhu, Baochen, Cao, Weiyi, Li, Rui, Wang, Shuge, Gao, Rui   +5 more
openaire   +1 more source

Medication Appropriateness, Polypharmacy, and Drug-Drug Interactions in Ambulatory Elderly Patients with Cardiovascular Diseases at Tikur Anbessa Specialized Hospital, Ethiopia

Clinical Interventions in Aging, 2022
Limi Adem, Gobezie T Tegegne Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Science, Addis Ababa University, Addis Ababa, EthiopiaCorrespondence: Gobezie T Tegegne, Email gobezie.temesgen@aau.edu.etBackground ...
Adem L, Tegegne GT
doaj  

Bee Pollen as a Source of Biopharmaceuticals for Neurodegeneration and Cancer Research: A Scoping Review and Translational Prospects

Molecules
Bee Pollen (BP) has many advantageous properties relying on its multitargeting potential, a new tendency in managing many challenging illnesses. In cancer and neurodegeneration, the multiple effects of BP could be of unequaled importance and need further
Rachid Kacemi, Maria G. Campos
doaj   +1 more source

Magnitude of Drug–Drug Interactions in Special Populations

Pharmaceutics, 2022
Drug–drug interactions (DDIs) are one of the most frequent causes of adverse drug reactions or loss of treatment efficacy. The risk of DDIs increases with polypharmacy and is therefore of particular concern in individuals likely to present comorbidities (
Sara Bettonte, Mattia Berton, Catia Marzolini   +2 more
doaj   +1 more source

Bee Pollen Phytochemicals and Nutrients as Unequaled Pool of Epigenetic Regulators: Implications for Age-Related Diseases

Foods
Bee pollen is characterized by an exceptional diversity and abundance of micronutrients and bioactive phytochemicals. This richness remains very sparsely investigated, but accumulating evidence strongly supports a promising future for bee pollen in human
Rachid Kacemi, Maria G. Campos
doaj   +1 more source

A Phase 1, Open‐Label, Pharmacokinetic Trial to Investigate Possible Drug‐Drug Interactions Between Clobazam, Stiripentol, or Valproate and Cannabidiol in Healthy Subjects

Clinical pharmacology in drug development, 2019
GW Pharmaceuticals’ formulation of highly purified cannabidiol oral solution is approved in the United States for seizures associated with Lennox‐Gastaut and Dravet syndromes in patients aged ≥2 years, for which clobazam, stiripentol, and valproate are ...
Gilmour Morrison, Julie Crockett, G. Blakey, K. Sommerville   +3 more
semanticscholar   +1 more source

Pharmacologic Treatment of Transplant Recipients Infected With SARS-CoV-2: Considerations Regarding Therapeutic Drug Monitoring and Drug–Drug Interactions

Therapeutic Drug Monitoring, 2020
Background: COVID-19 is a novel infectious disease caused by the severe acute respiratory distress (SARS)-coronavirus-2 (SARS-CoV-2). Several therapeutic options are currently emerging but none with universal consensus or proven efficacy.
L. Elens, L. Langman, D. Hesselink, S. Bergan, D. Moes, M. Molinaro, R. Venkataramanan, F. Lemaitre   +7 more
semanticscholar   +1 more source